{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T16:18:30Z","timestamp":1793377110614,"version":"4.5.0"},"reference-count":20,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,7,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Introduction<\/jats:title>\n                  <jats:p>A total of three cases of childhood central nervous system (CNS) echinococcosis with spinal or posterior fossa involvement having rare localizations, have been presented.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Case presentation<\/jats:title>\n                  <jats:p>A 7-year-old boy with spinal involvement applied to our hospital with left leg weakness and inability to walk. A 16-year-old girl with posterior fossa involvement had peripheral facial paralysis, while a 9-year-old girl had headache and vomiting. These cases, diagnosed with cystic echinococcosis with the necessary laboratory and imaging methods, improved with appropriate medical treatment and surgery.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Discussion<\/jats:title>\n                  <jats:p>Especially in endemic areas, it should be kept in mind that cystic echinococcosis may present with CNS involvement and should become to mind in the differential diagnosis when neurological findings are detected.<\/jats:p>\n                  <jats:p>Lay Summary: With this report, we attempted to share our experience with cystic echinococcosis in the spinal region and posterior fossa in three children over 1 year, including a description of associated signs and symptoms as well as laboratory and radiological findings. It should be kept in mind that cystic echinococcosis may present with CNS involvement in endemic areas and should be considered in the differential diagnosis when neurological findings are detected. Afterward, the diagnosis should be confirmed with appropriate laboratory and imaging methods. In these cases, rapid recovery can be achieved with appropriate surgical intervention as well as medical treatment.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/tropej\/fmab056","type":"journal-article","created":{"date-parts":[[2021,6,17]],"date-time":"2021-06-17T19:10:59Z","timestamp":1623957059000},"source":"Crossref","is-referenced-by-count":9,"title":["A rare case series of central nervous system cystic echinococcosis"],"prefix":"10.1093","volume":"67","author":[{"given":"Aysegul","family":"Elvan-Tuz","sequence":"first","affiliation":[{"name":"Department of Pediatric Infectious Diseases, University of Health Sciences, Tepecik Training and Research Hospital, Izmir, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eda","family":"Karadag-Oncel","sequence":"additional","affiliation":[{"name":"Department of Pediatric Infectious Diseases, University of Health Sciences, Tepecik Training and Research Hospital, Izmir, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahu","family":"Kara-Aksay","sequence":"additional","affiliation":[{"name":"Department of Pediatric Infectious Diseases, University of Health Sciences, Tepecik Training and Research Hospital, Izmir, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatma Ceren","family":"Sarioglu","sequence":"additional","affiliation":[{"name":"Department of Radiology, University of Health Sciences, Tepecik Training and Research Hospital, Izmir, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Karadag","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Health Sciences, Tepecik Training and Research Hospital, Izmir, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dilek","family":"Yilmaz-Ciftdogan","sequence":"additional","affiliation":[{"name":"Department of Pediatric Infectious Diseases, Izmir Katip Celebi University, Izmir, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,7,2]]},"reference":[{"key":"2021070811480474300_fmab056-B1","doi-asserted-by":"crossref","first-page":"322","DOI":"10.4103\/1793-5482.162719","article-title":"Giant hydatid cyst in the posterior fossa of a child","volume":"10","author":"Fakhouri","year":"2015","journal-title":"Asian J Neurosurg"},{"key":"2021070811480474300_fmab056-B2","doi-asserted-by":"crossref","DOI":"10.1007\/s00383-021-04904-3","article-title":"An unsolved problem in developing countries: hydatid cysts in children","author":"\u00d6ztorun","year":"2021","journal-title":"Pediatr Surg Int"},{"key":"2021070811480474300_fmab056-B3","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1016\/S0140-6736(03)14573-4","article-title":"Echinococcosis","volume":"362","author":"McManus","year":"2003","journal-title":"Lancet"},{"key":"2021070811480474300_fmab056-B4","doi-asserted-by":"crossref","first-page":"727","DOI":"10.4103\/0971-3026.32333","article-title":"CT and MRI features of the typical and atypical intracranial hydatid cysts: report of five cases","volume":"16","author":"Ravalji","year":"2006","journal-title":"Indian J Radiol Imaging"},{"key":"2021070811480474300_fmab056-B5","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1148\/rg.232025704","article-title":"Hydatid disease from head to toe","volume":"23","author":"Polat","year":"2003","journal-title":"Radiographics"},{"key":"2021070811480474300_fmab056-B6","doi-asserted-by":"crossref","first-page":"100","DOI":"10.4103\/0028-3886.25138","article-title":"13-year-old boy with cerebellar cystic mass","volume":"54","author":"Yasha","year":"2006","journal-title":"Neurol India"},{"key":"2021070811480474300_fmab056-B7","doi-asserted-by":"crossref","first-page":"1967","DOI":"10.1007\/s00381-018-3883-x","article-title":"Hydatid disease (Echinococcus) of the central nervous system","volume":"34","author":"Padayachy","year":"2018","journal-title":"Childs Nerv Syst"},{"key":"2021070811480474300_fmab056-B8","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1097\/00000441-200504000-00006","article-title":"Primary intradural extramedullary hydatid cyst","volume":"329","author":"Kahilogullari","year":"2005","journal-title":"Am J Med Sci"},{"key":"2021070811480474300_fmab056-B9","first-page":"347","article-title":"Computed tomography findings in cerebral hydatid disease","volume":"21","author":"Wani","year":"2011","journal-title":"Turk Neurosurg"},{"key":"2021070811480474300_fmab056-B10","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1007\/s00586-009-1006-9","article-title":"Intradural extramedullary primary hydatid cyst of the spine in a child: a very rare presentation. 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