{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T03:51:50Z","timestamp":1761709910968,"version":"3.41.2"},"reference-count":35,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Kunming Municipal Health and Health Commission"},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82060291"],"award-info":[{"award-number":["82060291"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,10,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>Vitamin D is an essential nutrient that regulates the activity of calcium and bone hormones throughout life; however, vitamin D levels in children, which is the most crucial period during human development, has not been established.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>As the first descriptive study of serum vitamin D levels in children in Yunnan Province, we determined the serum vitamin D levels in children 0\u20124\u2009years of age who underwent physical examinations at Kunming Children's Hospital, and the association between the serum vitamin D level and the calcium, phosphorus and alkaline levels.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Vitamin D levels in children were highest in the summer months and lowest in the winter months. Vitamin D deficiency was more common in girls than boys. A social-economic effect was shown, as evidenced by the significantly higher serum vitamin D levels in children from the top five cities compared with the lower-ranked cities. Moreover, we also demonstrated a significant correlation between vitamin D and serum calcium levels.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Our study suggested that sex and age affected the vitamin D levels of children, and a reasonable reference range in children 0\u20134\u2009years of age in Yunnan Province was determined.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/tropej\/fmab093","type":"journal-article","created":{"date-parts":[[2021,10,25]],"date-time":"2021-10-25T11:08:37Z","timestamp":1635160117000},"source":"Crossref","is-referenced-by-count":4,"title":["The Pattern of Vitamin D Levels in Children 0\u20134 Years of Age in Yunnan Province"],"prefix":"10.1093","volume":"67","author":[{"given":"Yuqin","family":"Wu","sequence":"first","affiliation":[{"name":"Special Ward, Kunming Children's Hospital, Kunming 650228, Yunnan Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanfei","family":"Yang","sequence":"additional","affiliation":[{"name":"Special Ward, Kunming Children's Hospital, Kunming 650228, Yunnan Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao","family":"Xiao","sequence":"additional","affiliation":[{"name":"Special Ward, Kunming Children's Hospital, Kunming 650228, Yunnan Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lin","family":"Wang","sequence":"additional","affiliation":[{"name":"Special Ward, Kunming Children's Hospital, Kunming 650228, Yunnan Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zheng","family":"Yin","sequence":"additional","affiliation":[{"name":"Special Ward, Kunming Children's Hospital, Kunming 650228, Yunnan Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3920-1654","authenticated-orcid":false,"given":"Yangfang","family":"Li","sequence":"additional","affiliation":[{"name":"Special Ward, Kunming Children's Hospital, Kunming 650228, Yunnan Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,11,17]]},"reference":[{"key":"2021111805331569500_fmab093-B1","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1007\/s00198-003-1491-3","article-title":"Vitamin D status and its relationship with bone mineral density in healthy Asian Indians","volume":"15","author":"Arya","year":"2004","journal-title":"Osteoporos Int"},{"key":"2021111805331569500_fmab093-B2","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1016\/S0140-6736(00)04831-5","article-title":"25-Hydroxyvitamin D-1alpha-hydroxylase in normal and malignant colon 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and long-term safety of weekly high-dose vitamin D3 supplementation in school children","volume":"93","author":"Maalouf","year":"2008","journal-title":"J Clin Endocrinol Metab"},{"key":"2021111805331569500_fmab093-B33","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1007\/s11442-019-1651-9","article-title":"The effects of urbanization on ecosystem services for biodiversity conservation in southernmost Yunnan Province, Southwest China","volume":"29","author":"Cheng","year":"2019","journal-title":"J Geogr Sci"},{"key":"2021111805331569500_fmab093-B34","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1542\/peds.2008-1862","article-title":"Prevention of rickets and vitamin D deficiency in infants, children, and adolescents","volume":"122","author":"Wagner","year":"2008","journal-title":"Pediatrics"},{"first-page":"190","year":"2008","author":"Editorial Board of Chinese Journal of Pediatrics; Subspecialty Group of Child Health 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