{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T22:45:54Z","timestamp":1771541154269,"version":"3.50.1"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Vice-Chancellor for Research, Isfahan University of Medical Sciences, Isfahan, Iran","award":["IR.MUI.RESEARCH.REC.1399.332"],"award-info":[{"award-number":["IR.MUI.RESEARCH.REC.1399.332"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,10,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Introduction<\/jats:title>\n                  <jats:p>There is limited data on newborns born to mothers with COVID-19 infection. This multicenter cohort study aimed to investigate the clinical characteristics and outcomes of neonates born to mothers with and without COVID-19 infection to fill a gap in the literature review.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>The medical records of all neonates in Isfahan, Iran, between October 2020 and March 2021, were retrospectively reviewed.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Among the 600 neonates in this study, 255 (42.5%) were in the infected group and 345 (57.5%) were assigned to the control group as they were born to non-infected mothers. In the infected group, sepsis, fever and pneumothorax were detected in 3 (1.2%), 3 (1.2%) and 4 (1.6%) neonates, respectively, compared with no case in the control group. In the infected group, neonatal respiratory distress (NRDS) (32, 12.5%) was significantly higher than the control group (27, 10.6%). Asphyxia in the infected group was 22(6.4%), compared with 19 (5.5%), in the control group. Preterm labor (PTL) (55, 21.65%), premature rupture of membranes (PROMs) (24, 9.4%) and intra-uterine growth retardation (IUGR) (15, 5.9%) were significantly higher in women with COVID-19 (45, 13.0%, 4, 1.2% and 7, 2.0%, respectively). Low birth weight (LBW) accounted for 42 (16.5%) neonates in the infected group and 25 (7.2%) in the control group (p &amp;lt; 0.05). Of the 255 neonates born to infected mothers, 38 (14.9%) were admitted to the Neonatal Intensive Care Unit (NICU), compared with 31 out of 345 (9.0%) in the control group (p &amp;lt; 0.05). RT-PCR test results were positive in two newborns (0.8%), one of whom died of necrotizing enterocolitis.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>As a result of maternal COVID-19 infections, neonates experienced higher rates of sepsis, fever, pneumothorax, asphyxia and NRDS in addition to PTL, PROMs, IUGR, and LBW.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/tropej\/fmab094","type":"journal-article","created":{"date-parts":[[2021,11,5]],"date-time":"2021-11-05T20:15:52Z","timestamp":1636143352000},"source":"Crossref","is-referenced-by-count":12,"title":["Impact of COVID-19 Infection on Neonatal Birth Outcomes"],"prefix":"10.1093","volume":"67","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7780-8580","authenticated-orcid":false,"given":"Maryam","family":"Vizheh","sequence":"first","affiliation":[{"name":"Department of Reproductive Health and Midwifery, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran 1419733171, Iran"},{"name":"Department of Management, Macquarie Business School, Macquarie University, NSW 2109, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5128-9578","authenticated-orcid":false,"given":"Maryam","family":"Allahdadian","sequence":"additional","affiliation":[{"name":"Department of Midwifery, Nursing and Midwifery Faculty, Falavarjan Branch, Islamic Azad University, Isfahan 155\/84515, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salut","family":"Muhidin","sequence":"additional","affiliation":[{"name":"Department of Management, Macquarie Business School, Macquarie University, NSW 2109, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3955-4628","authenticated-orcid":false,"given":"Mahboubeh","family":"Valiani","sequence":"additional","affiliation":[{"name":"Nursing and Midwifery Care Research Center, Midwifery and Reproductive Health Department, School of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan 81746-73461, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khadijeh","family":"Bagheri","sequence":"additional","affiliation":[{"name":"Alzahra Hospital, Research Committee, Midwifery and Reproductive Health Department, School of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan 81746-73461, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Forogh","family":"Borandegi","sequence":"additional","affiliation":[{"name":"Amin Hospital, Research Committee, Isfahan University of Medical Sciences, Isfahan 81746-73461, 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