{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:19:16Z","timestamp":1753877956831,"version":"3.41.2"},"reference-count":24,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2022,2,3]],"date-time":"2022-02-03T00:00:00Z","timestamp":1643846400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,2,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>We aimed to evaluate blood pressure (BP) in Indian children who had similar demographic characteristics but hailed from different altitudes.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>BP of school going children, aged 5 to 12\u2009years, at five different locations varying in altitude (near sea level: n\u2009=\u2009425; 2000 feet: n\u2009=\u2009244; 4000 feet: n\u2009=\u2009248; 6000 feet: n\u2009=\u2009242 and 8000 feet: n\u2009=\u2009250) was measured in a mountainous district in Himalaya. Systolic blood pressure (SBP) and diastolic blood pressure (DBP) were recorded by aneroid sphygmomanometer in the sitting posture using a calibrated instrument and four trained resident doctors. The average of three readings was taken.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Of the 1229 children whose data were analyzed, 50.4% were boys. SBP showed a progressive rise from 99.5 (4.00) mmHg [mean (standard deviation)] at near sea level to 106.7 (4.17) mmHg at 8000 feet. Similarly, DBP showed a rise from 60.1 (3.67) mmHg to 66.8 (4.58) mmHg over the same altitude range. Analysis of covariance for BP variation with altitude, with age as covariate, indicated a modest but statistically significant rise in both SBP and DBP with altitude. Higher BP values was noted among children residing at higher than at lower altitude (0.8% at sea level to 18.8% at 8000 feet). Correlations between SBP and DBP values and height and weight, though positive and significant at p\u2009&amp;lt;\u20090.01 level, were weak.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>These data will help in correct interpretation of BP readings in children residing at high altitude.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/tropej\/fmac010","type":"journal-article","created":{"date-parts":[[2022,1,25]],"date-time":"2022-01-25T12:15:17Z","timestamp":1643112917000},"source":"Crossref","is-referenced-by-count":1,"title":["Blood Pressure Variation with Altitudes in Children: A Cross-Sectional Observational Study from Himalayan Hills"],"prefix":"10.1093","volume":"68","author":[{"given":"Bhukya","family":"Rajashekar","sequence":"first","affiliation":[{"name":"Department of Pediatrics, North Bengal Medical College, Darjeeling, West Bengal, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Uttam Kumar","family":"Sarkar","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, North Bengal Medical College, Darjeeling, West Bengal, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Debadyuti","family":"Datta","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, North Bengal Medical College, Darjeeling, West Bengal, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tanushree","family":"Mondal","sequence":"additional","affiliation":[{"name":"Community Medicine, Medical College Kolkata, Kolkata, West Bengal, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mihir","family":"Sarkar","sequence":"additional","affiliation":[{"name":"Pediatric Medicine, Medical College Kolkata, Kolkata, West Bengal, 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