{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T08:14:36Z","timestamp":1758269676341,"version":"3.41.2"},"reference-count":24,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2022,2,3]],"date-time":"2022-02-03T00:00:00Z","timestamp":1643846400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,2,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>This study compared the risk of hypoglycemia within 72\u2009h of life in infants with and without exposure to antenatal dexamethasone in the late preterm period (34\u2013366\/7 week\u2019s gestational age).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>This prospective cohort study was conducted in a tertiary care neonatal unit of Eastern India from May 2021 to November 2021. Babies in the exposed group received at least one dose of antenatal dexamethasone in the late preterm period between 7\u2009days before delivery and birth. \u2018Complete course\u2019 of antenatal steroid was defined as four doses of injection dexamethasone at 12\u2009h intervals and &amp;lt;4 doses were considered as \u2018Partial course\u2019. Primary outcome was incidence of hypoglycemia within 72\u2009h of life, defined as whole blood glucose &amp;lt;45\u2009mg\/dl.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Total 298 infants (98 in control, 134 in partial and 66 in complete group) were assessed for final outcome. No significant difference in outcomes were seen in the exposed group compared to unexposed group. However, incidence of hypoglycemia within 72\u2009h (complete vs. partial p= 0.008, complete vs. control p=0.005) and 12\u2009h of life (complete vs. partial p=0.013, complete vs. control p=0.013) was significantly less in complete steroid group. Logistic regression analysis revealed complete course of antenatal corticosteroid significantly decreased the risk of hypoglycemia [adjusted odds ratio, 95% confidence interval (CI) 0.15 (0.03\u20130.69), p=0.015]. Number needed to be exposed for one additional benefit was 7 (95% CI, 6.35\u201322.14).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Complete course of dexamethasone administered to mothers at risk of late preterm delivery reduces risk of neonatal hypoglycemia within 72\u2009h of life.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/tropej\/fmac021","type":"journal-article","created":{"date-parts":[[2022,2,15]],"date-time":"2022-02-15T20:19:38Z","timestamp":1644956378000},"source":"Crossref","is-referenced-by-count":5,"title":["Effect of Antenatal Dexamethasone in Late Preterm Period on Neonatal Hypoglycemia: A Prospective Cohort Study from a Developing Country"],"prefix":"10.1093","volume":"68","author":[{"given":"Somnath","family":"Pal","sequence":"first","affiliation":[{"name":"Department of Neonatology, IPGME&R, Kolkata 700020, 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