{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T04:32:49Z","timestamp":1766377969286,"version":"3.41.2"},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2022,4,5]],"date-time":"2022-04-05T00:00:00Z","timestamp":1649116800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,4,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>In modern society, scurvy is well known in its historical perspective rather than clinical relevance. Scurvy is classically thought to manifest with signs of \u2018bleeding painful gums\u2019 in the undernourished. Little is known regarding its ability to mimic a wide range of rheumatological, orthopaedic, neurological and haematological illnesses. Due to the rarity of its occurrence, there is a poor understanding among present-day clinicians, and so scurvy can easily deceive the uninitiated. We report a school-aged boy with normal neurodevelopment who presented with lower limb pain and difficulty in walking. He was seen by multiple specialist doctors before the clinical diagnosis of scurvy was made by a general paediatrician. Investigations showed that this child had X-ray changes typical of scurvy with low serum ascorbic acid levels. On supplementation with vitamin C, he showed dramatic improvement in symptoms and gradually achieved complete recovery.<\/jats:p>","DOI":"10.1093\/tropej\/fmac029","type":"journal-article","created":{"date-parts":[[2022,3,26]],"date-time":"2022-03-26T12:08:15Z","timestamp":1648296495000},"source":"Crossref","is-referenced-by-count":10,"title":["Scurvy in Children: The Silent Masquerader"],"prefix":"10.1093","volume":"68","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0303-5706","authenticated-orcid":false,"given":"Swathy","family":"Subhash","sequence":"first","affiliation":[{"name":"Department of Paediatrics, KIMSHEALTH , Trivandrum, Kerala, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanuja Titus","family":"Santosh","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, KIMSHEALTH , Trivandrum, Kerala, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,4,5]]},"reference":[{"key":"2022060705300137600_fmac029-B1","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.bcmd.2019.01.004","article-title":"Scurvy, an old story in a new time: the hematologist's experience","volume":"76","author":"Khalife","year":"2019","journal-title":"Blood Cells Mol Dis"},{"key":"2022060705300137600_fmac029-B2","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1007\/s00247-016-3726-4","article-title":"Modern American scurvy - experience with vitamin C deficiency at a large children's hospital","volume":"47","author":"Golriz","year":"2017","journal-title":"Pediatr Radiol"},{"key":"2022060705300137600_fmac029-B3","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1007\/s11926-015-0503-6","article-title":"Rheumatic manifestations of scurvy","volume":"17","author":"Ferrari","year":"2015","journal-title":"Curr Rheumatol Rep"},{"key":"2022060705300137600_fmac029-B4","doi-asserted-by":"crossref","first-page":"58","DOI":"10.5312\/wjo.v3.i5.58","article-title":"Scurvy: an unusual presentation of cerebral palsy","volume":"3","author":"Gupta","year":"2012","journal-title":"World J Orthop"},{"key":"2022060705300137600_fmac029-B5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/jn\/137.7.1757","article-title":"Plasma vitamin C is inversely related to body mass index and waist circumference but not to plasma adiponectin in nonsmoking adults","volume":"137","author":"Johnston","year":"2007","journal-title":"J Nutr"},{"key":"2022060705300137600_fmac029-B6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0016-5107(97)70250-5","article-title":"Scurvy and the gastrointestinal tract","volume":"45","author":"Schuman","year":"1997","journal-title":"Gastrointest Endosc"},{"key":"2022060705300137600_fmac029-B7","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1186\/s12969-020-00439-4","article-title":"Vitamin C deficiency mimicking inflammatory bone disease of the hand","volume":"18","author":"Liebling","year":"2020","journal-title":"Pediatr Rheumatol Online J"},{"volume-title":"Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids","year":"2000","author":"Institute of Medicine Food and Nutrition Board","key":"2022060705300137600_fmac029-B8"}],"container-title":["Journal of Tropical Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/tropej\/article-pdf\/68\/3\/fmac029\/43965840\/fmac029.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/tropej\/article-pdf\/68\/3\/fmac029\/43965840\/fmac029.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,7]],"date-time":"2022-06-07T05:30:20Z","timestamp":1654579820000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/tropej\/article\/doi\/10.1093\/tropej\/fmac029\/6563640"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,5]]},"references-count":8,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,4,5]]}},"URL":"https:\/\/doi.org\/10.1093\/tropej\/fmac029","relation":{},"ISSN":["0142-6338","1465-3664"],"issn-type":[{"type":"print","value":"0142-6338"},{"type":"electronic","value":"1465-3664"}],"subject":[],"published-other":{"date-parts":[[2022,6,1]]},"published":{"date-parts":[[2022,4,5]]},"article-number":"fmac029"}}