{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:19:20Z","timestamp":1753877960460,"version":"3.41.2"},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2022,6,6]],"date-time":"2022-06-06T00:00:00Z","timestamp":1654473600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/501100001849","name":"Defence Research & Development Organisation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001849","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,6,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>To create a nomogram based on transcutaneous bilirubin values (TCB) in first week of life for term and late preterm (&amp;gt;34\u2009weeks) neonates.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods and design<\/jats:title>\n                  <jats:p>Prospective longitudinal study.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Setting<\/jats:title>\n                  <jats:p>Four tertiary-care teaching hospitals (one each in eastern and southern India, two in northern India) between February 2019 and March 2020.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Participants<\/jats:title>\n                  <jats:p>A total of 2492 term and late preterm (&amp;gt;34\u2009weeks) neonates.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Intervention<\/jats:title>\n                  <jats:p>Bilirubin was measured by transcutaneous bilirubinometer (Drager JM-105, Germany) in all neonates in pre-specified times of the day, 12 hourly every day since birth till discharge between 48 and 72\u2009h, and data were recorded in epochs of 6 hourly intervals. Post-discharge, all neonates were called for review in next 48\u2009h.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Outcome measures<\/jats:title>\n                  <jats:p>Primary\u2014TCB in first week of life. Secondary\u2014factors having significant association with significant hyperbilirubinaemia requiring phototherapy.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Total of 2492 neonates (males 1303 and female 1189), with a total of 14\u00a0162 TCB recordings were analysed and mean hourly bilirubin (TCB) at hourly intervals till 120\u2009h and then daily bilirubin values on Days 6 and 7 were tabulated. We have constructed hour-specific bilirubin nomogram with percentiles as per gestational age in term and near-term Indian neonates till 120\u2009h of life. Amongst the known risk factors, delayed cord clamping, primipara and breastfeeding jaundice had significant association for hyperbilirubinaemia needing phototherapy.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>We have created gestation-specific nomogram of TCB levels in 6 hourly intervals for the first 120 postnatal hours, obtained from a large predominantly breast fed healthy, term and near-term Indian neonates.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/tropej\/fmac047","type":"journal-article","created":{"date-parts":[[2022,6,6]],"date-time":"2022-06-06T13:20:38Z","timestamp":1654521638000},"source":"Crossref","is-referenced-by-count":0,"title":["Gestational Age-Specific Nomogram of Transcutaneous Bilirubin in First 120\u2009h of Life for Term and Late Preterm Indian Neonates"],"prefix":"10.1093","volume":"68","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7938-1798","authenticated-orcid":false,"given":"Subhash Chandra","family":"Shaw","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Army Hospital Research & Referral , New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vandana","family":"Negi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Command Hospital , Lucknow, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vivek","family":"Bhat","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Indian Naval Hospital Ship, Asvini , Mumbai, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashutosh","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Command Hospital , Lucknow, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajneesh K","family":"Joshi","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, Armed Forces Medical College , Pune, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kannan","family":"Venkatnarayan","sequence":"additional","affiliation":[{"name":"National Institution for Transforming India (NITI Aayog) , New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rakesh","family":"Gupta","sequence":"additional","affiliation":[{"name":"Govt Institute of Medical Sciences , Noida, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bishwo Raj Bdr","family":"Kunwar","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Armed Forces Medical College , Pune, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shridhar","family":"Gopalakrishnan","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Armed Forces Medical College , Pune, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6189-1420","authenticated-orcid":false,"given":"Vishal Vishnu","family":"Tewari","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Command Hospital , Panchkula, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Madhuri","family":"Kanitkar","sequence":"additional","affiliation":[{"name":"Vice Chancellor, Maharashtra University of Health Sciences (MUHS) , Nashik, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,6,6]]},"reference":[{"key":"2022060613203207500_fmac047-B1","first-page":"335","volume-title":"Cloherty and Stark\u2019s Manual of Neonatal Care","author":"Stark","year":"2017","edition":"8th edn"},{"key":"2022060613203207500_fmac047-B2","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1542\/peds.114.1.297","article-title":"Management of hyperbilirubinemia in 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