{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:19:56Z","timestamp":1753877996388,"version":"3.41.2"},"reference-count":33,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2022,6,6]],"date-time":"2022-06-06T00:00:00Z","timestamp":1654473600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Ethics Committee"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,6,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Aims<\/jats:title>\n                  <jats:p>The influenza virus is an infectious disease with acute respiratory tract infections, caused secondary bacterial infections and death. In this study, we aimed to determine which predictors were associated with the need for high-flow nasal cannula oxygen therapy (HFNC) and transition to intensive care for influenza virus and also to compare single viral pathogens with multiple ones.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Inpatients under the age of 5 with influenza virus-related respiratory tract infections between November 2015 and March 2019 were included in the study. Demographic features, comorbidities, symptoms, secondary bacterial infection, need for HFNC and pediatric intensive care unit and respiratory support system, length of hospital stay, polymerase chain reaction tests were recorded.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A total of 93 patients were included in the study. It was determined that 53.8% of the cases were male and 84.9% were under the age of 2. Comorbidities were present in 50.5% of the cases. Secondary bacterial pneumonia developed in 56.9% of the cases. Patients with secondary bacterial pneumonia had higher PICU need, HFNC need and hospital stay (p\u2009=\u20090.014, p \u2264 0.001 and p \u2264 0.001, respectively). Patients with comorbidity had longer hospital stays and a higher need for HFNC (p \u2264 0.001 and p\u2009=\u20090.001, respectively).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>In this study, it was determined that especially comorbidity and secondary bacterial infection aggravated the clinical treatment of hospitalized patients. Therefore, it was concluded that patients with comorbidity should be followed closely and secondary bacterial pneumonia should be recognized and treated early.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/tropej\/fmac049","type":"journal-article","created":{"date-parts":[[2022,6,25]],"date-time":"2022-06-25T14:13:04Z","timestamp":1656166384000},"source":"Crossref","is-referenced-by-count":0,"title":["Characteristics and Results of Hospital Admission Caused by Influenza Virus Infections in Children under 5 Years Old"],"prefix":"10.1093","volume":"68","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3297-7476","authenticated-orcid":false,"given":"\u00d6zlem","family":"\u00dcz\u00fcm","sequence":"first","affiliation":[{"name":"Department of Pediatric Diseases, Tepecik Training and Research Hospital, University of Health Sciences , Izmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eda","family":"Karada\u011f \u00d6ncel","sequence":"additional","affiliation":[{"name":"Department of Pediatric Infectious Diseases, Tepecik Training and Research Hospital, University of Health Sciences , Izmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yavuz","family":"Demir\u00e7elik","sequence":"additional","affiliation":[{"name":"Department of Pediatric Diseases, Tepecik Training and Research Hospital, University of Health Sciences , Izmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hacer","family":"\u00d6rsdemir Hortu","sequence":"additional","affiliation":[{"name":"Department of Pediatric Diseases, Tepecik Training and Research Hospital, University of Health Sciences , Izmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Kan\u0131k","sequence":"additional","affiliation":[{"name":"Department of Pediatric Diseases, Faculty of Medicine, Katip \u00c7elebi University , Izmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kay\u0131","family":"Elia\u00e7\u0131k","sequence":"additional","affiliation":[{"name":"Department of Pediatric Diseases, Tepecik Training and Research Hospital, University of Health Sciences , Izmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dilek","family":"Y\u0131lmaz \u00c7iftdo\u011fan","sequence":"additional","affiliation":[{"name":"Department of Pediatric Infectious Diseases, Faculty of Medicine, Katip \u00c7elebi University , Izmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet","family":"Helvac\u0131","sequence":"additional","affiliation":[{"name":"Department of Pediatric Diseases, Tepecik Training and Research Hospital, University of Health Sciences , Izmir, 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