{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T01:48:33Z","timestamp":1774921713681,"version":"3.50.1"},"reference-count":11,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2023,4,5]],"date-time":"2023-04-05T00:00:00Z","timestamp":1680652800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,4,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>This study aimed to detect the frequency of Cryptosporidium infection and associated risk factors among children from rural areas in Peru. A case\u2013control study was conducted, nested in a cohort in two rural communities that included children between 6 and 13\u2009months who were followed for 6 months. Cases were children whose fecal samples tested positive for Cryptosporidium infection using an immunochromatography test. Logistic regression was used to calculate odds ratios (ORs) and 95% confidence intervals (CIs) to analyze risk factors associated with Cryptosporidium infection. Among 72 children, 13 (18%) were cases. Cryptosporidium infection was associated with below secondary education of the mother (OR 7.62, 95% CI 1.50\u201336.72) and with having more siblings living at home (OR 1.71, 95% CI 1.04\u20132.82). An important frequency of Cryptosporidium infection among children from rural areas in Peru was reported, more research is needed to understand its true burden and risk factors among children in Peru.<\/jats:p>","DOI":"10.1093\/tropej\/fmad021","type":"journal-article","created":{"date-parts":[[2023,7,19]],"date-time":"2023-07-19T02:45:28Z","timestamp":1689734728000},"source":"Crossref","is-referenced-by-count":3,"title":["<i>Cryptosporidium<\/i> infection and associated risk factors among children from rural areas in Peru: a nested case\u2013control study"],"prefix":"10.1093","volume":"69","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0547-1376","authenticated-orcid":false,"given":"Jose Luis","family":"Paredes","sequence":"first","affiliation":[{"name":"Instituto de Medicina Tropical \u201cAlexander von Humboldt\u201d, Universidad Peruana Cayetano Heredia , Lima, Peru"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafaella","family":"Navarro","sequence":"additional","affiliation":[{"name":"Instituto de Medicina Tropical \u201cAlexander von Humboldt\u201d, Universidad Peruana Cayetano Heredia , Lima, Peru"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Durand","sequence":"additional","affiliation":[{"name":"Instituto de Medicina Tropical \u201cAlexander von Humboldt\u201d, Universidad Peruana Cayetano Heredia , Lima, Peru"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theresa Jean","family":"Ochoa","sequence":"additional","affiliation":[{"name":"Instituto de Medicina Tropical \u201cAlexander von Humboldt\u201d, Universidad Peruana Cayetano Heredia , Lima, Peru"},{"name":"School of Public Health, University of Texas Health Science Center at Houston , Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2023,7,18]]},"reference":[{"key":"2023071902382837400_fmad021-B1","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1016\/S1473-3099(18)30362-1","article-title":"Estimates of the global, regional, and national morbidity, mortality, and aetiologies of diarrhoea in 195 countries: a systematic analysis for the Global Burden of Disease Study 2016","volume":"18","author":"Troeger","year":"2018","journal-title":"Lancet Infect Dis"},{"key":"2023071902382837400_fmad021-B2","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/S0140-6736(13)60844-2","article-title":"Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study","volume":"382","author":"Kotloff","year":"2013","journal-title":"Lancet"},{"key":"2023071902382837400_fmad021-B3","doi-asserted-by":"crossref","first-page":"882","DOI":"10.2478\/s11686-020-00230-1","article-title":"Prevalence of Cryptosporidium infection in the global population: a systematic review and meta-analysis","volume":"65","author":"Dong","year":"2020","journal-title":"Acta Parasit"},{"key":"2023071902382837400_fmad021-B4","doi-asserted-by":"crossref","first-page":"e758","DOI":"10.1016\/S2214-109X(18)30283-3","article-title":"Morbidity, mortality, and long-term consequences associated with diarrhoea from Cryptosporidium infection in children younger than 5 years: a meta-analyses study","volume":"6","author":"Khalil","year":"2018","journal-title":"Lancet Glob Health"},{"key":"2023071902382837400_fmad021-B5","doi-asserted-by":"crossref","first-page":"e0006553","DOI":"10.1371\/journal.pntd.0006553","article-title":"Risk factors for Cryptosporidium infection in low and middle income countries: a systematic review and meta-analysis. Ajjampur SS, editor","volume":"12","author":"Bouzid","year":"2018","journal-title":"PLoS Negl Trop Dis"},{"key":"2023071902382837400_fmad021-B6","doi-asserted-by":"crossref","first-page":"739","DOI":"10.17843\/rpmesp.2016.334.2560","article-title":"Coccidiosis intestinal en ni\u00f1os admitidos en un hospital de Per\u00fa y comparaci\u00f3n de dos m\u00e9todos para la detecci\u00f3n del Cryptosporidium spp","volume":"33","author":"Silva-D\u00edaz","year":"2016","journal-title":"Rev Peru Med Exp Salud Publica"},{"key":"2023071902382837400_fmad021-B7","doi-asserted-by":"crossref","DOI":"10.1093\/cid\/ciy355","article-title":"Epidemiology and risk factors for cryptosporidiosis in children from 8 low-income sites: results from the MAL-ED study","author":"Korpe","year":"2018","journal-title":"Clin Infect Dis"},{"key":"2023071902382837400_fmad021-B8","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.4269\/ajtmh.18-0975","article-title":"Stunting is preceded by intestinal mucosal damage and microbiome changes and is associated with systemic inflammation in a cohort of peruvian infants","volume":"101","author":"Zambruni","year":"2019","journal-title":"Am J Trop Med Hyg"},{"key":"2023071902382837400_fmad021-B9","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.eimc.2010.09.005","article-title":"Evaluaci\u00f3n de dos m\u00e9todos inmunocromatogr\u00e1ficos comerciales para el diagn\u00f3stico r\u00e1pido de Giardia duodenalis y Cryptosporidium spp. en muestras de heces","volume":"29","author":"Guti\u00e9rrez-Cisneros","year":"2011","journal-title":"Enferm Infecc Microbiol Clin"},{"key":"2023071902382837400_fmad021-B10","doi-asserted-by":"crossref","first-page":"867","DOI":"10.4314\/ejhs.v30i6.3","article-title":"Asymptomatic intestinal parasitic infestations among children under five years in selected communities in the Ho Municipality, Ghana","volume":"30","author":"Kpene","year":"2020","journal-title":"Ethiop J Health Sci"},{"key":"2023071902382837400_fmad021-B11","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1093\/cid\/cir807","article-title":"Contribution of enteric infection, altered intestinal barrier function, and maternal malnutrition to infant malnutrition in Bangladesh","volume":"54","author":"Mondal","year":"2012","journal-title":"Clin Infect Dis"}],"container-title":["Journal of Tropical Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/tropej\/article-pdf\/69\/3\/fmad021\/50909126\/fmad021.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/tropej\/article-pdf\/69\/3\/fmad021\/50909126\/fmad021.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,19]],"date-time":"2023-07-19T02:45:34Z","timestamp":1689734734000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/tropej\/article\/doi\/10.1093\/tropej\/fmad021\/7226217"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,5]]},"references-count":11,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,4,5]]}},"URL":"https:\/\/doi.org\/10.1093\/tropej\/fmad021","relation":{},"ISSN":["0142-6338","1465-3664"],"issn-type":[{"value":"0142-6338","type":"print"},{"value":"1465-3664","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,6,1]]},"published":{"date-parts":[[2023,4,5]]},"article-number":"fmad021"}}