{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T11:19:08Z","timestamp":1788175148297,"version":"build-2803163510"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2024,10,4]],"date-time":"2024-10-04T00:00:00Z","timestamp":1728000000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,10,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Recent evidence shows a shift in neonatal mortality causes, with an increasing proportion due to birth defects. This study aimed to determine the prevalence and treatment outcomes of congenital anomalies (CAs) at a tertiary referral center in Northern India. This retrospective observational study was conducted over 7 years (May 2014\u2013December 2021) and included all inborn and outborn neonates admitted with a diagnosis of CA as per ICD-10 classification in a level 3 NICU in North India. The prevalence of CAs was 8.9% (332 out of 3734 neonates). The most commonly affected systems were cardiovascular (33.4%), gastrointestinal (19.8%), and genitourinary (19.8%). While 57.5% of these defects could potentially be addressed through pediatric and cardiovascular surgery, only a small proportion of eligible neonates received timely surgical intervention due to delayed referrals and financial constraints. The mortality rate was 16.8%. This study highlights the significant burden of CAs in Northern India, emphasizing the need for enhanced capacity building, better facilities, and increased awareness for timely referrals. The findings underscore the importance of multidisciplinary collaborations and upgraded healthcare services to inspire further research and preventive strategies to mitigate birth defects. Given the context of a low- and middle-income country, this study\u2019s insights into the prevalence, challenges, and outcomes of CAs are particularly relevant, highlighting the necessity of accessible and affordable healthcare solutions in such settings.<\/jats:p>","DOI":"10.1093\/tropej\/fmae038","type":"journal-article","created":{"date-parts":[[2024,10,15]],"date-time":"2024-10-15T07:58:15Z","timestamp":1728979095000},"source":"Crossref","is-referenced-by-count":4,"title":["Epidemiology and management of congenital anomalies in neonates in a hospital in Northern India"],"prefix":"10.1093","volume":"70","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-0274-0897","authenticated-orcid":false,"given":"Akanksha","family":"Verma","sequence":"first","affiliation":[{"name":"Department of Neonatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences , Lucknow, Uttar Pradesh, 226014,","place":["India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manoj K","family":"Verma","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences , Lucknow, Uttar Pradesh, 226014,","place":["India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vallepu L","family":"Priyanka","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences , Lucknow, Uttar Pradesh, 226014,","place":["India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8659-7658","authenticated-orcid":false,"given":"Kirti","family":"Naranje","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences , Lucknow, Uttar Pradesh, 226014,","place":["India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anita","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences , Lucknow, Uttar Pradesh, 226014,","place":["India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhijeet","family":"Roy","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences , Lucknow, Uttar Pradesh, 226014,","place":["India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhishek","family":"Paul","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences , Lucknow, Uttar Pradesh, 226014,","place":["India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shubha","family":"Phadke","sequence":"additional","affiliation":[{"name":"Department of Medical Genetics, Sanjay Gandhi Postgraduate Institute of Medical Sciences , Lucknow, Uttar Pradesh, 226014,","place":["India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Basant","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgical Superspecialties, Sanjay Gandhi Postgraduate Institute of Medical Sciences , Lucknow, Uttar Pradesh, 226014,","place":["India"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,10,14]]},"reference":[{"key":"2024101507575711600_fmae038-B1","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1016\/S0140-6736(21)01207-1","article-title":"Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burden of Disease study 2019","volume":"398","author":"GBD 2019 Under-5 Mortality 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