{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T07:23:23Z","timestamp":1770881003112,"version":"3.50.1"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2025,2,28]],"date-time":"2025-02-28T00:00:00Z","timestamp":1740700800000},"content-version":"vor","delay-in-days":23,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Foundation for Paediatric Research, Academy of Finland","award":["314450"],"award-info":[{"award-number":["314450"]}]},{"name":"Foundation for Paediatric Research, Academy of Finland","award":["335788"],"award-info":[{"award-number":["335788"]}]},{"name":"Finnish Brain Foundation, Helsinki University Central Hospital"},{"name":"Sigrid Jus\u00e9lius Foundation, and the Finnish Medical Society Duodecim"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,2,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The aims of this prospective study were to describe feeding difficulties in term infants with perinatal asphyxia and to determine whether the time it takes to achieve full oral feeding correlates with early neurological outcome in a high-income setting. Recruitment included 52 term infants with perinatal asphyxia: 32 without hypoxic-ischaemic encephalopathy (HIE), 9 with mild HIE, and 11 with moderate HIE. The time in days it takes to achieve full oral independent feeding was used as a marker of feeding difficulty. Early neurological outcome was evaluated using neonatal brain magnetic resonance imaging (MRI) and Hammersmith Infant Neurological Examination (HINE) at 3 months. In this cohort, 85% of infants (44\/52) needed short-term assisted feeding after birth. The time it takes to achieve full oral feeding correlated with neonatal brain MRI findings and structured neurological examination results at three months. The time it takes to achieve full oral feeding could be a useful clinical measure to assess neurologic recovery after perinatal asphyxia, especially in low-resource settings.<\/jats:p>","DOI":"10.1093\/tropej\/fmaf012","type":"journal-article","created":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T21:35:11Z","timestamp":1741124111000},"source":"Crossref","is-referenced-by-count":2,"title":["Measuring the time it takes to achieve full oral feeding can be used as a low-resource tool to assess neurologic recovery after perinatal asphyxia"],"prefix":"10.1093","volume":"71","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3900-6429","authenticated-orcid":false,"given":"Anna","family":"Tuiskula","sequence":"first","affiliation":[{"name":"Department of Paediatrics, BABA Centre and Paediatric Research Centre, Children\u2019s Hospital, Helsinki University Hospital and University of Helsinki , Helsinki, 00029,","place":["Finland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8057-6194","authenticated-orcid":false,"given":"Leena","family":"Haataja","sequence":"additional","affiliation":[{"name":"Department of Paediatric Neurology, BABA Centre and Paediatric Research Centre, Children\u2019s Hospital, Helsinki University Hospital and University of Helsinki , Helsinki, 00029,","place":["Finland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6665-9009","authenticated-orcid":false,"given":"Marjo","family":"Mets\u00e4ranta","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, BABA Centre and Paediatric Research Centre, Children\u2019s Hospital, Helsinki University Hospital and University of Helsinki , Helsinki, 00029,","place":["Finland"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,2,27]]},"reference":[{"key":"2025030420303963000_fmaf012-B1","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1038\/pr.2013.206","article-title":"Intrapartum-related neonatal encephalopathy incidence and impairment at regional and global levels for 2010 with trends from 1990","volume":"74(Suppl 1)","author":"Lee","year":"2013","journal-title":"Pediatr Res"},{"key":"2025030420303963000_fmaf012-B2","doi-asserted-by":"publisher","first-page":"100885","DOI":"10.1016\/j.eclinm.2021.100885","article-title":"MRI combined with early clinical variables are excellent outcome predictors for newborn infants undergoing therapeutic hypothermia after perinatal asphyxia","volume":"36","author":"Thoresen","year":"2021","journal-title":"EClinicalMedicine"},{"key":"2025030420303963000_fmaf012-B3","doi-asserted-by":"publisher","first-page":"718","DOI":"10.1089\/bfm.2019.0048","article-title":"Oropharyngeal dysphagia in breastfeeding neonates with hypoxic-ischemic encephalopathy on therapeutic hypothermia","volume":"14","author":"Kr\u00fcger","year":"2019","journal-title":"Breastfeed Med"},{"key":"2025030420303963000_fmaf012-B4","doi-asserted-by":"publisher","first-page":"688","DOI":"10.1016\/j.ejpn.2012.05.001","article-title":"Feeding and communication impairments in infants with central grey matter lesions following perinatal hypoxic-ischaemic injury","volume":"16","author":"Martinez-Biarge","year":"2012","journal-title":"Eur J Paediatr Neurol"},{"key":"2025030420303963000_fmaf012-B5","doi-asserted-by":"publisher","first-page":"1678","DOI":"10.1055\/s-0041-1725161","article-title":"Electroencephalogram background predicts time to full oral feedings in hypoxic-ischemic encephalopathy","volume":"39","author":"Takle","year":"2022","journal-title":"Am J Perinatol"},{"key":"2025030420303963000_fmaf012-B6","doi-asserted-by":"publisher","first-page":"696","DOI":"10.1001\/archneur.1976.00500100030012","article-title":"Neonatal encephalopathy following fetal distress. A clinical and electroencephalographic study","volume":"33","author":"Sarnat","year":"1976","journal-title":"Arch Neurol"},{"key":"2025030420303963000_fmaf012-B7","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1111\/apa.16133","article-title":"Profile of minor neurological findings after perinatal asphyxia","volume":"111","author":"Kivi","year":"2022","journal-title":"Acta Paediatr"},{"key":"2025030420303963000_fmaf012-B8","doi-asserted-by":"publisher","first-page":"599633","DOI":"10.3389\/fped.2020.599633","article-title":"Abnormal nutritive sucking as an indicator of neonatal brain injury","volume":"8","author":"Shandley","year":"2020","journal-title":"Front Pediatr"},{"key":"2025030420303963000_fmaf012-B9","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1038\/s41390-023-02978-4","article-title":"Networks of cortical activity show graded responses to perinatal asphyxia","volume":"96","author":"Syv\u00e4lahti","year":"2024","journal-title":"Pediatr Res"},{"key":"2025030420303963000_fmaf012-B10","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1038\/s41390-024-03235-y","article-title":"Quantitative EEG features during the first day correlate to clinical outcome in perinatal asphyxia","volume":"97","author":"Tuiskula","year":"2025","journal-title":"Pediatr Res"}],"container-title":["Journal of Tropical Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/tropej\/article-pdf\/71\/2\/fmaf012\/62200507\/fmaf012.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/tropej\/article-pdf\/71\/2\/fmaf012\/62200507\/fmaf012.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T21:36:44Z","timestamp":1741124204000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/tropej\/article\/doi\/10.1093\/tropej\/fmaf012\/8045586"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,5]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,2,5]]}},"URL":"https:\/\/doi.org\/10.1093\/tropej\/fmaf012","relation":{},"ISSN":["1465-3664"],"issn-type":[{"value":"1465-3664","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025,4]]},"published":{"date-parts":[[2025,2,5]]},"article-number":"fmaf012"}}