{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T05:18:20Z","timestamp":1788412700806,"version":"build-2803163510"},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2025,8,8]],"date-time":"2025-08-08T00:00:00Z","timestamp":1754611200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,8,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The continuous daily care required by children with congenital Zika syndrome (CZS) may overload the lives of caregivers. However, little is known about the factors associated with musculoskeletal symptoms experienced by caregivers. This study aimed to investigate the prevalence of musculoskeletal symptoms in caregivers of children with CZS and identify its associated factors. This cross-sectional study included caregivers of children with CZS from northeast Brazil. Musculoskeletal symptoms were assessed using the Nordic Musculoskeletal Questionnaire. Information about caregivers, pregnancy, childbirth, general aspects, and neuropsychomotor development of children with CZS were also recorded. Musculoskeletal symptoms of caregivers were analyzed using bivariate analysis and binary logistic regression. We included 41 caregivers, of whom 39 (95.12%) had musculoskeletal symptoms in the last 12\u2009months, and 31 (75.61%) had symptoms in the last 7 days. However, less than half considered these symptoms incapacitating to require the absence from their activities (43.90%) or a medical consultation (26.83%). The presence of symptoms in at least one body region was associated with occupational activities, number of children with or without disability, caregiver age, current head circumference, child age, and ability of the child to sit without support. Musculoskeletal symptoms were not considered incapacitating by caregivers of children with CZS despite its high prevalence. The characteristics of the caregiver and children were associated with the prevalence of musculoskeletal symptoms.<\/jats:p>","DOI":"10.1093\/tropej\/fmaf039","type":"journal-article","created":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T23:55:28Z","timestamp":1758585328000},"source":"Crossref","is-referenced-by-count":1,"title":["The burden of musculoskeletal symptoms in caregivers of children with congenital Zika syndrome: a cross-sectional study"],"prefix":"10.1093","volume":"71","author":[{"given":"Jos\u00e9 Geraldo Ribeiro","family":"Greg\u00f3rio","sequence":"first","affiliation":[{"name":"Health Department, Professor Joaquim Amorim Neto Research Institute (IPESQ) , Campina Grande, Para\u00edba 58406-115,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5514-762X","authenticated-orcid":false,"given":"Thayla Amorim","family":"Santino","sequence":"additional","affiliation":[{"name":"Health Department, Professor Joaquim Amorim Neto Research Institute (IPESQ) , Campina Grande, Para\u00edba 58406-115,","place":["Brazil"]},{"name":"Physical Therapy Department, State University of Para\u00edba (UEPB) , Campina Grande, Para\u00edba, 58429-500,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Girlene","family":"Souza de Azevedo","sequence":"additional","affiliation":[{"name":"Health Department, Professor Joaquim Amorim Neto Research Institute (IPESQ) , Campina Grande, Para\u00edba 58406-115,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-4923-2857","authenticated-orcid":false,"given":"Janiele","family":"de Sales Tavares","sequence":"additional","affiliation":[{"name":"Health Department, Professor Joaquim Amorim Neto Research Institute (IPESQ) , Campina Grande, Para\u00edba 58406-115,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thamyris","family":"de Sales Regis","sequence":"additional","affiliation":[{"name":"Health Department, Professor Joaquim Amorim Neto Research Institute (IPESQ) , Campina Grande, Para\u00edba 58406-115,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jousilene","family":"de Sales Tavares","sequence":"additional","affiliation":[{"name":"Health Department, Professor Joaquim Amorim Neto Research Institute (IPESQ) , Campina Grande, Para\u00edba 58406-115,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7352-6711","authenticated-orcid":false,"given":"Gabriela Lopes","family":"Gama","sequence":"additional","affiliation":[{"name":"Physical Therapy Department, Federal University of Juiz de Fora (UFJF) , Governador Valadares, Minas Gerais, 35020-360,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriana","family":"Melo","sequence":"additional","affiliation":[{"name":"Health Department, Professor Joaquim Amorim Neto Research Institute (IPESQ) , Campina Grande, Para\u00edba 58406-115,","place":["Brazil"]},{"name":"Medicine Department, UNIFACISA University Center , Campina Grande, Para\u00edba, 58408-326,","place":["Brazil"]},{"name":"Medicine Department, Federal University of Campina Grande (UFCG) , Campina Grande, Para\u00edba, 58401-490,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,9,22]]},"reference":[{"key":"2025092303312678800_fmaf039-B1","doi-asserted-by":"crossref","first-page":"242","DOI":"10.15585\/mmwr.mm6509e2","article-title":"Increase in reported prevalence of microcephaly in infants born to women living in areas with confirmed Zika virus transmission during the first trimester of pregnancy\u2013Brazil, 2015","volume":"65","author":"de Oliveira","year":"2016","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"2025092303312678800_fmaf039-B2","doi-asserted-by":"crossref","first-page":"S154","DOI":"10.1542\/peds.2017-2038D","article-title":"Development of infants with congenital Zika syndrome: what do we know and what can we expect?","volume":"141","author":"Wheeler","year":"2018","journal-title":"Pediatrics"},{"key":"2025092303312678800_fmaf039-B3","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1111\/dmcn.14227","article-title":"Motor function in children with congenital Zika syndrome","volume":"62","author":"Melo","year":"2020","journal-title":"Dev Med Child Neurol"},{"key":"2025092303312678800_fmaf039-B4","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1002\/ijgo.13044","article-title":"How do mothers feel? 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