{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T15:59:07Z","timestamp":1767369547573,"version":"3.48.0"},"reference-count":17,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T00:00:00Z","timestamp":1767312000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Mycobacterium bovis (M. bovis), a member of Mycobacterium tuberculosis complex, can cause tuberculosis in both adults and children. Our study aimed to identify the clinical and laboratory features of children with M. bovis infection. This retrospective descriptive study sampled a cohort of consecutive cases diagnosed as M. bovis infection by culture positivity from October 2013 through May 2023. Epidemiological data were obtained on gender, age, region of residence, clinical signs, exposure, treatment, and outcome. The analysis was performed using descriptive statistics. M. bovis was found to be the causative agent in seven of 25 patients with culture-confirmed tuberculosis, but M. bovis mostly caused extrapulmonary disease, the most frequent clinical form being cervical lymphadenitis. The most common symptoms were fever and neck swelling. No resistance was detected, except to pyrazinamide, in the strains. M. bovis has a significant disease burden in children. Advanced typing is recommended for M. tuberculosis complex culture positivity to determine the appropriate treatment regimen.<\/jats:p>","DOI":"10.1093\/tropej\/fmaf046","type":"journal-article","created":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T13:10:46Z","timestamp":1762521046000},"source":"Crossref","is-referenced-by-count":0,"title":["<i>Mycobacterium bovis<\/i>\n                    Infection in Children: A Tertiary Hospital Experience"],"prefix":"10.1093","volume":"72","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1307-0246","authenticated-orcid":false,"given":"Melike","family":"Emiroglu","sequence":"first","affiliation":[{"name":"Division of Pediatric Infectious Diseases, Department of Pediatrics, Selcuk University Faculty of Medicine , 42130 Konya,","place":["Turkey"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3384-769X","authenticated-orcid":false,"given":"Gulsum","family":"Alkan","sequence":"additional","affiliation":[{"name":"Division of Pediatric Infectious Diseases, Department of Pediatrics, Selcuk University Faculty of Medicine , 42130 Konya,","place":["Turkey"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2473-5672","authenticated-orcid":false,"given":"Sadiye Kubra","family":"Tuter Oz","sequence":"additional","affiliation":[{"name":"Division of Pediatric Infectious Diseases, Department of Pediatrics, Selcuk University Faculty of Medicine , 42130 Konya,","place":["Turkey"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0291-4987","authenticated-orcid":false,"given":"Hatice","family":"Turk Dagi","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Selcuk University Faculty of Medicine , 42130 Konya,","place":["Turkey"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2026,1,2]]},"reference":[{"key":"2026010210572988100_fmaf046-B1","first-page":"375","volume-title":"Handbook of Child and Adolescent Tuberculosis","author":"Starke","year":"2016"},{"key":"2026010210572988100_fmaf046-B2","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.tube.2005.05.002","article-title":"Human Mycobacterium bovis infection in the United Kingdom: incidence, risks, control measures and review of the zoonotic aspects of bovine tuberculosis","volume":"86","author":"de la Rua-Domenech","year":"2006","journal-title":"Tuberculosis (Edinb)"},{"key":"2026010210572988100_fmaf046-B3","doi-asserted-by":"publisher","first-page":"377","DOI":"10.3201\/eid2303.161408","article-title":"Epidemiology of Mycobacterium bovis disease in humans in England, Wales, and Northern Ireland, 2002\u20132014","volume":"23","author":"Davidson","year":"2017","journal-title":"Emerg Infect Dis"},{"key":"2026010210572988100_fmaf046-B4","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.3201\/eid1209.060209","article-title":"Mycobacterium bovis infection, Lyon, France","volume":"12","author":"Mignard","year":"2006","journal-title":"Emerg Infect Dis"},{"key":"2026010210572988100_fmaf046-B5","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.vetmic.2016.08.019","article-title":"Molecular and epidemiological population-based integrative analysis of human and animal Mycobacterium bovis infections in a low prevalence setting","volume":"195","author":"Palacios","year":"2016","journal-title":"Vet Microbiol"},{"key":"2026010210572988100_fmaf046-B6","doi-asserted-by":"publisher","first-page":"3035","DOI":"10.1017\/S0950268817001996","article-title":"Five-year surveillance of human tuberculosis caused by Mycobacterium bovis in bologna, Italy: an underestimated problem","volume":"145","author":"Lombardi","year":"2017","journal-title":"Epidemiol Infect"},{"key":"2026010210572988100_fmaf046-B7","doi-asserted-by":"publisher","first-page":"457","DOI":"10.3201\/eid1703.101111","article-title":"Epidemiology of Mycobacterium bovis disease in humans, The Netherlands, 1993-2007","volume":"17","author":"Majoor","year":"2011","journal-title":"Emerg Infect Dis"},{"key":"2026010210572988100_fmaf046-B8","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1086\/589240","article-title":"Human tuberculosis due to Mycobacterium bovis in the United States, 1995-2005","volume":"47","author":"Hlavsa","year":"2008","journal-title":"Clin Infect Dis"},{"key":"2026010210572988100_fmaf046-B9","doi-asserted-by":"publisher","first-page":"594","DOI":"10.1093\/cid\/ciw371","article-title":"Human tuberculosis caused by Mycobacterium bovis in the United States, 2006-2013","volume":"63","author":"Scott","year":"2016","journal-title":"Clin Infect Dis"},{"key":"2026010210572988100_fmaf046-B10","doi-asserted-by":"publisher","first-page":"435","DOI":"10.3201\/eid2103.141539","article-title":"Epidemiology of human Mycobacterium bovis disease, California, USA, 2003-2011","volume":"21","author":"Gallivan","year":"2015","journal-title":"Emerg Infect Dis"},{"key":"2026010210572988100_fmaf046-B11","doi-asserted-by":"publisher","first-page":"3837","DOI":"10.1128\/JCM.01172-11","article-title":"Species distribution of the Mycobacterium tuberculosis complex in clinical isolates from 2007 to 2010 in Turkey: a prospective study","volume":"49","author":"Bayraktar","year":"2011","journal-title":"J Clin Microbiol"},{"key":"2026010210572988100_fmaf046-B12","doi-asserted-by":"publisher","first-page":"392","DOI":"10.5578\/mb.27784","article-title":"D\u00fczce ilinde izole edilen Mycobacterium tuberculosis kompleks su\u015flar\u0131nda Mycobacterium bovis subsp. Bovis varl\u0131\u011f\u0131n\u0131n ara\u015ft\u0131r\u0131lmas\u0131 [investigation of Mycobacterium bovis subsp. bovis among the strains of Mycobacterium tuberculosis complex isolated in d\u00fczce province, Turkey]","volume":"50","author":"\u00d6zt\u00fcrk","year":"2016","journal-title":"Mikrobiyol Bul"},{"key":"2026010210572988100_fmaf046-B13","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1111\/zph.12868","article-title":"Global prevalence of Mycobacterium bovis infections among human tuberculosis cases: systematic review and meta-analysis","volume":"68","author":"Taye","year":"2021","journal-title":"Zoonoses Public Health"},{"key":"2026010210572988100_fmaf046-B14","doi-asserted-by":"publisher","first-page":"e21","DOI":"10.1016\/S1473-3099(16)30139-6","article-title":"Zoonotic tuberculosis in human beings caused by Mycobacterium bovis-a call for action","volume":"17","author":"Olea-Popelka","year":"2017","journal-title":"Lancet Infect Dis"},{"key":"2026010210572988100_fmaf046-B15","doi-asserted-by":"publisher","first-page":"1500","DOI":"10.1183\/13993003.00629-2016","article-title":"Treatment of human disease due to Mycobacterium bovis: a systematic review","volume":"48","author":"Lan","year":"2016","journal-title":"Eur Respir J"},{"key":"2026010210572988100_fmaf046-B16","doi-asserted-by":"publisher","first-page":"S94","DOI":"10.1016\/j.rvsc.2013.11.008","article-title":"Current knowledge, and pending challenges in zoonosis caused by Mycobacterium bovis: a review","volume":"97 Suppl","author":"P\u00e9rez-Lago","year":"2014","journal-title":"Res Vet Sci"},{"key":"2026010210572988100_fmaf046-B17","doi-asserted-by":"publisher","first-page":"909","DOI":"10.3201\/eid1406.071485","article-title":"Tuberculosis from Mycobacterium bovis in binational communities, United States","volume":"14","author":"Rodwell","year":"2008","journal-title":"Emerg Infect Dis"}],"container-title":["Journal of Tropical Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/tropej\/article-pdf\/72\/1\/fmaf046\/66210472\/fmaf046.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/tropej\/article-pdf\/72\/1\/fmaf046\/66210472\/fmaf046.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T15:57:39Z","timestamp":1767369459000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/tropej\/article\/doi\/10.1093\/tropej\/fmaf046\/8408545"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,2]]},"references-count":17,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1,2]]}},"URL":"https:\/\/doi.org\/10.1093\/tropej\/fmaf046","relation":{},"ISSN":["0142-6338","1465-3664"],"issn-type":[{"value":"0142-6338","type":"print"},{"value":"1465-3664","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,2]]},"published":{"date-parts":[[2026,1,2]]},"article-number":"fmaf046"}}