{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T13:31:29Z","timestamp":1759411889869},"reference-count":23,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2019,5,12]],"date-time":"2019-05-12T00:00:00Z","timestamp":1557619200000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The safety of two kinds of post-marketing enterovirus 71 (EV71) vaccine in China was evaluated in this study. Fourteen vaccination clinics were randomly assigned in a 1:1 ratio, and both children in two groups were administered according to a two-dose schedule (on a 0 and 28\u2009day schedule). Written informed consent was obtained, and recipients in this study were observed for 30\u2009min after inoculation in the clinic, and then followed via phone or on-site follow-up at day 3 and 30. No severe EV71-associated adverse event was reported. No significant difference was noticed between Group Sinovac and Group CAMS (\u03c7z\u2009=\u20090.346, p\u2009=\u20090.556). There was no significant difference in the occurrence of adverse events among recipients aged less than 24\u2009months; however, the proportion of adverse events was higher in Group CAMS than in Group Sinovac among the subjects aged 24\u201335\u2009months (5.3% vs. 2.5%, p\u2009&lt;\u20090.001). The two kinds of EV71 vaccines showed satisfactory safety. Adverse events after vaccination were normal and acceptable.<\/jats:p>","DOI":"10.1093\/tropej\/fmz004","type":"journal-article","created":{"date-parts":[[2019,4,9]],"date-time":"2019-04-09T11:09:47Z","timestamp":1554808187000},"page":"547-551","source":"Crossref","is-referenced-by-count":5,"title":["Safety Comparison of Two Enterovirus 71 (EV71) Inactivated Vaccines in Yiwu, China"],"prefix":"10.1093","volume":"65","author":[{"given":"Shuying","family":"Luo","sequence":"first","affiliation":[{"name":"Division of Planned Immunization, Yiwu Center for Disease Prevention and Control, Zhejiang Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fei","family":"Wu","sequence":"additional","affiliation":[{"name":"Division of Planned Immunization, Yiwu Center for Disease Prevention and Control, Zhejiang Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaojun","family":"Ye","sequence":"additional","affiliation":[{"name":"Division of Planned Immunization, Yiwu Center for Disease Prevention and Control, Zhejiang Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tao","family":"Fu","sequence":"additional","affiliation":[{"name":"Division of Planned Immunization, Yiwu Center for Disease Prevention and Control, Zhejiang Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingbo","family":"Tao","sequence":"additional","affiliation":[{"name":"Division of Planned Immunization, Yiwu Center for Disease Prevention and Control, Zhejiang Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weibiao","family":"Luo","sequence":"additional","affiliation":[{"name":"Division of Planned Immunization, Yiwu Center for Disease Prevention and Control, Zhejiang Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Wang","sequence":"additional","affiliation":[{"name":"Division of Planned Immunization, Yiwu Center for Disease Prevention and Control, Zhejiang Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianwei","family":"Jia","sequence":"additional","affiliation":[{"name":"Division of Planned Immunization, Yiwu Center for Disease Prevention and Control, Zhejiang Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lingqiao","family":"Lou","sequence":"additional","affiliation":[{"name":"Division of Planned Immunization, Yiwu Center for Disease Prevention and Control, Zhejiang Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2019,5,11]]},"reference":[{"key":"2019112308003125800_fmz004-B1","doi-asserted-by":"crossref","first-page":"e25662","DOI":"10.1371\/journal.pone.0025662","article-title":"The persistent circulation of enterovirus 71 in People\u2019s Republic of China: causing emerging nationwide epidemics since 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