{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T19:27:41Z","timestamp":1790105261827,"version":"4.0.1"},"reference-count":57,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2019,4,21]],"date-time":"2019-04-21T00:00:00Z","timestamp":1555804800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Ministry of Health, Rome","award":["3C04\/1"],"award-info":[{"award-number":["3C04\/1"]}]},{"name":"Esther-Italy, Ministry of Health","award":["9M34"],"award-info":[{"award-number":["9M34"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>HIV-exposed uninfected (HEU) infants show a high rate of morbidity. We aimed to investigate on biomarkers of immune activation\/microbial translocation in HEU infants, evaluating the impact that infections\/malnutrition can have on biomarker levels during the first year of life.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Clinical data of 72 Malawian infants were recorded monthly and correlated with levels of soluble CD14 (sCD14), lipopolysaccharide-binding protein (LBP) and intestinal fatty acid-binding protein (I-FABP), analyzed longitudinally.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Levels of sCD14 and LBP showed a significant age-related increase. Higher levels of LBP (19.4 vs. 15.2\u2009\u03bcg\/ml) were associated with stunting, affecting 30% of the infants. The association remained statistically significant after adjusting for cytomegalovirus acquisition, malaria and respiratory infections (p\u2009=\u20090.031). I-FABP levels were significantly increased in infants experiencing gastrointestinal infections (1442.8 vs. 860.0\u2009pg\/ml, p\u2009=\u20090.018).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>We provide evidence that stunting is associated with an enhanced inflammatory response to microbial products in HEU children, suggesting that malnutrition status should be taken into consideration to better understand the alteration of the immune profile of HEU infants living in poor socioeconomic settings.<\/jats:p><\/jats:sec>","DOI":"10.1093\/tropej\/fmz022","type":"journal-article","created":{"date-parts":[[2019,3,27]],"date-time":"2019-03-27T20:47:32Z","timestamp":1553719652000},"page":"617-625","source":"Crossref","is-referenced-by-count":10,"title":["Immune Activation and Microbial Translocation Markers in HIV-Exposed Uninfected Malawian Infants in the First Year of Life"],"prefix":"10.1093","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2050-9037","authenticated-orcid":false,"given":"Silvia","family":"Baroncelli","sequence":"first","affiliation":[{"name":"National Center for Global Health, Istituto Superiore di Sanit\u00e0, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clementina Maria","family":"Galluzzo","sequence":"additional","affiliation":[{"name":"National Center for Global Health, Istituto Superiore di Sanit\u00e0, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Liotta","sequence":"additional","affiliation":[{"name":"Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mauro","family":"Andreotti","sequence":"additional","affiliation":[{"name":"National Center for Global Health, Istituto Superiore di Sanit\u00e0, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandro","family":"Mancinelli","sequence":"additional","affiliation":[{"name":"Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Mphwere","sequence":"additional","affiliation":[{"name":"DREAM Program, Community of S. Egidio, Blantyre, Malawi"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enok","family":"Bokola","sequence":"additional","affiliation":[{"name":"DREAM Program, Community of S. Egidio, Blantyre, Malawi"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberta","family":"Amici","sequence":"additional","affiliation":[{"name":"National Center for Global Health, Istituto Superiore di Sanit\u00e0, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Cristina","family":"Marazzi","sequence":"additional","affiliation":[{"name":"Department of Human Sciences, LUMSA University, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonardo","family":"Palombi","sequence":"additional","affiliation":[{"name":"Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucia","family":"Palmisano","sequence":"additional","affiliation":[{"name":"National Center for Drug Research and Evaluation, Istituto Superiore di Sanit\u00e0, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Giuliano","sequence":"additional","affiliation":[{"name":"National Center for Global Health, Istituto Superiore di Sanit\u00e0, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2019,4,21]]},"reference":[{"key":"2019112308003056400_fmz022-B1","volume-title":"AIDSinfo. Regional Factsheet Section","year":"2017"},{"key":"2019112308003056400_fmz022-B2","doi-asserted-by":"crossref","first-page":"e47337","DOI":"10.1371\/journal.pone.0047337","article-title":"Mortality and health outcomes of HIV-exposed and unexposed children in a PMTCT cohort in Malawi","volume":"7","author":"Landes","year":"2012","journal-title":"PLoS One"},{"key":"2019112308003056400_fmz022-B3","doi-asserted-by":"crossref","first-page":"81","DOI":"10.3851\/IMP1991","article-title":"Treating HIV-infected mothers reduces under 5 years of age mortality rates to levels seen in children of HIV-uninfected mothers in rural South Africa","volume":"17","author":"Ndirangu","year":"2012","journal-title":"Antivir Ther"},{"key":"2019112308003056400_fmz022-B4","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1111\/cei.12251","article-title":"HIV-exposed uninfected children: a growing population with a vulnerable immune system?","volume":"176","author":"Afran","year":"2014","journal-title":"Clin Exp Immunol"},{"key":"2019112308003056400_fmz022-B5","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1111\/tmi.12695","article-title":"Mortality risk and associated factors in HIV-exposed, uninfected children","volume":"21","author":"Arikawa","year":"2016","journal-title":"Trop Med Int Health"},{"key":"2019112308003056400_fmz022-B6","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1093\/tropej\/fms019","article-title":"HIV-exposed uninfected infants are at increased risk for severe infections in the first year of life","volume":"58","author":"Slogrove","year":"2012","journal-title":"J Trop Pediatr"},{"key":"2019112308003056400_fmz022-B7","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1093\/cid\/civ059","article-title":"Increased risk for and mortality from invasive pneumococcal disease in HIV-exposed but uninfected infants aged <1 year in South Africa, 2009-2013","volume":"60","author":"von Mollendorf","year":"2015","journal-title":"Clin Infect Dis"},{"key":"2019112308003056400_fmz022-B8","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1001\/jama.2011.100","article-title":"Maternal HIV infection and antibody responses against vaccine-preventable diseases in uninfected infants","volume":"305","author":"Jones","year":"2011","journal-title":"JAMA"},{"key":"2019112308003056400_fmz022-B9","doi-asserted-by":"crossref","first-page":"338.","DOI":"10.3389\/fimmu.2016.00338","article-title":"Transfer of maternal antimicrobial immunity to HIV-exposed uninfected newborns","volume":"7","author":"Abu-Raya","year":"2016","journal-title":"Front Immunol"},{"key":"2019112308003056400_fmz022-B10","doi-asserted-by":"crossref","first-page":"1406","DOI":"10.1128\/CVI.05065-11","article-title":"Impaired humoral response to vaccines among HIV-exposed uninfected infants","volume":"18","author":"Abramczuk","year":"2011","journal-title":"Clin Vaccine Immunol"},{"key":"2019112308003056400_fmz022-B11","doi-asserted-by":"crossref","first-page":"2042","DOI":"10.1016\/j.vaccine.2013.02.044","article-title":"Reduced Poliovirus vaccine neutralising-antibody titres in infants with maternal HIV-exposure","volume":"31","author":"Sanz-Ramos","year":"2013","journal-title":"Vaccine"},{"key":"2019112308003056400_fmz022-B12","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1111\/j.1365-2567.2009.03186.x","article-title":"Human immunodeficiency virus (HIV) infection during pregnancy induces CD4 T-cell differentiation and modulates responses to Bacille Calmette-Guerin (BCG) vaccine in HIV-uninfected infants","volume":"129","author":"Miles","year":"2010","journal-title":"Immunology"},{"key":"2019112308003056400_fmz022-B13","doi-asserted-by":"crossref","DOI":"10.1097\/INF.0b013e31821d141e","article-title":"Increased microbial translocation in \u2264180 days old perinatally human immunodeficiency virus-positive infants as compared with human immunodeficiency virus-exposed uninfected infants of similar age","volume":"30","author":"Papasavvas","year":"2011","journal-title":"Pediatr Infect Dis J"},{"key":"2019112308003056400_fmz022-B14","doi-asserted-by":"crossref","first-page":"470","DOI":"10.3389\/fimmu.2017.00470","article-title":"Altered natural killer cell function in HIV-exposed uninfected infants","volume":"8","author":"Smith","year":"2017","journal-title":"Front Immunol"},{"key":"2019112308003056400_fmz022-B15","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1182\/blood.V98.2.398","article-title":"Impaired progenitor cell function in HIV-negative infants of HIV-positive mothers results in decreased thymic output and low CD4 counts","volume":"98","author":"Nielsen","year":"2001","journal-title":"Blood"},{"key":"2019112308003056400_fmz022-B16","doi-asserted-by":"crossref","first-page":"e92","DOI":"10.1016\/S1473-3099(16)00055-4","article-title":"HIV-exposed, uninfected infants: new global challenges in the era of paediatric HIV elimination","volume":"16","author":"Evans","year":"2016","journal-title":"Lancet Infect Dis"},{"key":"2019112308003056400_fmz022-B17","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1097\/QAI.0000000000000161","article-title":"Altered innate immune development in HIV-exposed uninfected infants","volume":"66","author":"Reikie","year":"2014","journal-title":"J Acquir Immune Defic Syndr"},{"key":"2019112308003056400_fmz022-B18","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1038\/nm1511","article-title":"Microbial translocation is a cause of systemic immune activation in chronic HIV infection","volume":"12","author":"Brenchley","year":"2006","journal-title":"Nat Med"},{"key":"2019112308003056400_fmz022-B19","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1097\/QAI.0b013e31829a2f12","article-title":"Correlation between different methods to measure microbial translocation and its association with immune activation in long-term suppressed HIV-1-infected individuals","volume":"64","author":"Abad-Fern\u00e1ndez","year":"2013","journal-title":"J Acquir Immune Defic Syndr"},{"key":"2019112308003056400_fmz022-B20","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1172\/JCI59011","article-title":"Altered CD4+ T cell homing to the gut impairs mucosal immune reconstitution in treated HIV-infected individuals","volume":"122","author":"Mavigner","year":"2012","journal-title":"J Clin Invest"},{"key":"2019112308003056400_fmz022-B21","doi-asserted-by":"crossref","first-page":"e68950","DOI":"10.1371\/journal.pone.0068950","article-title":"Maternal antiretroviral therapy for the prevention of mother-to-child transmission of HIV in Malawi: maternal and infant outcomes two years after delivery","volume":"8","author":"Giuliano","year":"2013","journal-title":"PLoS One"},{"key":"2019112308003056400_fmz022-B22","volume-title":"Handbook: IMCI Integrated Management of Childhood Illness","year":"2005"},{"key":"2019112308003056400_fmz022-B23","volume-title":"Division of AIDS Table for Grading the Severity of Adult and Pediatric Adverse Events, version 1.0","year":"2004"},{"key":"2019112308003056400_fmz022-B24","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1007\/s00430-016-0478-6","article-title":"CMV infection in a cohort of HIV-exposed infants born to mothers receiving antiretroviral therapy during pregnancy and breastfeeding","volume":"206","author":"Pirillo","year":"2017","journal-title":"Med Microbiol Immunol"},{"key":"2019112308003056400_fmz022-B25","doi-asserted-by":"crossref","DOI":"10.1093\/oso\/9780195171693.001.0001","volume-title":"Principles of Nutritional Assessment","author":"Gibson","year":"2005"},{"key":"2019112308003056400_fmz022-B26","year":"2009"},{"key":"2019112308003056400_fmz022-B27","volume-title":"WHO Multicentre Growth Reference Study Group. WHO Child Growth Standards: Methods and Development: Length\/Height-for-Age, Weight-for-Age, Weight-for-Length, Weight-for-Height and Body Mass Index-for-Age","year":"2006"},{"key":"2019112308003056400_fmz022-B28","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1111\/eci.12132","article-title":"Training innate immunity: the changing concept of immunological memory in innate host defence","volume":"43","author":"Netea","year":"2013","journal-title":"Eur J Clin Invest"},{"key":"2019112308003056400_fmz022-B29","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/S1473-3099(11)70341-3","article-title":"Uninfected but not unaffected: chronic maternal infections during pregnancy, fetal immunity, and susceptibility to postnatal infections","volume":"12","author":"Dauby","year":"2012","journal-title":"Lancet Infect Dis"},{"key":"2019112308003056400_fmz022-B30","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1016\/j.it.2015.09.009","article-title":"Impact of early-life exposures on immune maturation and susceptibility to disease","volume":"36","author":"Gollwitzer","year":"2015","journal-title":"Trends Immunol"},{"key":"2019112308003056400_fmz022-B31","doi-asserted-by":"crossref","first-page":"e11523.","DOI":"10.1371\/journal.pone.0011523","article-title":"Early life disease programming during the preconception and prenatal period: making the link between stressful life events and type-1 diabetes","volume":"5","author":"Virk","year":"2010","journal-title":"PLoS ONE"},{"key":"2019112308003056400_fmz022-B32","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1111\/j.1399-3038.2012.01346.x","article-title":"Foetal exposure to maternal stressful events increases the risk of having asthma and atopic diseases in childhood","volume":"23","author":"de Marco","year":"2012","journal-title":"Pediatr Allergy Immunol"},{"key":"2019112308003056400_fmz022-B33","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1097\/MOG.0b013e32835955d3","article-title":"Maternal farm exposure\/ingestion of unpasteurized cow's milk and allergic disease","volume":"28","author":"von Mutius","year":"2012","journal-title":"Curr Opin Gastroenterol"},{"key":"2019112308003056400_fmz022-B34","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1186\/s12879-015-0766-6","article-title":"Impact of elevated maternal HIV viral load at delivery on T-cell populations in HIV exposed uninfected infants in Mozambique","volume":"15","author":"de Deus","year":"2015","journal-title":"BMC Infect Dis"},{"key":"2019112308003056400_fmz022-B35","doi-asserted-by":"crossref","first-page":"236.","DOI":"10.1186\/1471-2334-14-236","article-title":"Impact of maternal HIV-1 viremia on lymphocyte subsets among HIV-exposed uninfected infants: protective mechanism or immunodeficiency","volume":"14","author":"Kakkar","year":"2014","journal-title":"BMC Infect Dis"},{"key":"2019112308003056400_fmz022-B36","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1093\/infdis\/jit221","article-title":"Role of intestinal mucosal integrity in HIV transmission to infants through breast-feeding: the BAN study","volume":"208","author":"Kourtis","year":"2013","journal-title":"J Infect Dis"},{"key":"2019112308003056400_fmz022-B37","article-title":"Initiation of anti-retroviral therapy before pregnancy reduces the risk of infection-related hospitalization in HIV-exposed uninfected infants born in a high-income country","author":"Goetghebuer","year":"2018","journal-title":"Clin Infect Dis"},{"key":"2019112308003056400_fmz022-B38","doi-asserted-by":"crossref","first-page":"4580","DOI":"10.1046\/j.1432-1327.2001.02385.x","article-title":"Essential roles of CD14 and lipopolysaccharide-binding protein for activation of toll-like receptor (TLR)2 as well as TLR4 Reconstitution of TLR2- and TLR4-activation by distinguishable ligands in LPS preparations","volume":"268","author":"Muta","year":"2001","journal-title":"Eur J Biochem"},{"key":"2019112308003056400_fmz022-B39","doi-asserted-by":"crossref","first-page":"e86928.","DOI":"10.1371\/journal.pone.0086928","article-title":"Stunting is characterized by chronic inflammation in Zimbabwean infants","volume":"9","author":"Prendergast","year":"2014","journal-title":"PLoS One"},{"key":"2019112308003056400_fmz022-B40","doi-asserted-by":"crossref","first-page":"e30.","DOI":"10.1590\/s1678-9946201759030","article-title":"Immune development in HIV-exposed uninfected children born to HIV-infected women","volume":"59","author":"Miyamoto","year":"2017","journal-title":"Rev Inst Med Trop Sao Paulo"},{"key":"2019112308003056400_fmz022-B41","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1053\/gast.1996.v110.pm8566578","article-title":"Intestinal fatty acid-binding protein is a useful diagnostic marker for mesenteric infarction in humans","volume":"110","author":"Kanda","year":"1996","journal-title":"Gastroenterology"},{"key":"2019112308003056400_fmz022-B42","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.3109\/00365521.2011.627447","article-title":"Additional value of serum I-FABP levels for evaluating celiac disease activity in children","volume":"46","author":"Vreugdenhil","year":"2011","journal-title":"Scand J Gastroenterol"},{"key":"2019112308003056400_fmz022-B43","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1093\/infdis\/jiy271","article-title":"Intestinal integrity biomarkers in early antiretroviral-treated perinatally HIV-1-infected infants","volume":"218","author":"Koay","year":"2018","journal-title":"J Infect Dis"},{"key":"2019112308003056400_fmz022-B44","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1126\/science.1108661","article-title":"Accelerated intestinal epithelial cell turnover: a new mechanism of parasite expulsion","volume":"308","author":"Cliffe","year":"2005","journal-title":"Science"},{"key":"2019112308003056400_fmz022-B45","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1097\/QAI.0000000000000915","article-title":"Brief report: Differential associations of interleukin 6 and intestinal fatty acid-binding protein with progressive untreated HIV-1 infection in Rakai, Uganda","volume":"72","author":"Olwenyi","year":"2016","journal-title":"J Acquir Immune Defic Syndr"},{"key":"2019112308003056400_fmz022-B46","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1093\/cid\/ciy265","article-title":"Feeding-related gut microbial composition associates with peripheral T-cell activation and mucosal gene expression in African infants","volume":"67","author":"Wood","year":"2018","journal-title":"Clin Infect Dis"},{"key":"2019112308003056400_fmz022-B47","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1016\/j.micinf.2005.10.006","article-title":"The role of lipopolysaccharide-binding protein in modulating the innate immune response","volume":"8","author":"Zweigner","year":"2006","journal-title":"Microbes Infect"},{"key":"2019112308003056400_fmz022-B48","doi-asserted-by":"crossref","first-page":"257.","DOI":"10.3389\/fimmu.2016.00257","article-title":"Cytomegalovirus infection may contribute to the reduced immune function, growth, development, and health of HIV-exposed uninfected African children","volume":"7","author":"Filteau","year":"2016","journal-title":"Front Immunol"},{"key":"2019112308003056400_fmz022-B49","doi-asserted-by":"crossref","first-page":"328.","DOI":"10.3389\/fimmu.2018.00328","article-title":"The effect of human immunodeficiency virus and cytomegalovirus infection on infant responses to vaccines: a review","volume":"9","author":"Falconer","year":"2018","journal-title":"Front Immunol"},{"key":"2019112308003056400_fmz022-B50","doi-asserted-by":"crossref","first-page":"228.","DOI":"10.3389\/fmicb.2011.00228","article-title":"Gut microbiota of healthy and malnourished children in Bangladesh","volume":"2","author":"Monira","year":"2011","journal-title":"Front Microbiol"},{"key":"2019112308003056400_fmz022-B51","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1203\/01.PDR.0000076666.16021.5E","article-title":"Chronic T cell-mediated enteropathy in rural West African children: relationship with nutritional status and small bowel function","volume":"54","author":"Campbell","year":"2003","journal-title":"Pediatr Res"},{"key":"2019112308003056400_fmz022-B52","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1089\/aid.2016.0261","article-title":"Malnutrition in HIV-infected children is an indicator of severe disease with an impaired response to antiretroviral therapy","volume":"34","author":"Muenchhoff","year":"2018","journal-title":"AIDS Res Hum Retroviruses"},{"key":"2019112308003056400_fmz022-B53","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1097\/QAI.0000000000000096","article-title":"Immune activation is associated with increased gut microbial translocation in treatment-naive, HIV-infected children in a resource-limited setting","volume":"66","author":"Pilakka-Kanthikeel","year":"2014","journal-title":"J Acquir Immune Defic Syndr"},{"key":"2019112308003056400_fmz022-B54","doi-asserted-by":"crossref","first-page":"1589","DOI":"10.1089\/aid.2013.0097","article-title":"Short communication: evidence that microbial translocation occurs in HIV-infected children in the United Kingdom","volume":"29","author":"Fitzgerald","year":"2013","journal-title":"AIDS Res Hum Retroviruses"},{"key":"2019112308003056400_fmz022-B55","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1097\/INF.0000000000002082","article-title":"Infectious morbidity, mortality and nutrition in HIV-exposed, uninfected, formula fed infants: results from the HPTN 040\/PACTG 1043 Trial","volume":"37","author":"Yeganeh","year":"2018","journal-title":"Pediatr Infect Dis J 2018"},{"key":"2019112308003056400_fmz022-B56","year":"2018"},{"key":"2019112308003056400_fmz022-B57","first-page":"108","article-title":"Malnutrition decreases the odds of attaining motor milestones in HIV exposed children: results from a paediatric DREAM cohort","volume":"39","author":"Buonomo","year":"2015","journal-title":"Epidemiol Prev"}],"container-title":["Journal of Tropical Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/tropej\/article-pdf\/65\/6\/617\/31102001\/fmz022.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/tropej\/article-pdf\/65\/6\/617\/31102001\/fmz022.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,16]],"date-time":"2024-07-16T06:10:10Z","timestamp":1721110210000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/tropej\/article\/65\/6\/617\/5475883"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4,21]]},"references-count":57,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2019,4,21]]},"published-print":{"date-parts":[[2019,12,1]]}},"URL":"https:\/\/doi.org\/10.1093\/tropej\/fmz022","relation":{},"ISSN":["1465-3664"],"issn-type":[{"value":"1465-3664","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2019,12]]},"published":{"date-parts":[[2019,4,21]]}}}