{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T18:02:06Z","timestamp":1763748126748},"reference-count":41,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2020,4,17]],"date-time":"2020-04-17T00:00:00Z","timestamp":1587081600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Funda\u00e7\u00e3o de Amparo a Ci\u00eancia e Tecnologia do Estado de Pernambuco","award":["PBPG-1107-4.06\/18"],"award-info":[{"award-number":["PBPG-1107-4.06\/18"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>More than 95% of visceral leishmaniasis (VL) cases in Latin America occur in Brazil, most of them in the northeast. The objective of this study was to identify spatial clusters with the highest risks of VL and to analyse the temporal behaviour of the incidence and the effects of social vulnerability on the disease transmission dynamic in northeastern Brazil.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>All confirmed cases registered as residents in the state of Pernambuco during the period from 2007 to 2017 were analysed. The local empirical Bayesian method was applied and the association -between the VL incidence rate and municipal social vulnerability was tested via classic multivariate regression.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A total of 1186 new cases were registered during the study period. Spatial analysis showed heterogeneous distribution, with the highest rates observed in the S\u00e3o Francisco and Sert\u00e3o mesoregions. Moreover, the main factors associated with VL were urban infrastructure, income and work.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>It was observed that spatial and temporal techniques are important tools for defining risk areas for VL, in conjunction with the evaluation of indexes of social vulnerability, which was shown to be an important factor for comprehending associations with VL in the state of Pernambuco.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/trstmh\/traa024","type":"journal-article","created":{"date-parts":[[2020,3,14]],"date-time":"2020-03-14T06:25:53Z","timestamp":1584167153000},"page":"575-584","source":"Crossref","is-referenced-by-count":10,"title":["Analysis of spatial clustering, time trend, social vulnerability and risk of human visceral leishmaniasis in an endemic area in Brazil: an ecological study"],"prefix":"10.1093","volume":"114","author":[{"given":"Ac\u00e1cio W F","family":"Andrade","sequence":"first","affiliation":[{"name":"P\u00f3s-Gradua\u00e7\u00e3o em Ci\u00eancias da Sa\u00fade e Biol\u00f3gicas, Universidade Federal do Vale do S\u00e3o Francisco, Av. Jos\u00e9 de S\u00e1 Mani\u00e7oba, s\/n, Centro, Petrolina-PE, 56304-917, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos D F","family":"Souza","sequence":"additional","affiliation":[{"name":"Faculdade de Medicina, Universidade Federal de Alagoas Av. Manoel Severino Barbosa, Bom Sucesso, Arapiraca-AL, 57309-005, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodrigo F","family":"Carmo","sequence":"additional","affiliation":[{"name":"P\u00f3s-Gradua\u00e7\u00e3o em Ci\u00eancias da Sa\u00fade e Biol\u00f3gicas, Universidade Federal do Vale do S\u00e3o Francisco, Av. Jos\u00e9 de S\u00e1 Mani\u00e7oba, s\/n, Centro, Petrolina-PE, 56304-917, Brazil"},{"name":"P\u00f3s-Gradua\u00e7\u00e3o em Bioci\u00eancias, Universidade Federal do Vale do S\u00e3o Francisco Av. Jos\u00e9 de S\u00e1 Mani\u00e7oba, s\/n, Centro, Petrolina-PE, 56304-917, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2020,4,17]]},"reference":[{"key":"2020080507303417300_ref1","volume-title":"The control of the leishmaniasis: report of a meeting of the WHO Expert Committee on the Control of Leishmaniases","author":"World Health Organization","year":"2010"},{"key":"2020080507303417300_ref2","author":"World Health Organization"},{"key":"2020080507303417300_ref3","author":"Pan American Health Organization","journal-title":"68th session of the Regional Committee of WHO for the Americas"},{"issue":"5","key":"2020080507303417300_ref4","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0035671","article-title":"Leishmaniasis worldwide and global estimates of its incidence","volume":"7","author":"Alvar","year":"2012","journal-title":"PLoS 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