{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T11:49:30Z","timestamp":1740138570429,"version":"3.37.3"},"reference-count":24,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2020,8,24]],"date-time":"2020-08-24T00:00:00Z","timestamp":1598227200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100013986","name":"UK Government","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100013986","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,1,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>We assessed coverage of symptom screening and sputum testing for tuberculosis (TB) in hospital outpatient clinics in Ghana.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>In a cross-sectional study, we enrolled adults (\u226518 years) exiting the clinics reporting \u22651 TB symptom (cough, fever, night sweats or weight loss). Participants reporting a cough \u22652 weeks or a cough of any duration plus \u22652 other TB symptoms (per national criteria) and those self-reporting HIV-positive status were asked to give sputum for testing with Xpert MTB\/RIF.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>We enrolled 581 participants (median age 33 years [IQR: 24\u201348], 510\/581 [87.8%] female). The most common symptoms were fever (348, 59.9%), chest pain (282, 48.5%) and cough (270, 46.5%). 386\/581 participants (66.4%) reported symptoms to a healthcare worker, of which 157\/386 (40.7%) were eligible for a sputum test per national criteria. Only 31\/157 (19.7%) had a sputum test requested. Thirty-two additional participants gave sputum among 41 eligible based on positive HIV status. In multivariable analysis, symptom duration \u22652 weeks (adjusted odds ratio [aOR] 6.99, 95% confidence interval [CI] 2.08\u201323.51) and previous TB treatment (aOR: 6.25, 95% CI: 2.24\u201317.48) were the strongest predictors of having a sputum test requested. 6\/189 (3.2%) sputum samples had a positive Xpert MTB\/RIF result.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Opportunities for early identification of people with TB are being missed in health facilities in Ghana.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/trstmh\/traa080","type":"journal-article","created":{"date-parts":[[2020,8,5]],"date-time":"2020-08-05T19:32:16Z","timestamp":1596655936000},"page":"43-50","source":"Crossref","is-referenced-by-count":2,"title":["Missed opportunities for tuberculosis investigation in a municipal hospital in Ghana: evidence from patient exit interviews"],"prefix":"10.1093","volume":"115","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4257-4067","authenticated-orcid":false,"given":"Joyce B","family":"Der","sequence":"first","affiliation":[{"name":"TB Centre, London School of Hygiene & Tropical Medicine, London, UK"},{"name":"School of Public Health, University of Health and Allied Sciences, Hohoe, Ghana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel J","family":"Grint","sequence":"additional","affiliation":[{"name":"TB Centre, London School of Hygiene & Tropical Medicine, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clement T","family":"Narh","sequence":"additional","affiliation":[{"name":"School of Public Health, University of Health and Allied Sciences, Hohoe, Ghana"},{"name":"Institute for Medical Biostatistics, Epidemiology and Informatics, University Medical Centre of the Johannes Gutenberg University, Mainz, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank","family":"Bonsu","sequence":"additional","affiliation":[{"name":"National TB Control Program, Disease Control and Prevention Department, Ghana Health Service, Accra, Ghana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alison D","family":"Grant","sequence":"additional","affiliation":[{"name":"TB Centre, London School of Hygiene & Tropical Medicine, London, UK"},{"name":"Africa Health Research Institute, School of Laboratory Medicine & Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa"},{"name":"School of Public Health, University of the Witwatersrand, Johannesburg, South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2020,8,24]]},"reference":[{"volume-title":"Global tuberculosis report","year":"2019","author":"World Health 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