{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T07:13:13Z","timestamp":1790838793410,"version":"4.1.0"},"reference-count":36,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2020,9,10]],"date-time":"2020-09-10T00:00:00Z","timestamp":1599696000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Fondo Regional para el Desarrollo de la Ciencia y Tecnologia del Consejo Nacional de Ciencia y Tecnologia de Mexico","award":["FORDECYT 2009-01: 117535"],"award-info":[{"award-number":["FORDECYT 2009-01: 117535"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,1,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Many models for predicting dengue epidemics use incidence and short-term changes in climate variables, however, studies in real-life scenarios for correlations of seroprevalence (SP) with long-term climate variables and with integration of socio-economic factors are scarce. Our objective was to analyse the combined correlation between socio-economic and climate variables with the SP of dengue in Mexico.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We performed a seroepidemiological ecological study on the Mexican Pacific coast. Dengue SP was estimated by the presence of immunoglobulin G antibodies in 1278 inhabitants. We implemented multiple correlations with socio-economic, climatic and topographic characteristics using logistic regression, generalized linear models and non-linear regressions.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Dengue SP was 58%. The age-adjusted correlation was positive with the male sex, while a negative correlation was seen with socio-economic status (SES) and scholl level (SL). The annual temperature showed a positive correlation, while the altitude was negative. It should be noted that these correlations showed a marked \u2018S\u2019 shape in the non-linear model, suggesting three clearly defined scenarios for dengue risk.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Low SES and SL showed an unexpected paradoxical protective effect. Altitude above sea level and annual temperature are the main determinants for dengue in the long term. The identification of three clearly delineated scenarios for transmission could improve the accuracy of predictive models.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/trstmh\/traa083","type":"journal-article","created":{"date-parts":[[2020,8,17]],"date-time":"2020-08-17T12:53:17Z","timestamp":1597668797000},"page":"63-73","source":"Crossref","is-referenced-by-count":3,"title":["Demographic and climatic factors associated with dengue prevalence in a hyperendemic zone in Mexico: an empirical approach"],"prefix":"10.1093","volume":"115","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1111-6845","authenticated-orcid":false,"given":"Francisco","family":"Espinoza-Gomez","sequence":"first","affiliation":[{"name":"Facultad de Medicina, Universidad de Colima, Avenida Universidad 333, Colonia Las Viboras, Colima, Colima, Mexico 28040"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oscar Alberto","family":"Newton-Sanchez","sequence":"additional","affiliation":[{"name":"Facultad de Medicina, Universidad de Colima, Avenida Universidad 333, Colonia Las Viboras, Colima, Colima, Mexico 28040"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3061-521X","authenticated-orcid":false,"given":"Arnulfo Hernan","family":"Nava-Zavala","sequence":"additional","affiliation":[{"name":"Facultad\u00a0de Medicina Universidad Autonoma de Guadalajara"},{"name":"Unidad de Investigaci\u00f3n Biom\u00e9dica, Centro M\u00e9dico Nacional de Occidente, Instituto Mexicano del Seguro Social, Guadalajara, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria G","family":"Zavala-Cerna","sequence":"additional","affiliation":[{"name":"Facultad\u00a0de Medicina Universidad Autonoma de Guadalajara"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabian","family":"Rojas-Larios","sequence":"additional","affiliation":[{"name":"Facultad de Medicina, Universidad de Colima, Avenida Universidad 333, Colonia Las Viboras, Colima, Colima, Mexico 28040"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivan","family":"Delgado-Enciso","sequence":"additional","affiliation":[{"name":"Facultad de Medicina, Universidad de Colima, Avenida Universidad 333, Colonia Las Viboras, Colima, Colima, Mexico 28040"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abril B","family":"Martinez-Rizo","sequence":"additional","affiliation":[{"name":"Facultad de Medicina y Ciencias Quimicas de la Universidad Autonoma de Nayarit"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felipe","family":"Lozano-Kasten","sequence":"additional","affiliation":[{"name":"Facultad de Medicina de la Universidad de Guadalajara"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,9,10]]},"reference":[{"key":"2021010701303905600_bib1","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1146\/annurev-ento-011019-024918","article-title":"The global expansion of dengue: how Aedes aegypti mosquitoes enabled the first pandemic arbovirus","volume":"65","author":"Brady","year":"2019","journal-title":"Annu Rev Entomol."},{"key":"2021010701303905600_bib2","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.actatropica.2018.01.005","article-title":"Low socioeconomic condition and the risk of dengue fever: a direct relationship","volume":"180","author":"Farinelli","year":"2018","journal-title":"Acta Trop."},{"issue":"4","key":"2021010701303905600_bib3","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1016\/j.jiph.2019.08.015","article-title":"Risk factors for dengue outbreaks in Odisha, India: a case-control study","volume":"13","author":"Swain","year":"2020","journal-title":"J Infect Public Health."},{"issue":"9","key":"2021010701303905600_bib4","first-page":"1153","article-title":"Dificultad para el diagn\u00f3stico cl\u00ednico temprano del dengue en un \u00e1rea end\u00e9mica y su impacto sobre el manejo m\u00e9dico inicial","volume":"134","author":"Mart\u00ednez-Vega","year":"2006","journal-title":"Rev Med Chile."},{"key":"2021010701303905600_bib5","doi-asserted-by":"crossref","first-page":"140004","DOI":"10.1038\/sdata.2014.4","article-title":"A global compendium of human dengue virus occurrence","volume":"1","author":"Messina","year":"2014","journal-title":"Sci Data."},{"issue":"1","key":"2021010701303905600_bib6","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1179\/2047773214Y.0000000168","article-title":"Is dengue a disease of poverty? 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