{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,8]],"date-time":"2025-09-08T06:49:10Z","timestamp":1757314150076,"version":"3.37.3"},"reference-count":5,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2020,11,25]],"date-time":"2020-11-25T00:00:00Z","timestamp":1606262400000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"UK Medical Research Council","doi-asserted-by":"crossref","award":["MR\/K007211\/1"],"award-info":[{"award-number":["MR\/K007211\/1"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"crossref"}]},{"name":"UK AID","award":["WT099946MA"],"award-info":[{"award-number":["WT099946MA"]}]},{"DOI":"10.13039\/501100000780","name":"European Union","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,12,16]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>While morbidity attributable to podoconiosis is relatively well studied, its pattern of mortality has not been established.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We compared the age-standardised mortality ratios (SMRs) of two datasets from northern Ethiopia: podoconiosis patients enrolled in a 1-y trial and a Health and Demographic Surveillance System cohort.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The annual crude mortality rate per 1000 population for podoconiosis patients was 28.7 (95% confidence interval [CI] 17.3 to 44.8; n=663) while that of the general population was 2.8 (95% CI 2.3 to 3.4; n=44\u00a0095). The overall SMR for the study period was 6.0 (95% CI 3.6 to 9.4).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Podoconiosis patients experience elevated mortality compared with the general population and further research is required to understand the reasons.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/trstmh\/traa150","type":"journal-article","created":{"date-parts":[[2020,11,11]],"date-time":"2020-11-11T01:57:08Z","timestamp":1605059828000},"page":"1035-1037","source":"Crossref","is-referenced-by-count":5,"title":["Excess mortality among people with podoconiosis: secondary analysis of two Ethiopian cohorts"],"prefix":"10.1093","volume":"114","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9101-849X","authenticated-orcid":false,"given":"Hannah","family":"Masraf","sequence":"first","affiliation":[{"name":"Centre for Global Health Research, Brighton and Sussex Medical School, University of Sussex, Falmer, Brighton BN1\u00a09PX, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Temesgen","family":"Azemeraw","sequence":"additional","affiliation":[{"name":"Dabat Research Centre, University of Gondar, Gondar, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meseret","family":"Molla","sequence":"additional","affiliation":[{"name":"School of Public Health, Addis Ababa University, PO Box 9086, Addis Ababa, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher Iain","family":"Jones","sequence":"additional","affiliation":[{"name":"Department of Primary Care and Public Health, Brighton and Sussex Medical School, University of Sussex, Brighton BN1 9PX, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen","family":"Bremner","sequence":"additional","affiliation":[{"name":"Department of Primary Care and Public Health, Brighton and Sussex Medical School, University of Sussex, Brighton BN1 9PX, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moses","family":"Ngari","sequence":"additional","affiliation":[{"name":"KEMRI\/Wellcome Trust Research Programme, Kilifi, Kenya"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James A","family":"Berkley","sequence":"additional","affiliation":[{"name":"KEMRI\/Wellcome Trust Research Programme, Kilifi, Kenya"},{"name":"Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esther","family":"Kivaya","sequence":"additional","affiliation":[{"name":"KEMRI\/Wellcome Trust Research Programme, Kilifi, Kenya"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Greg","family":"Fegan","sequence":"additional","affiliation":[{"name":"KEMRI\/Wellcome Trust Research Programme, Kilifi, Kenya"},{"name":"Swansea University Medical School, Swansea, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abreham","family":"Tamiru","sequence":"additional","affiliation":[{"name":"International Orthodox Christian Charities Podoconiosis Project, Debre Markos, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abebe","family":"Kelemework","sequence":"additional","affiliation":[{"name":"International Orthodox Christian Charities Podoconiosis Project, Debre Markos, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Trudie","family":"Lang","sequence":"additional","affiliation":[{"name":"KEMRI\/Wellcome Trust Research Programme, Kilifi, Kenya"},{"name":"Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melanie J","family":"Newport","sequence":"additional","affiliation":[{"name":"Centre for Global Health Research, Brighton and Sussex Medical School, University of Sussex, Falmer, Brighton BN1\u00a09PX, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2796-7468","authenticated-orcid":false,"given":"Gail","family":"Davey","sequence":"additional","affiliation":[{"name":"Centre for Global Health Research, Brighton and Sussex Medical School, University of Sussex, Falmer, Brighton BN1\u00a09PX, UK"},{"name":"School of Public Health, Addis Ababa University, PO Box 9086, Addis Ababa, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2020,11,24]]},"reference":[{"issue":"7","key":"2020121600040355000_bib1","doi-asserted-by":"crossref","first-page":"e2865","DOI":"10.1371\/journal.pntd.0002865","article-title":"The Global Burden of Disease Study 2010: interpretation and implications for the neglected tropical diseases","volume":"8","author":"Hotez","year":"2014","journal-title":"PLoS Negl Trop Dis"},{"key":"2020121600040355000_bib2","volume-title":"Podoconiosis: endemic non-filarial elephantiasis","author":"Deribe","year":"2016","edition":"1st ed"},{"issue":"9","key":"2020121600040355000_bib3","doi-asserted-by":"crossref","first-page":"e012308","DOI":"10.1136\/bmjopen-2016-012308","article-title":"Burden assessment of podoconiosis in Wayu Tuka woreda, east Wollega zone, western Ethiopia: a community-based cross-sectional study","volume":"6","author":"Bekele","year":"2016","journal-title":"BMJ Open"},{"issue":"7","key":"2020121600040355000_bib4","doi-asserted-by":"crossref","first-page":"e795","DOI":"10.1016\/S2214-109X(18)30124-4","article-title":"Lymphoedema management to prevent acute dermatolymphangioadenitis in podoconiosis in northern Ethiopia (GoLBeT): a pragmatic randomised controlled trial","volume":"6","author":"Negussie","year":"2018","journal-title":"Lancet Glob Health"},{"author":"INDEPTH Network. 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