{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T14:48:34Z","timestamp":1791384514134,"version":"4.3.3"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2020,12,21]],"date-time":"2020-12-21T00:00:00Z","timestamp":1608508800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Central Laboratory of Public Health"},{"DOI":"10.13039\/501100003593","name":"National Council for Scientific and Technological Development","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,8,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Despite high seroprevalence of asymptomatic infection in humans, toxoplasmosis can manifest as a severe systemic disease, as occurs in the congenital infection. Here we evaluate the seroprevalence of Toxoplasma infection among pregnant women in a highly urbanized area of Brazil.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A robust seroepidemiological study was conducted using laboratory databases of anti-Toxoplasma gondii serological results together with information on age, month\/year of diagnosis and place of residence of pregnant women in the public health system of the city of Juiz de Fora, Brazil.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Of 5895 pregnant women analysed, 54.7% showed seronegativity and 44.4% showed seropositivity for immunoglobulin G (IgG) antibodies against Toxoplasma gondii. This seropositivity rate increased to 68.3% when only considering participants from rural areas. Multivariate analysis revealed higher odds of being seropositive associated with age (odds ratio [OR] 1.06 [confidence interval {CI} 1.05 to 1.07]) and with living in rural areas (OR 2.96 [CI 1.64 to 5.36]). The spatial distribution of IgG seropositivity indicated a higher prevalence concentrated in rural and peripheral neighbourhoods.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>This is the first report to use spatial analysis to show a cluster of Toxoplasma infection in rural and peripheral neighbourhoods of a highly urbanized municipality, which highlights the need for adequate healthcare actions to be implemented for women living in these areas.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/trstmh\/traa153","type":"journal-article","created":{"date-parts":[[2020,11,19]],"date-time":"2020-11-19T05:03:17Z","timestamp":1605762197000},"page":"896-903","source":"Crossref","is-referenced-by-count":15,"title":["Rural residence remains a risk factor for <i>Toxoplasma<\/i> infection among pregnant women in a highly urbanized Brazilian area: a robust cross-sectional study"],"prefix":"10.1093","volume":"115","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5183-1141","authenticated-orcid":false,"given":"Luciana Maria Ribeiro","family":"Antinarelli","sequence":"first","affiliation":[{"name":"Faculdade de Medicina, Programa de P\u00f3s-Gradua\u00e7\u00e3o em Ci\u00eancias da Sa\u00fade: Infectologia e Medicina Tropical, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais 30130-100, Brazil"},{"name":"Laborat\u00f3rio Central da Prefeitura de Juiz de Fora, Juiz de Fora, Minas Gerais 36020-485, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e1rcio Roberto","family":"Silva","sequence":"additional","affiliation":[{"name":"Embrapa Gado de Leite, Juiz de Fora, Minas Gerais 36038-330, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo Jos\u00e9 de Paula Sousa e","family":"Guimar\u00e3es","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Geoprocessamento, Instituto Evandro Chagas, Ananindeua, Par\u00e1 67030-000, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana Sequetto","family":"Terror","sequence":"additional","affiliation":[{"name":"Departamento de Parasitologia, Microbiologia e Imunologia, Universidade Federal de Juiz de Fora, Juiz de Fora, Minas Gerais 36036-900, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patr\u00edcia Enham","family":"Lima","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio Central da Prefeitura de Juiz de Fora, Juiz de Fora, Minas Gerais 36020-485, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joelma de Souza Coimbra","family":"Ishii","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio Central da Prefeitura de Juiz de Fora, Juiz de Fora, Minas Gerais 36020-485, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patr\u00edcia Fabiano","family":"Muniz","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio Central da Prefeitura de Juiz de Fora, Juiz de Fora, Minas Gerais 36020-485, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elaine Soares","family":"Coimbra","sequence":"additional","affiliation":[{"name":"Departamento de Parasitologia, Microbiologia e Imunologia, Universidade Federal de Juiz de Fora, Juiz de Fora, Minas Gerais 36036-900, 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