{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T13:55:20Z","timestamp":1791381320823,"version":"4.3.3"},"reference-count":44,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Belgian Directorate General for Development Cooperation and Humanitarian Aid"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,5,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Zoonoses pose major threats to the health of humans, domestic animals and wildlife, as seen in the COVID-19 pandemic. Zoonoses are the commonest source of emerging human infections and inter-species transmission is facilitated by anthropogenic factors such as encroachment and destruction of wilderness areas, wildlife trafficking and climate change. South Africa was selected for a \u2018One Health\u2019 study to identify research priorities for control of zoonoses due to its complex disease burden and an overstretched health system.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A multidisciplinary group of 18 experts identified priority zoonotic diseases, knowledge gaps and proposed research priorities for the next 5 y. Each priority was scored using predefined criteria by another group of five experts and then weighted by a reference group (n=28) and the 18 experts.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Seventeen diseases were mentioned with the top five being rabies (14\/18), TB (13\/18), brucellosis (11\/18), Rift Valley fever (9\/11) and cysticercosis (6\/18). In total, 97 specific research priorities were listed, with the majority on basic epidemiological research (n=57), such as measuring the burden of various zoonoses (n=24), followed by 20 on development of new interventions. The highest research priority score was for improving existing interventions (0.77\/1.0), followed by health policy and systems research (0.72\/1.0).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Future zoonotic research should improve understanding of zoonotic burden and risk factors and new interventions in public health. People with limited rural services, immunocompromised, in informal settlements and high-risk occupations, should be the highest research priority.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/trstmh\/trab039","type":"journal-article","created":{"date-parts":[[2021,2,19]],"date-time":"2021-02-19T13:51:29Z","timestamp":1613742689000},"page":"538-550","source":"Crossref","is-referenced-by-count":12,"title":["Research priorities for control of zoonoses in South Africa"],"prefix":"10.1093","volume":"115","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8089-7193","authenticated-orcid":false,"given":"Greg","family":"Simpson","sequence":"first","affiliation":[{"name":"Department of Production Animal Studies, Faculty of Veterinary Sciences, University of Pretoria, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabiola","family":"Quesada","sequence":"additional","affiliation":[{"name":"Wildlife Conservation Medicine Foundation, South 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