{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T10:24:06Z","timestamp":1792664646783,"version":"4.5.0"},"reference-count":43,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2021,3,25]],"date-time":"2021-03-25T00:00:00Z","timestamp":1616630400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100010794","name":"Faculty of Medicine","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010794","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,1,20]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Scabies is a neglected tropical disease (NTD) of the skin that is caused by the mite Sarcoptes scabiei. It is considered to be an important public health problem in many regions. The disease is at its most prevalent in low-resource countries where there are overcrowded living conditions coupled with poor hygiene. In some regions, mass drug administration using ivermectin is a key population-based approach to the control of scabies. Before starting a patient on specific treatment, confirming the diagnosis by accurate and rapid identification of the organism is critical. Different laboratory-based techniques for scabies have been developed in the last few decades. These include direct microscopy and histopathology. More recently, serological testing, dermoscopy and different molecular techniques have been developed as diagnostic methods for scabies. To date, none of these, apart from microscopy and dermoscopy, has been translated into routine clinical laboratory practice. A simple point-of-care or laboratory test would provide a rapid and confirmed diagnosis and early institution of effective treatment. In this review we present an update on the laboratory techniques currently in use for the identification of scabies.<\/jats:p>","DOI":"10.1093\/trstmh\/trab049","type":"journal-article","created":{"date-parts":[[2021,3,4]],"date-time":"2021-03-04T20:12:51Z","timestamp":1614888771000},"page":"4-9","source":"Crossref","is-referenced-by-count":20,"title":["Laboratory-based diagnosis of scabies: a review of the current status"],"prefix":"10.1093","volume":"116","author":[{"given":"Emmanuel Edwar","family":"Siddig","sequence":"first","affiliation":[{"name":"Nile University, Faculty of Medicine, Khartoum, Sudan"},{"name":"Erasmus Medical Center, University Medical Center Rotterdam, Department of Medical Microbiology and Infectious Diseases, Wytemaweg 80\u00a03015 CN, Rotterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5835-1167","authenticated-orcid":false,"given":"Roderick","family":"Hay","sequence":"additional","affiliation":[{"name":"Kings College London, Guys Campus, London SE1\u00a09RT, \u00a0UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,3,25]]},"reference":[{"issue":"3","key":"2022031008052427100_bib1","doi-asserted-by":"crossref","first-page":"e0007182","DOI":"10.1371\/journal.pntd.0007182","article-title":"A systematic review of scabies transmission models and data to evaluate the cost-effectiveness of scabies interventions","volume":"13","author":"van der Linden","year":"2019","journal-title":"PLoS Negl Trop Dis"},{"key":"2022031008052427100_bib2","volume-title":"Scabies 2021","author":"World Health Organization"},{"key":"2022031008052427100_bib3","author":"National Institute of Clinical Excellence (NICE). 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