{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T10:30:17Z","timestamp":1776853817542,"version":"3.51.2"},"reference-count":41,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2021,10,18]],"date-time":"2021-10-18T00:00:00Z","timestamp":1634515200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/501100006162","name":"FACEPE","doi-asserted-by":"publisher","award":["PBPG-1107-4.06\/18"],"award-info":[{"award-number":["PBPG-1107-4.06\/18"]}],"id":[{"id":"10.13039\/501100006162","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,5,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Visceral leishmaniasis is a neglected tropical disease of great importance to public health due to its wide distribution and close relationship with social and economic conditions. This study aimed to analyse the spatiotemporal dynamics of human visceral leishmaniasis (HVL) in an endemic state in the Northeast Region of Brazil and its spatial correlation with the Social Vulnerability Index (SVI) and the Municipal Human Development Index (MHDI).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>The study included all confirmed cases of HVL in Bahia from 2010 to 2017. A joinpoint regression model was used for trend analysis. Incidence rates were smoothed by a local empirical Bayesian model. Global and local Moran indices and space\u2013time scan statistics were used for identification of spatial clusters. Bivariate and multivariate analyses were carried out to investigate the relationship between HVL incidence and the SVI and MHDI.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Cases of HVL demonstrated stationary behaviour during the period analysed. A significant association was observed between the HVL incidence rate and social vulnerability, with high-risk clusters concentrated in the central region of the state.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>HVL has a strong correlation with social vulnerability in the state of Bahia. This study may provide assistance in planning actions and organizing health services to combat HVL.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/trstmh\/trab160","type":"journal-article","created":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T21:38:35Z","timestamp":1633124315000},"page":"469-478","source":"Crossref","is-referenced-by-count":7,"title":["Temporal and spatial trends in human visceral leishmaniasis in an endemic area in Northeast Brazil and their association with social vulnerability"],"prefix":"10.1093","volume":"116","author":[{"given":"Ac\u00e1cio W F","family":"Andrade","sequence":"first","affiliation":[{"name":"P\u00f3s-Gradua\u00e7\u00e3o em Ci\u00eancias da Sa\u00fade e Biol\u00f3gicas, Universidade Federal do Vale do S\u00e3o Francisco, Av. Jos\u00e9 de S\u00e1 Mani\u00e7oba, sn, Centro, Petrolina, Pernambuco 56304-917, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7995-1893","authenticated-orcid":false,"given":"Carlos D F","family":"Souza","sequence":"additional","affiliation":[{"name":"Faculdade de Medicina, Universidade Federal de Alagoas, Av. Manoel Severino Barbosa, Bom Sucesso, Arapiraca, Alagoas 57309-005, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9601-6995","authenticated-orcid":false,"given":"Rodrigo F","family":"Carmo","sequence":"additional","affiliation":[{"name":"P\u00f3s-Gradua\u00e7\u00e3o em Ci\u00eancias da Sa\u00fade e Biol\u00f3gicas, Universidade Federal do Vale do S\u00e3o Francisco, Av. 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