{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T11:49:57Z","timestamp":1740138597462,"version":"3.37.3"},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2022,6,24]],"date-time":"2022-06-24T00:00:00Z","timestamp":1656028800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/501100004901","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de Minas Gerais","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004901","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,12,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Sarcopenia is a common complication of cirrhosis and an important predictor of morbimortality. We aimed to determine the prevalence of sarcopenia and its associated factors in hepatosplenic schistosomiasis (HSS) as well as to evaluate whether muscle mass and function are associated with variceal upper gastrointestinal bleeding (VUGIB) and previous splenectomy in subjects without other liver diseases.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We conducted a cross-sectional study including adults with HSS who underwent clinical, biochemical, anthropometric, muscle strength and physical performance evaluations and were submitted to bioelectrical impedance analysis and abdominal ultrasound. Sarcopenia was diagnosed according to the 2019 European consensus criteria.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A total of 66 patients with HSS (62.1% male; mean age 48.8\u00b18.6\u00a0y) were included. Overall, six subjects (9.1%) were diagnosed with probable sarcopenia and none had confirmed sarcopenia. Fat-free body mass index (BMI) was independently associated with VUGIB (odds ratio 0.701 [95% confidence interval 0.51 to 0.96]; p=0.025). Compared with patients who did not undergo surgery, individuals who underwent esophagogastric devascularization combined with splenectomy (EGDS) had higher serum lipid levels, fat percentage and frequency of metabolic syndrome, with lower skeletal muscle mass index and hand grip strength.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>HSS mansoni seems not to cause sarcopenia. However, a lower fat-free BMI was associated with previous VUGIB and the subgroup of patients who underwent EGDS presented higher lipid levels, fat percentage and frequency of metabolic syndrome and lower muscle mass and function.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/trstmh\/trac052","type":"journal-article","created":{"date-parts":[[2022,6,24]],"date-time":"2022-06-24T11:30:00Z","timestamp":1656070200000},"page":"1145-1153","source":"Crossref","is-referenced-by-count":3,"title":["Sarcopenia, body composition and factors associated with variceal gastrointestinal bleeding and splenectomy in hepatosplenic schistosomiasis mansoni"],"prefix":"10.1093","volume":"116","author":[{"given":"Fernanda A","family":"Barbosa","sequence":"first","affiliation":[{"name":"Faculdade de Medicina da Universidade Federal de Minas Gerais , Avenida Professor Alfredo Balena, 190 - Santa Efig\u00eania, Belo Horizonte, Minas Gerais, 30130-100, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7199-9980","authenticated-orcid":false,"given":"Mateus J","family":"Nardelli","sequence":"additional","affiliation":[{"name":"Faculdade de Medicina da Universidade Federal de Minas Gerais , Avenida Professor Alfredo Balena, 190 - Santa Efig\u00eania, Belo Horizonte, Minas Gerais, 30130-100, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guilherme G L","family":"Can\u00e7ado","sequence":"additional","affiliation":[{"name":"Faculdade de Medicina da Universidade Federal de Minas Gerais , Avenida Professor Alfredo Balena, 190 - Santa Efig\u00eania, Belo Horizonte, Minas Gerais, 30130-100, Brazil"},{"name":"Instituto Alfa de Gastroenterologia, Hospital das Cl\u00ednicas da Universidade Federal de Minas Gerais , Avenida Professor Alfredo Balena, 110 - Santa Efig\u00eania, Belo Horizonte, Minas Gerais, 30130-100, Brazil"},{"name":"Hospital da Pol\u00edcia Militar de Minas Gerais , Rua Pac\u00edfico Mascarenhas, s\/n-Santa Efig\u00eania, Belo Horizonte, Minas Gerais, 30110-013, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine F","family":"Silva","sequence":"additional","affiliation":[{"name":"Faculdade de Medicina da Universidade Federal de Minas Gerais , Avenida Professor Alfredo Balena, 190 - Santa Efig\u00eania, Belo Horizonte, Minas Gerais, 30130-100, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernanda M F","family":"Os\u00f3rio","sequence":"additional","affiliation":[{"name":"Instituto Alfa de Gastroenterologia, Hospital das Cl\u00ednicas da Universidade Federal de Minas Gerais , Avenida Professor Alfredo Balena, 110 - Santa Efig\u00eania, Belo Horizonte, Minas Gerais, 30130-100, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodolfo F Q","family":"Melo","sequence":"additional","affiliation":[{"name":"Faculdade de Medicina da Universidade Federal de Minas Gerais , Avenida Professor Alfredo Balena, 190 - Santa Efig\u00eania, Belo Horizonte, Minas Gerais, 30130-100, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela O L","family":"Taranto","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Diagn\u00f3stico por Imagem, Hospital das Cl\u00ednicas da Universidade Federal de Minas Gerais , Avenida Professor Alfredo Balena 110 - Santa Efig\u00eania, Belo Horizonte, Minas Gerais, 30130-100, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teresa C A","family":"Ferrari","sequence":"additional","affiliation":[{"name":"Faculdade de Medicina da Universidade Federal de Minas Gerais , Avenida Professor Alfredo Balena, 190 - Santa Efig\u00eania, Belo Horizonte, Minas Gerais, 30130-100, Brazil"},{"name":"Instituto Alfa de Gastroenterologia, Hospital das Cl\u00ednicas da Universidade Federal de Minas Gerais , Avenida Professor Alfredo Balena, 110 - Santa Efig\u00eania, Belo Horizonte, Minas Gerais, 30130-100, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia A","family":"Couto","sequence":"additional","affiliation":[{"name":"Faculdade de Medicina da Universidade Federal de Minas Gerais , Avenida Professor Alfredo Balena, 190 - Santa Efig\u00eania, Belo Horizonte, Minas Gerais, 30130-100, Brazil"},{"name":"Instituto Alfa de Gastroenterologia, Hospital das Cl\u00ednicas da Universidade Federal de Minas Gerais , Avenida Professor Alfredo Balena, 110 - 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