{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T06:42:59Z","timestamp":1790923379739,"version":"4.1.0"},"reference-count":57,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2022,8,5]],"date-time":"2022-08-05T00:00:00Z","timestamp":1659657600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Widespread respiratory infections with high morbidity rates caused by respiratory viruses represent a significant global public health problem. Our objective was to describe cases and deaths from severe acute respiratory infection (SARI) in Brazil over the past 8\u00a0y as well as changes in the distribution and risk of illness and death from SARI before and in the first year of the coronavirus disease 2019 (COVID-19) pandemic (FYP).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed a descriptive epidemiological study of hospitalized SARI cases and deaths between 2013 and 2020 in Brazil, separated into pre-pandemic (2013 to 2019) and FYP (2020). We estimate the increase in SARI cases and deaths in the FYP as well as the mortality and infection risks attributable to the FYP (MRAP and IRAP, respectively).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In 2020, an excess of 425\u00a0054 cases and 109\u00a0682 deaths was observed, with a significant increase in the risk of falling ill and dying from SARI, with an IRAP of 200.06 and an MRAP of 51.68 cases per 100\u00a0000 inhabitants. The increase in SARI cases and deaths was particularly prominent among patients with COVID-19, the elderly, males, those self-identifying as mixed race and patients with heart disease and diabetes. We conclude that an important increase in morbidity and mortality due to SARI was observed in the FYP. More vulnerable groups and those living in the Southeast, North and Center-West regions of the country suffered the most.<\/jats:p><\/jats:sec>","DOI":"10.1093\/trstmh\/trac074","type":"journal-article","created":{"date-parts":[[2022,8,5]],"date-time":"2022-08-05T13:50:05Z","timestamp":1659707405000},"page":"161-173","source":"Crossref","is-referenced-by-count":13,"title":["Clinical and epidemiological aspects of severe acute respiratory infection: before and during the first year of the COVID-19 pandemic in Brazil"],"prefix":"10.1093","volume":"117","author":[{"given":"Felipe Cotrim","family":"de Carvalho","sequence":"first","affiliation":[{"name":"Center of Tropical Medicine, Faculty of Medicine, University of Brasilia , Brasilia , Brazil"},{"name":"Surveillance Secretariat in Health, Ministry of Health , Bras\u00edlia, Federal District , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erica Tatiane","family":"da Silva","sequence":"additional","affiliation":[{"name":"Evidence Program for Health Policies and Technologies, Oswaldo Cruz Foundation , Brasilia, Federal District , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walquiria Aparecida Ferreira","family":"de Almeida","sequence":"additional","affiliation":[{"name":"Surveillance Secretariat in Health, Ministry of Health , Bras\u00edlia, Federal District , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matheus Almeida","family":"Maroneze","sequence":"additional","affiliation":[{"name":"Surveillance Secretariat in Health, Ministry of Health , Bras\u00edlia, Federal District , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaqueline de Araujo","family":"Schwartz","sequence":"additional","affiliation":[{"name":"Surveillance Secretariat in Health, Ministry of Health , Bras\u00edlia, Federal District , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o Pedro Vieira","family":"Jardim","sequence":"additional","affiliation":[{"name":"Center of Tropical Medicine, Faculty of Medicine, University of Brasilia , Brasilia , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry Maia","family":"Peixoto","sequence":"additional","affiliation":[{"name":"Center of Tropical Medicine, Faculty of Medicine, University of Brasilia , Brasilia , Brazil"},{"name":"National Institute of Science and Technology for Health Technology Assessment , Porto Alegre , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,8,5]]},"reference":[{"issue":"1","key":"2023030119483833300_","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S1473-3099(01)00170-0","article-title":"Estimates of world-wide distribution of child deaths from acute respiratory infections","volume":"2","author":"Williams","year":"2002","journal-title":"Lancet Infect Dis"},{"issue":"11","key":"2023030119483833300_","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1016\/S1473-3099(18)30310-4","article-title":"Estimates of the global, regional, and national morbidity, mortality, and aetiologies of lower respiratory infections in 195 countries, 1990\u20132016: a systematic analysis for the Global Burden of Disease Study 2016","volume":"18","author":"Troeger","year":"2018","journal-title":"Lancet Infect Dis"},{"issue":"10100","key":"2023030119483833300_","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1016\/S0140-6736(17)32152-9","article-title":"Global, regional, and national age-sex specific mortality for 264 causes of death, 1980-2016: a systematic analysis for the Global Burden of Disease Study 2016","volume":"390","author":"Naghavi","year":"2017","journal-title":"Lancet"},{"key":"2023030119483833300_","article-title":"Weekly epidemiological update on COVID-19 - 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