{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T20:30:12Z","timestamp":1790627412820,"version":"4.1.0"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2022,12,13]],"date-time":"2022-12-13T00:00:00Z","timestamp":1670889600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"National Research Council of Brazil","award":["410595\/2006\u20133"],"award-info":[{"award-number":["410595\/2006\u20133"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,5,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>The Brazilian Ministry of Health (MoH) recommends double screening (DS) for syphilis and HIV during the first and third trimesters of antenatal care (ANC) to mitigate vertical transmission. We surveyed DS outcomes and their associated factors in a priority Brazilian municipality with &amp;gt;100 000 inhabitants who face challenges for both health problems.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A total of 399 women were followed up throughout pregnancy using medical records. Spatial and multinomial logistic analyses were performed.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>There was an incidence rate of 24.8%, 59.4% and 15.8% for \u2018full DS\u2019, \u2018partial DS\u2019 and \u2018without DS\u2019, respectively. Younger women and those with a history of both prematurity and multiparity were less likely to be in the \u2018full DS\u2019 category. There was an overlap of high-density clusters of \u2018full DS\u2019 and \u2018ANC in better quality basic health units\u2019, adherent to both the Family Health Strategy and the National Program for Access and Quality Improvement in Primary Care.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>The poor DS outcomes presented in 75% of the cases were mostly linked to delays in starting ANC appointments or their discontinuity. Thus, the MoH recommendations, accompanied by ongoing training, technical assistance and the periodic evaluation of their implementation, need to effectively reach providers and promote counseling and awareness about the importance of DS for pregnant women.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/trstmh\/trac113","type":"journal-article","created":{"date-parts":[[2022,12,13]],"date-time":"2022-12-13T09:13:13Z","timestamp":1670922793000},"page":"336-348","source":"Crossref","is-referenced-by-count":2,"title":["Double screening for syphilis and HIV in pregnant women in a priority municipality for the elimination of vertical transmission in Brazil: incidence, risk factors and spatial analysis"],"prefix":"10.1093","volume":"117","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3179-0781","authenticated-orcid":false,"given":"Lidiane Martins Gon\u00e7alves","family":"Fava","sequence":"first","affiliation":[{"name":"Federal University of Juiz de Fora , Juiz de Fora, Minas Gerais 36.036-900 , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana L\u00facia de Lima","family":"Guedes","sequence":"additional","affiliation":[{"name":"Federal University of Juiz de Fora , Juiz de Fora, Minas Gerais 36.036-900 , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luiz Cl\u00e1udio","family":"Ribeiro","sequence":"additional","affiliation":[{"name":"Federal University of Juiz de Fora , Juiz de Fora, Minas Gerais 36.036-900 , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen Perches Gomide","family":"Pinto","sequence":"additional","affiliation":[{"name":"Federal University of Juiz de Fora , Juiz de Fora, Minas Gerais 36.036-900 , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo Jos\u00e9 de Paula","family":"Souza e Guimar\u00e3es","sequence":"additional","affiliation":[{"name":"Evandro Chagas Institute , Ananindeua, Par\u00e1 67.030-000 , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e1rio C\u00edrio","family":"Nogueira","sequence":"additional","affiliation":[{"name":"Federal University of Juiz de Fora , Juiz de Fora, Minas Gerais 36.036-900 , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e1rcio Jos\u00e9 Martins","family":"Alves","sequence":"additional","affiliation":[{"name":"Federal University of Juiz de Fora , Juiz de Fora, Minas Gerais 36.036-900 , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e1rcio Roberto","family":"Silva","sequence":"additional","affiliation":[{"name":"Federal University of Juiz de Fora , Juiz de Fora, Minas Gerais 36.036-900 , Brazil"},{"name":"Embrapa Dairy Cattle , Juiz de Fora, Minas Gerais 36.038-330 , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,12,13]]},"reference":[{"issue":"9","key":"2023050217525178300_bib1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1590\/0102-311X00118215","article-title":"Avalia\u00e7\u00e3o da cascata de cuidado na preven\u00e7\u00e3o da transmiss\u00e3o vertical do HIV no Brasil","volume":"32","author":"Miranda","year":"2016","journal-title":"Cad Sa\u00fade P\u00fablica"},{"issue":"7","key":"2023050217525178300_bib2","first-page":"CD003510","article-title":"Antiretrovirals for reducing the risk of mother-to-child transmission of HIV infection","author":"Siegfried","year":"2011","journal-title":"Cochrane Database Syst Rev"},{"key":"2023050217525178300_bib3","volume-title":"Pr\u00e9-natal e Puerp\u00e9rio: aten\u00e7\u00e3o qualificada e humanizada \u2013 manual t\u00e9cnico","author":"Minist\u00e9rio da Sa\u00fade (Brasil)","year":"2005"},{"key":"2023050217525178300_bib4","volume-title":"Sa\u00fade sexual e sa\u00fade reprodutiva","author":"Minist\u00e9rio da Sa\u00fade (Brasil)","year":"2013"},{"key":"2023050217525178300_bib5","volume-title":"Protocolo Cl\u00ednico e Diretrizes Terap\u00eauticas para Preven\u00e7\u00e3o da Transmiss\u00e3o Vertical do HIV, S\u00edfilis e Hepatites Virais [Internet]","author":"Minist\u00e9rio da Sa\u00fade (Brasil)","year":"2019"},{"key":"2023050217525178300_bib6","volume-title":"Global guidance on criteria and processes for validation: elimination of mother-to-child transmission (EMTCT) of HIV and syphilis","author":"World Health Organization","year":"2014"},{"key":"2023050217525178300_bib7","article-title":"WHO validates elimination of mother to child transmission of HIV and syphilis in Cuba","author":"World Health Organization","year":"2015"},{"key":"2023050217525178300_bib8","article-title":"Indicadores e dados b\u00e1sicos do HIV\/AIDS - nos munic\u00edpios brasileiros 2021","author":"Minist\u00e9rio da Sa\u00fade (Brasil)"},{"key":"2023050217525178300_bib9","article-title":"Indicadores e dados b\u00e1sicos da s\u00edfilis nos munic\u00edpios brasileiros 2021","author":"Minist\u00e9rio da Sa\u00fade (Brasil)"},{"issue":"121","key":"2023050217525178300_bib10","first-page":"109","article-title":"Portaria n.o 1.459, de 24 de junho de 2011. DOU Se\u00e7\u00e3o","volume":"1","author":"Minist\u00e9rio da Sa\u00fade (Brasil)","year":"2011"},{"key":"2023050217525178300_bib11","article-title":"Elimination of mother-to-child transmission of HIV and syphilis in the Americas","author":"Pan American Health Organization","year":"2017"},{"key":"2023050217525178300_bib12","volume-title":"A estrat\u00e9gia de implanta\u00e7\u00e3o do Plano Diretor da Aten\u00e7\u00e3o Prim\u00e1ria em Sa\u00fade PDAPS - Juiz de Fora","author":"Prefeitura de Juiz de Fora","year":"2014"},{"issue":"spe1","key":"2023050217525178300_bib13","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1590\/0103-11042018s102","article-title":"Estrat\u00e9gia Sa\u00fade da Fam\u00edlia, um forte modelo de Aten\u00e7\u00e3o Prim\u00e1ria \u00e0 Sa\u00fade que traz resultados","volume":"42","author":"Macinko","year":"2018","journal-title":"Sa\u00fade Em Debate"},{"issue":"7","key":"2023050217525178300_bib14","doi-asserted-by":"crossref","first-page":"2105","DOI":"10.1590\/1413-81232015207.10742014","article-title":"\u00cdndices sint\u00e9ticos de vulnerabilidade: uma revis\u00e3o integrativa de literatura","volume":"20","author":"Schumann","journal-title":"Ci\u00eanc Sa\u00fade Colet. 2015;"},{"issue":"1","key":"2023050217525178300_bib15","first-page":"e2019019","article-title":"Pr\u00e9-natal no Brasil: estudo transversal do Programa de Melhoria do Acesso e da Qualidade da Aten\u00e7\u00e3o B\u00e1sica","volume":"29","author":"Neves","year":"2014","journal-title":"Epidemiol Serv Sa\u00fade"},{"issue":"1","key":"2023050217525178300_bib16","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1590\/1806-93042019000100003","article-title":"Economic and racial inequalities in the prenatal care of pregnant teenagers in Brazil, 2011-2012","volume":"19","author":"Almeida","year":"2019","journal-title":"Rev Bras Sa\u00fade Materno Infant"},{"issue":"3","key":"2023050217525178300_bib17","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1590\/1413-81232014193.16042013","article-title":"Fatores associados \u00e0 infec\u00e7\u00e3o pelo HIV\/AIDS entre adolescentes e adultos jovens matriculados em Centro de Testagem e Aconselhamento no Estado da Bahia, Brasil","volume":"19","author":"Pereira","year":"2014","journal-title":"Ci\u00eanc Sa\u00fade Coletiva"},{"issue":"57","key":"2023050217525178300_bib18","first-page":"107","article-title":"S\u00edfilis na gestante e cong\u00eanita: perfil epidemiol\u00f3gico e prevalencia","volume":"19","author":"Silva","year":"2020","journal-title":"Enferm Glob"},{"issue":"6","key":"2023050217525178300_bib19","doi-asserted-by":"crossref","first-page":"1965","DOI":"10.1590\/1413-81232015216.06162015","article-title":"Aten\u00e7\u00e3o pr\u00e9-natal e fatores de risco associados \u00e0 prematuridade e baixo peso ao nascer em capital do nordeste brasileiro","volume":"21","author":"Gonzaga","year":"2016","journal-title":"Ci\u00eanc Sa\u00fade Colet"},{"issue":"2","key":"2023050217525178300_bib20","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1590\/S1519-38292013000200002","article-title":"Avalia\u00e7\u00e3o da qualidade da aten\u00e7\u00e3o pr\u00e9-natal dentre gestantes com e sem hist\u00f3ria de prematuridade no Sistema \u00danico de Sa\u00fade no Rio de Janeiro, Brazil","volume":"13","author":"Vettore","year":"2013","journal-title":"Rev Bras Sa\u00fade Materno Infant"},{"issue":"5","key":"2023050217525178300_bib21","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1590\/1413-81232020255.32852019","article-title":"Desigualdades sociais e geogr\u00e1ficas no desempenho da assist\u00eancia pr\u00e9-natal de uma Regi\u00e3o Metropolitana do Brasil","volume":"25","author":"Esposti","year":"2020","journal-title":"Ci\u00eanc Sa\u00fade Colet"},{"key":"2023050217525178300_bib22","article-title":"An\u00e1lise da qualidade da assist\u00eancia pr\u00e9-natal na aten\u00e7\u00e3o prim\u00e1ria \u00e0 sa\u00fade no munic\u00edpio de jo\u00e3o Pessoa\/PB","author":"Silva","year":"2018"},{"issue":"5","key":"2023050217525178300_bib23","doi-asserted-by":"crossref","DOI":"10.1590\/S0034-8910.2014048005114","article-title":"Prevalence of syphilis in pregnancy and prenatal syphilis testing in Brazil: birth in Brazil study","volume":"48","author":"Domingues","year":"2014;","journal-title":"Rev Sa\u00fade P\u00fabl"},{"issue":"110-E","key":"2023050217525178300_bib24","first-page":"4","article-title":"Portaria n.o 569, de 1 de junho de 2000","volume":"138","author":"Minist\u00e9rio da Sa\u00fade (Brasil)","year":"2000","journal-title":"DOU Se\u00e7\u00e3o"},{"issue":"suppl 1","key":"2023050217525178300_bib25","doi-asserted-by":"crossref","first-page":"S85","DOI":"10.1590\/0102-311X00126013","article-title":"Assist\u00eancia pr\u00e9-natal no Brasil","volume":"30","author":"Viellas","year":"2014","journal-title":"Cad Sa\u00fade P\u00fablica"},{"issue":"1","key":"2023050217525178300_bib26","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1186\/1471-2458-13-206","article-title":"Prevalence and factors associated with syphilis in parturient women in northeast Brazil","volume":"13","author":"Ara\u00fajo","year":"2013","journal-title":"BMC Public Health"},{"key":"2023050217525178300_bib27","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1590\/1980-549720200012","article-title":"N\u00e3o realiza\u00e7\u00e3o de teste sorol\u00f3gico para s\u00edfilis durante o pr\u00e9-natal: preval\u00eancia e fatores associados","volume":"23","author":"Cesar","year":"2020","journal-title":"Rev Bras Epidemiol"},{"key":"2023050217525178300_bib28","volume-title":"Avalia\u00e7\u00e3o das a\u00e7\u00f5es de preven\u00e7\u00e3o da transmiss\u00e3o de m\u00e3e para filho da s\u00edfilis, na assist\u00eancia pr\u00e9-natal, na Aten\u00e7\u00e3o Prim\u00e1ria \u00e0 Sa\u00fade no munic\u00edpio de Juiz de Fora-MG. Thesis","author":"Guedes","year":"2020"},{"key":"2023050217525178300_bib29","first-page":"410","volume-title":"Agreement of antenatal care indicators from self-reported questionnaire and the antenatal care card of women in the 2015 Pelotas birth cohort","author":"Mor\u00f3n-Duarte","year":"2019"},{"issue":"5","key":"2023050217525178300_bib30","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1590\/S1413-81232013000500019","article-title":"Manejo da s\u00edfilis na gesta\u00e7\u00e3o: conhecimentos, pr\u00e1ticas e atitudes dos profissionais pr\u00e9-natalistas da rede SUS do munic\u00edpio do Rio de Janeiro","volume":"18","author":"Domingues","year":"2013","journal-title":"Ci\u00eanc Sa\u00fade Colet"}],"container-title":["Transactions of The Royal Society of Tropical Medicine and Hygiene"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/trstmh\/article-pdf\/117\/5\/336\/50171777\/trac113.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/trstmh\/article-pdf\/117\/5\/336\/50171777\/trac113.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,2]],"date-time":"2023-05-02T18:35:23Z","timestamp":1683052523000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/trstmh\/article\/117\/5\/336\/6891090"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,13]]},"references-count":30,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2022,12,13]]},"published-print":{"date-parts":[[2023,5,2]]}},"URL":"https:\/\/doi.org\/10.1093\/trstmh\/trac113","relation":{},"ISSN":["0035-9203","1878-3503"],"issn-type":[{"value":"0035-9203","type":"print"},{"value":"1878-3503","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,5]]},"published":{"date-parts":[[2022,12,13]]}}}