{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T00:41:56Z","timestamp":1779928916125,"version":"3.53.1"},"reference-count":5,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2023,9,18]],"date-time":"2023-09-18T00:00:00Z","timestamp":1694995200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,12,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Cystic echinococcosis (CE) is attributable to Echinococcus granulosus metacestodes. Ultrasound examinations enable a stage-specific approach to CE management. However, this approach is not often applied in endemic areas, which include Kazakhstan.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We collected clinical and ultrasound data on CE pediatric patients seen at a national referral surgical center in Almaty, Kazakhstan, during 2015\u20132020.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>We included 49 patients, and 79 cysts that were all surgically treated. All but one patient carried active cysts (CE1-CE3 stages). Twenty-six (53.2%) did not receive albendazole postsurgery. Children with CE1 and CE3a cysts underwent surgery, while the use of albendazole and percutaneous drainage were advised upon by experts.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>A stage-specific approach to CE management in Kazakhstan is urgent, especially in the pediatric population. The rate of active cysts suggests continuing transmission of CE.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/trstmh\/trad065","type":"journal-article","created":{"date-parts":[[2023,9,18]],"date-time":"2023-09-18T10:07:15Z","timestamp":1695031635000},"page":"875-877","source":"Crossref","is-referenced-by-count":3,"title":["The high burden of pediatric cystic echinococcosis in Kazakhstan: epidemiological and clinical consequences"],"prefix":"10.1093","volume":"117","author":[{"given":"Gaukhar","family":"Doszhanova","sequence":"first","affiliation":[{"name":"Department of Infectious and Tropical Diseases, Asfendyiarov Kazakh National Medical University , 94 Tole Bi Street, Almaty 050012 , Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8959-1403","authenticated-orcid":false,"given":"Agnese","family":"Colpani","sequence":"additional","affiliation":[{"name":"Unit of Infectious Diseases, Department of Medicine, Surgery and Pharmacy, University of Sassari , Sassari 07100 , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amangul","family":"Duisenova","sequence":"additional","affiliation":[{"name":"Department of Infectious and Tropical Diseases, Asfendyiarov Kazakh National Medical University , 94 Tole Bi Street, Almaty 050012 , Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"De Vito","sequence":"additional","affiliation":[{"name":"Unit of Infectious Diseases, Department of Medicine, Surgery and Pharmacy, University of Sassari , Sassari 07100 , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhamilya","family":"Zholdybay","sequence":"additional","affiliation":[{"name":"Department of Visual Diagnostics, Asfendiyarov Kazakh National Medical University , 94 Tole Bi Street, Almaty 050012 , Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konrad","family":"Juszkiewicz","sequence":"additional","affiliation":[{"name":"Department of Infectious and Tropical Diseases, Asfendyiarov Kazakh National Medical University , 94 Tole Bi Street, Almaty 050012 , Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8437-6627","authenticated-orcid":false,"given":"Enrico","family":"Brunetti","sequence":"additional","affiliation":[{"name":"WHO-Collaborating Center for the Clinical Management of Cystic Echinoccocosis, San Matteo Hospital Foundation , Pavia 27100 , Italy"},{"name":"Department of Clinical-Surgical, Diagnostic and Pediatric Sciences, University of Pavia , Pavia 27100 , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adyl","family":"Katarbayev","sequence":"additional","affiliation":[{"name":"Department of Children Infectious Diseases, Asfendiyarov Kazakh National Medical University , 94 Tole Bi Street, Almaty 050012 , Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shokan","family":"Kaniyev","sequence":"additional","affiliation":[{"name":"Syzganov National Institute of Surgery , 62 Zheltoksan Street, Almaty 050004 , Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhanar","family":"Zhakenova","sequence":"additional","affiliation":[{"name":"Department of Visual Diagnostics, Asfendiyarov Kazakh National Medical University , 94 Tole Bi Street, Almaty 050012 , Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tommaso","family":"Manciulli","sequence":"additional","affiliation":[{"name":"WHO-Collaborating Center for the Clinical Management of Cystic Echinoccocosis, San Matteo Hospital Foundation , Pavia 27100 , Italy"},{"name":"Department of Clinical and Experimental Medicine, University of Florence , Florence 50121 , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aigerim","family":"Mustapayeva","sequence":"additional","affiliation":[{"name":"Department of Visual Diagnostics, Asfendiyarov Kazakh National Medical University , 94 Tole Bi Street, Almaty 050012 , Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,9,18]]},"reference":[{"key":"2023120418290160400_bib1","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/bs.apar.2016.11.001","article-title":"Global distribution of alveolar and cystic echinococcosis","volume":"95","author":"Deplazes","year":"2017","journal-title":"Adv Parasitol"},{"key":"2023120418290160400_bib2","volume-title":"Ending the Neglect to Attain the Sustainable Development Goals: A Road Map for Neglected Tropical Diseases 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