{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T11:50:09Z","timestamp":1740138609105,"version":"3.37.3"},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2024,1,16]],"date-time":"2024-01-16T00:00:00Z","timestamp":1705363200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/501100002385","name":"Ministry of Higher Education","doi-asserted-by":"publisher","award":["MO002-2019"],"award-info":[{"award-number":["MO002-2019"]}],"id":[{"id":"10.13039\/501100002385","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Higher Institution Centre of Excellence","award":["TIDREC-2023"],"award-info":[{"award-number":["TIDREC-2023"]}]},{"DOI":"10.13039\/501100021375","name":"University of Malaya Centre of Excellence","doi-asserted-by":"publisher","award":["UM.00000188\/HGA.GV"],"award-info":[{"award-number":["UM.00000188\/HGA.GV"]}],"id":[{"id":"10.13039\/501100021375","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Research University","award":["RU002-2019"],"award-info":[{"award-number":["RU002-2019"]}]},{"name":"Impact Oriented Interdisciplinary Research","award":["IIRG002A-2020SAH"],"award-info":[{"award-number":["IIRG002A-2020SAH"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Mosquito-borne diseases pose a significant global public health threat, with Malaysia's Klang Valley experiencing numerous outbreaks in densely populated urban areas.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>This study aimed to estimate the seroprevalence of anti-dengue and anti-chikungunya antibodies among urban refugees in the Klang Valley, Malaysia, and identify associated risk factors.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>High seroprevalence of anti-dengue immunoglobulin G (IgG) and IgM (60.0% [confidence interval {CI} 55.39 to 64.48] and 9.2% [CI 6.77 to 12.25], respectively) were observed among refugees &amp;gt;18\u00a0years of age (\u03c722=11.720, p=0.003), Kachin ethnicity (\u03c728=72.253, p&amp;lt;0.001), without formal education (\u03c721=3.856, p=0.050), homes near waste disposal sites (\u03c721=10.378, p=0.001) and refugees who have experienced flooding (\u03c721=5.460, p=0.019). Meanwhile, the overall seroprevalence of anti-chikungunya IgG and IgM was 9.7% (CI 7.15 to 12.73) and 10.8% (CI 8.09 to 13.93), respectively, with ages 12\u201318\u00a0years (\u03c722=6.075, p=0.048), Rohingya ethnicity (\u03c728=31.631, p&amp;lt;0.001) and homes close to waste disposal sites (\u03c721=3.912, p=0.048) being significant risk factors. Results showed a link to poor environmental living conditions, with an increase in the vector population with higher availability of breeding sites and thus exposure to dengue and chikungunya virus.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Health education among the community is the key to disease prevention, as there are no specific antiviral drugs for treatment and limited vaccine availability.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/trstmh\/trad097","type":"journal-article","created":{"date-parts":[[2024,1,16]],"date-time":"2024-01-16T10:18:12Z","timestamp":1705400292000},"page":"328-335","source":"Crossref","is-referenced-by-count":0,"title":["Seroprevalence of dengue and chikungunya viruses among urban refugees in Klang Valley, Malaysia"],"prefix":"10.1093","volume":"118","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1457-2758","authenticated-orcid":false,"given":"Norhidayu","family":"Sahimin","sequence":"first","affiliation":[{"name":"Tropical Infectious Diseases Research and Education Centre (TIDREC), Universiti Malaya , 50603 Kuala Lumpur , Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhao Xuan","family":"Low","sequence":"additional","affiliation":[{"name":"Tropical Infectious Diseases Research and Education Centre (TIDREC), Universiti Malaya , 50603 Kuala Lumpur , Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pouya","family":"Hassandarvish","sequence":"additional","affiliation":[{"name":"Tropical Infectious Diseases Research and Education Centre (TIDREC), Universiti Malaya , 50603 Kuala Lumpur , Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Izzah Ruzana","family":"Mohd Hanapi","sequence":"additional","affiliation":[{"name":"Institute of Biological Sciences, Faculty of Science, Universiti Malaya , 50603 Kuala Lumpur , Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siti Nursheena","family":"Mohd Zain","sequence":"additional","affiliation":[{"name":"Institute of Biological Sciences, Faculty of Science, Universiti Malaya , 50603 Kuala Lumpur , Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hasmawati","family":"Yahaya","sequence":"additional","affiliation":[{"name":"Tropical Infectious Diseases Research and Education Centre (TIDREC), Universiti Malaya , 50603 Kuala Lumpur , Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sazaly","family":"Abu Bakar","sequence":"additional","affiliation":[{"name":"Tropical Infectious Diseases Research and Education Centre (TIDREC), Universiti Malaya , 50603 Kuala Lumpur , 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