{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T03:20:26Z","timestamp":1792466426682,"version":"4.5.0"},"reference-count":40,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2024,5,20]],"date-time":"2024-05-20T00:00:00Z","timestamp":1716163200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/501100009104","name":"Department of Health Research, India","doi-asserted-by":"publisher","award":["R.11013\/57\/2021-GIA\/HR"],"award-info":[{"award-number":["R.11013\/57\/2021-GIA\/HR"]}],"id":[{"id":"10.13039\/501100009104","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,9,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Globally, India has a high zoonotic disease burden and lacks surveillance data in humans and animals. Rodents are known reservoirs for many zoonotic diseases and their synanthropic behavior poses a great public health threat.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>In this study, trapped rodents\/shrews from randomly selected villages within Puducherry, India, and their ectoparasites were screened for zoonotic pathogens, namely, Orientia tsutsugamushi, other pathogenic rickettsiae, Leptospira spp., Cryptosporidium spp., Coxiella burnetii and methicillin-resistant Staphylococcus aureus (MRSA) using conventional PCR. A total of 58 rodents\/shrews were trapped from 11 villages. The species trapped were Suncus murinus (49\/58, 84.48%), Rattus rattus (8\/58, 13.79%) and Rattus norvegicus (1\/58, 1.72%). All ectoparasites collected were identified as mites and its infestation rate was 46.55% (27\/58).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Real-time PCR targeting the 47 kDa gene of O. tsutsugamushi revealed positivity in one rodent and one shrew (3.45%) and two mite pools (7.41%). Conventional PCR targeting the 56 kDa gene revealed positivity in one shrew and two mite pools and the phylogenetic analysis of all three amplicons indicated the circulation of the Gilliam-related serotype. MRSA was detected in the alimentary tract of a shrew (1\/32, 3.13%). Leptospira spp., Rickettsia, Cryptosporidium spp. and Co. burnetii tested negative.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>The detection of zoonotic pathogens within reservoir hosts and vectors poses a risk of transmission to humans. This study signifies the need for zoonotic pathogen surveillance in synanthropic rodents\/shrews.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/trstmh\/trae033","type":"journal-article","created":{"date-parts":[[2024,5,20]],"date-time":"2024-05-20T18:40:45Z","timestamp":1716230445000},"page":"616-624","source":"Crossref","is-referenced-by-count":4,"title":["A molecular survey of zoonotic pathogens of public health importance in rodents\/shrews and their ectoparasites trapped in Puducherry, India"],"prefix":"10.1093","volume":"118","author":[{"given":"Brenna","family":"Eikenbary","sequence":"first","affiliation":[{"name":"Department of Global Health, Georgetown University , Washington DC, 20057 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0638-9590","authenticated-orcid":false,"given":"Panneer","family":"Devaraju","sequence":"additional","affiliation":[{"name":"Unit of One Health, ICMR-Vector Control Research Centre 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