{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T11:50:15Z","timestamp":1740138615579,"version":"3.37.3"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2024,11,6]],"date-time":"2024-11-06T00:00:00Z","timestamp":1730851200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/501100010834","name":"Education Department of Hainan Province","doi-asserted-by":"publisher","award":["Hnky2023ZD-9"],"award-info":[{"award-number":["Hnky2023ZD-9"]}],"id":[{"id":"10.13039\/501100010834","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Hainan Province Clinical Medical Center","award":["QWYH202175"],"award-info":[{"award-number":["QWYH202175"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,2,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>The overlapping clinical and radiographic features of pulmonary melioidosis and lung cancer present diagnostic challenges to healthcare providers in endemic settings.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We compared the clinical, laboratory and imaging characteristics of 19 pulmonary melioidosis cases with those of 15 cases of small cell lung cancer (SCLC) and 17 cases of non-small cell lung cancer (NSCLC).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Compared with SCLC\/NSCLC cases, those with pulmonary melioidosis were more likely to have diabetes, have fever, neutrophilia and leukocytosis on presentation (p&amp;lt;0.05). While certain CT imaging features were shared between pulmonary melioidosis and SCLC (\u2018frozen mediastinum sign\u2019, \u2018vascular encasement sign\u2019), extensive liquefactive necrosis, uneven ring-enhancement, circular lesions and \u2018air-bubble\u2019 signs were more commonly seen in pulmonary melioidosis cases than in those with SCLC\/NSCLC (p&amp;lt;0.05).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Despite the similarities in presentation of pulmonary melioidosis, SCLC and NSCLC, several clinical, laboratory and imaging factors may help delineate these diagnoses and improve patient care.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/trstmh\/trae089","type":"journal-article","created":{"date-parts":[[2024,11,6]],"date-time":"2024-11-06T09:35:21Z","timestamp":1730885721000},"page":"125-134","source":"Crossref","is-referenced-by-count":0,"title":["Pulmonary melioidosis mimicking lung cancer: a diagnostic challenge"],"prefix":"10.1093","volume":"119","author":[{"given":"Xiaohong","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Radiology, The First Affiliated Hospital of Hainan Medical University , 31 Longhua Road, Haikou ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhuopeng","family":"Ying","sequence":"additional","affiliation":[{"name":"Department of Radiology, The First Affiliated Hospital of Hainan Medical University , 31 Longhua Road, Haikou ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9093-0599","authenticated-orcid":false,"given":"Yuefu","family":"Zhan","sequence":"additional","affiliation":[{"name":"Department of Radiology, The Third People's Hospital of Shenzhen Longgang District , 278 Songbai Road, Shenzhen ,","place":["China"]},{"name":"Department of Radiology, Hainan Women's and Children's Hospital , 15 Longkun South Road, Haikou ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianqiang","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Radiology, The First Affiliated Hospital of Hainan Medical University , 31 Longhua Road, Haikou ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,11,6]]},"reference":[{"issue":"2","key":"2025020409230499700_bib1","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1128\/CMR.18.2.383-416.2005","article-title":"Melioidosis: epidemiology, pathophysiology, and management","volume":"18","author":"Cheng","year":"2005","journal-title":"Clin Microbiol Rev"},{"issue":"10278","key":"2025020409230499700_bib2","doi-asserted-by":"crossref","first-page":"e8","DOI":"10.1016\/S0140-6736(21)00200-2","article-title":"Mediastinal melioidosis masquerading as malignancy of the 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