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Strongyloides stercoralis is a soil-transmitted opportunistic pathogenic parasite that can cause strongyloidiasis in both humans and animals, potentially leading to severe disease or even death in immunocompromised hosts. This article outlines the epidemiological status, diagnosis and treatment methods of strongyloidiasis. It also discusses effective response strategies based on the One Health approach to actively cope with the zoonotic risk of S. stercoralis and promote human health development.<\/jats:p>","DOI":"10.1093\/trstmh\/traf003","type":"journal-article","created":{"date-parts":[[2025,1,10]],"date-time":"2025-01-10T12:17:49Z","timestamp":1736511469000},"page":"679-687","source":"Crossref","is-referenced-by-count":0,"title":["The One Health approach to <i>Strongyloides stercoralis<\/i>"],"prefix":"10.1093","volume":"119","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-6754-4371","authenticated-orcid":false,"given":"Jiayin","family":"Lyu","sequence":"first","affiliation":[{"name":"Guangxi Medical University Department of Parasitology, School of Basic Medicinal Sciences, , Nanning 530021 ,","place":["China"]},{"name":"Key Laboratory of Basic Research on Regional Diseases (Guangxi Medical University) , Education Department of Guangxi Zhuang Autonomous Region, Nanning 530021 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