{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T03:43:45Z","timestamp":1770090225099,"version":"3.49.0"},"reference-count":29,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T00:00:00Z","timestamp":1758672000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Department of Medical Research, Myanmar"},{"name":"Institute of Tropical Medicine, Nagasaki University","award":["2023-Ippan 11"],"award-info":[{"award-number":["2023-Ippan 11"]}]},{"name":"Japan Agency of Medical Research and Development","award":["JP223fa627004"],"award-info":[{"award-number":["JP223fa627004"]}]},{"name":"Japan Agency of Medical Research and Development","award":["JP253fa627004"],"award-info":[{"award-number":["JP253fa627004"]}]},{"name":"Japan Agency of Medical Research and Development","award":["JP24fk0108656"],"award-info":[{"award-number":["JP24fk0108656"]}]},{"name":"Japan Agency of Medical Research and Development","award":["24jm0210114h0001"],"award-info":[{"award-number":["24jm0210114h0001"]}]},{"name":"Japanese Society for Promotion of Science KAKENHI","award":["24K10246"],"award-info":[{"award-number":["24K10246"]}]},{"name":"Japanese Society for Promotion of Science KAKENHI","award":["24K02288"],"award-info":[{"award-number":["24K02288"]}]},{"name":"SDGs Research Project of Shimane University"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,2,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Zika virus (ZIKV) is a mosquito-borne flavivirus mainly transmitted by Aedes aegypti and Aedes albopictus. While well-studied in the Americas, data from Southeast Asia, especially Myanmar, remain limited. This study assessed ZIKV infection among dengue-suspected patients in Yangon, Myanmar, from 2017 to 2019.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a cross-sectional retrospective study that collected serum samples from 1162 clinically dengue-suspected patients. Reverse transcription quantitative polymerase chain reaction (RT-qPCR) was used to detect ZIKV RNA and serological assays were used to identify ZIKV-specific immunoglobulin M (IgM), IgG and neutralizing antibodies. The age, gender, clinical manifestations and coinfections with dengue virus (DENV) were determined.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of the 1162 samples, 23 (2.0%) were positive for ZIKV by RT-qPCR. Among these, nine samples showed coinfection with DENV: four with DENV-1, two with DENV-3 and three with DENV-4. Of the 111 (9.6%) samples that tested positive for ZIKV IgM, 11 (9.9%) had neutralizing antibodies against ZIKV, with 9 (8.1%) confirmed as ZIKV positive and 2 (1.8%) classified as probable cases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our study reported that 32 cases (2.8%) were confirmed as ZIKV infections by molecular and serological detection. The findings underscore the need for improved surveillance, diagnostic accuracy and public health interventions to mitigate the impact of ZIKV.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/trstmh\/traf102","type":"journal-article","created":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T11:35:57Z","timestamp":1757417757000},"page":"118-125","source":"Crossref","is-referenced-by-count":0,"title":["Epidemiological insights into the co-circulation of Zika and dengue viruses in Yangon, Myanmar (2017\u20132019)"],"prefix":"10.1093","volume":"120","author":[{"given":"Maurine Mumo","family":"Mutua","sequence":"first","affiliation":[{"name":"Institute of Tropical Medicine, Nagasaki University Department of Virology, , Nagasaki 852-8523 ,","place":["Japan"]},{"name":"Kenya Medical Research Institute Graduate School Department of Health, , Nairobi 54840-00200 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852-8523 ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Htin","family":"Lin","sequence":"additional","affiliation":[{"name":"Ministry of Health Department of Medical Research, , Yangon 11191 ,","place":["Myanmar"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Merveille","family":"Kapandji","sequence":"additional","affiliation":[{"name":"Institute of Tropical Medicine, Nagasaki University Department of Virology, , Nagasaki 852-8523 ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shingo","family":"Inoue","sequence":"additional","affiliation":[{"name":"Nagasaki University, Kenya Research Station Department of Microbiology, , Nairobi 19993-00202 ,","place":["Kenya"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyaw Zin","family":"Thant","sequence":"additional","affiliation":[{"name":"Myanmar Academy of Medical Science , Yangon 11201 ,","place":["Myanmar"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuki","family":"Takamatsu","sequence":"additional","affiliation":[{"name":"Institute of Tropical Medicine, Nagasaki University Department of Virology, , Nagasaki 852-8523 ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wah Wah","family":"Aung","sequence":"additional","affiliation":[{"name":"Ministry of Health Department of Medical Research, , Yangon 11191 ,","place":["Myanmar"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aye Aye","family":"Khin","sequence":"additional","affiliation":[{"name":"Ministry of Health Department of Medical Research, , Yangon 11191 ,","place":["Myanmar"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hlaing Myat","family":"Thu","sequence":"additional","affiliation":[{"name":"Ministry of Health Department of Medical Research, , Yangon 11191 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