{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T17:00:55Z","timestamp":1780938055262,"version":"3.54.1"},"reference-count":22,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T00:00:00Z","timestamp":1773273600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,6,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Fasciola infection is an emerging cause of liver abscess in children, yet pediatric data from Vietnam remain limited. This study aimed to describe the clinical characteristics, laboratory findings and treatment outcomes of liver abscess caused by Fasciola in Vietnamese children.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective study was conducted on 25 pediatric patients with Fasciola-related liver abscess at Children\u2019s Hospital 2. Treatment consisted of triclabendazole at 10 mg\/kg per dose, given twice every 12\u201324 h and administered after meals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The most common clinical features were right upper quadrant abdominal pain (95%), hepatomegaly (68%) and vomiting (24%). The predominant laboratory abnormalities included neutrophilia (72%), elevated C-reactive protein levels (68%) and leukocytosis (56%). Ultrasonography revealed that most patients had a single abscess (75%), predominantly located in the right hepatic lobe (58.3%), with an abscess diameter \u22645 cm (70.8%). One case was not detected on ultrasound and required CT for diagnosis. The treatment success rate with triclabendazole was 96.0%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In children presenting with clinical features suggestive of Fasciola-related liver abscess, ultrasonography is a routine and effective screening tool for early detection. Triclabendazole is a safe and effective treatment for Fasciola-related liver abscess in pediatric patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/trstmh\/trag021","type":"journal-article","created":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T12:32:14Z","timestamp":1770640334000},"page":"617-622","source":"Crossref","is-referenced-by-count":0,"title":["Liver abscess caused by\n                    <i>Fasciola<\/i>\n                    in children in southern Vietnam"],"prefix":"10.1093","volume":"120","author":[{"given":"Khoi H","family":"Ha","sequence":"first","affiliation":[{"name":"Phong Kham Nhi Dr Thieu, 579A Do Xuan Hop Street, Phuoc Long Ward , Thu Duc City, Ho Chi Minh City 70000 ,","place":["Vietnam"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-4106-952X","authenticated-orcid":false,"given":"Duy K H","family":"Dang","sequence":"additional","affiliation":[{"name":"Hong Bang International University Department of Pediatrics, Faculty of Medicine, , 215 Dien Bien Phu Street, Gia Dinh Ward, Ho Chi Minh City 716000 ,","place":["Vietnam"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tri T","family":"Tran","sequence":"additional","affiliation":[{"name":"Children\u2019s Hospital 2 Hepatobiliary\u2013Pancreatic and Liver Transplantation Department, , 14 Ly Tu Trong Street, Sai Gon Ward, Ho Chi Minh City 710000 ,","place":["Vietnam"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phu D","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Ear Nose Throat Hospital , 155B Tran Quoc Thao Street, Nhieu Loc Ward, Ho Chi Minh City 700000 ,","place":["Vietnam"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huynh N","family":"Do","sequence":"additional","affiliation":[{"name":"Hong Bang International University Department of Pediatrics, Faculty of Medicine, , 215 Dien Bien Phu Street, Gia Dinh Ward, Ho Chi Minh City 716000 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