{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T17:01:04Z","timestamp":1780938064221,"version":"3.54.1"},"reference-count":5,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T00:00:00Z","timestamp":1773360000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["220818\/Z\/20\/Z"],"award-info":[{"award-number":["220818\/Z\/20\/Z"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,6,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Public health monitoring of schistosomiasis needs appropriate field-based technology, so to expand this portfolio, we conducted a first pilot assessment of point-of-care differential white blood cell count analysers. In total, 120 Malawian primary school children were examined with six key haematological parameters recorded. A notable proportion had abnormal differential white blood cell profiles with eosinophilia (48.3%) positively associated with schistosomiasis (OR 3.2, 95% CI 1.3 to 7.7). Whilst costs of equipment and associated tests were non-trivial, both machine performance and haematological information gained were satisfactory. To improve monitoring of schistosomiasis-associated pathologies, the inclusion of differential white blood cell count technology screening appears sensible.<\/jats:p>","DOI":"10.1093\/trstmh\/trag025","type":"journal-article","created":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T12:34:05Z","timestamp":1771677245000},"page":"591-594","source":"Crossref","is-referenced-by-count":0,"title":["Pilot assessment of point-of-care differential white blood cell count analysers in schoolchildren with schistosomiasis"],"prefix":"10.1093","volume":"120","author":[{"given":"Sarah","family":"Rollason","sequence":"first","affiliation":[{"name":"School of Biosciences, Cardiff University , Cardiff CF10 3AX ,","place":["UK"]},{"name":"Tropical Disease Biology, Liverpool School of Tropical Medicine , Liverpool L3 5QA ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordan","family":"White","sequence":"additional","affiliation":[{"name":"Tropical Disease Biology, Liverpool School of Tropical Medicine , Liverpool L3 5QA ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Makaula","sequence":"additional","affiliation":[{"name":"Malawi Liverpool Wellcome Research Programme, Queen Elizabeth Central Hospital Campus , Chipatala Avenue, P.O. Box 30096 Chichiri, Blantyre ,","place":["Malawi"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sekeleghe A","family":"Kayuni","sequence":"additional","affiliation":[{"name":"Malawi Liverpool Wellcome Research Programme, Queen Elizabeth Central Hospital Campus , Chipatala Avenue, P.O. Box 30096 Chichiri, Blantyre ,","place":["Malawi"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janelisa","family":"Musaya","sequence":"additional","affiliation":[{"name":"Malawi Liverpool Wellcome Research Programme, Queen Elizabeth Central Hospital Campus , Chipatala Avenue, P.O. Box 30096 Chichiri, Blantyre ,","place":["Malawi"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9370-3420","authenticated-orcid":false,"given":"J Russell","family":"Stothard","sequence":"additional","affiliation":[{"name":"Tropical Disease Biology, Liverpool School of Tropical Medicine , Liverpool L3 5QA ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,3,13]]},"reference":[{"key":"2026060812260296600_bib1","volume-title":"WHO Guideline on Control and Elimination of human Schistosomiasis","author":"World Health Organisation","year":"2022"},{"issue":"5","key":"2026060812260296600_bib2","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1111\/ijlh.13076","article-title":"Full blood count and white cell differential count reference ranges obtained from a healthy urban South African population residing in the Western Cape of South Africa","volume":"41","author":"Smit","year":"2019","journal-title":"Int J Lab Hematol"},{"issue":"1","key":"2026060812260296600_bib3","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1186\/s40249-020-00736-w","article-title":"An outbreak of intestinal schistosomiasis, alongside increasing urogenital schistosomiasis prevalence, in primary school children on the shoreline of Lake Malawi, Mangochi District, Malawi","volume":"9","author":"Kayuni","year":"2020","journal-title":"Infect Dis Poverty"},{"key":"2026060812260296600_bib4","doi-asserted-by":"crossref","DOI":"10.1002\/9781444345186.app2","article-title":"Pediatric normal laboratory values","volume-title":"Gregory\u2019s Pediatric Anaesthesia","author":"Andropoulos","year":"2012"},{"issue":"4","key":"2026060812260296600_bib5","first-page":"243","article-title":"Local reference ranges for full blood count and CD4 lymphocyte count testing","volume":"99","author":"Lawrie","year":"2009","journal-title":"S Afr Med J"}],"container-title":["Transactions of The Royal Society of Tropical Medicine and Hygiene"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/trstmh\/article-pdf\/120\/6\/591\/67335288\/trag025.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/trstmh\/article-pdf\/120\/6\/591\/67335288\/trag025.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T16:26:10Z","timestamp":1780935970000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/trstmh\/article\/120\/6\/591\/8518709"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,13]]},"references-count":5,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2026,3,13]]},"published-print":{"date-parts":[[2026,6,8]]}},"URL":"https:\/\/doi.org\/10.1093\/trstmh\/trag025","relation":{},"ISSN":["0035-9203","1878-3503"],"issn-type":[{"value":"0035-9203","type":"print"},{"value":"1878-3503","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,6]]},"published":{"date-parts":[[2026,3,13]]}}}