{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T14:13:57Z","timestamp":1783433637277,"version":"3.54.6"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T00:00:00Z","timestamp":1776988800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["GNT1124130"],"award-info":[{"award-number":["GNT1124130"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100025520","name":"Medical Research Future Fund","doi-asserted-by":"publisher","award":["GNT1161627"],"award-info":[{"award-number":["GNT1161627"]}],"id":[{"id":"10.13039\/501100025520","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,7,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>There are scant and variable data concerning the incidence of malaria in infants in endemic areas. This study evaluated the impact of maternal antimalarial treatment given postpartum on malaria incidence and growth\/development in infants from coastal Papua New Guinea (PNG).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In an open-label, randomised controlled trial conducted in Madang Province, PNG, 183 mothers were randomised to no treatment (NT) or to artemisinin combination therapy (ACT) with further random allocation to artemether\u2013lumefantrine or dihydroartemisinin\u2013piperaquine. Their infants were assessed monthly over the next 6\u00a0months including for malaria identified by microscopy and\/or polymerase chain reaction (PCR).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 151 infants who completed study procedures, 2 developed slide-positive malaria (1 Plasmodium falciparum, 1 Plasmodium vivax; 1.3% [95% confidence interval {CI} 0.2 to 5.2]). Three others had PCR-detected infections (two P. falciparum, one P. vivax). The overall 6-month incidence of slide-\/PCR-positive malaria was 3.3% (95% CI 1.2 to 8.0). Four of the five cases occurred in infants whose mothers were randomised to NT. There were no statistically significant between-group differences in infant growth and developmental milestones.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The risk of malaria in early infancy in coastal PNG is low and infections are typically asymptomatic. Postpartum maternal ACT did not influence infant growth or development.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/trstmh\/trag042","type":"journal-article","created":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T11:31:07Z","timestamp":1774956667000},"page":"781-786","source":"Crossref","is-referenced-by-count":0,"title":["Malaria in Papua New Guinean infants: a prespecified analysis of a randomised postpartum antimalarial treatment trial"],"prefix":"10.1093","volume":"120","author":[{"given":"Paula","family":"Tesine","sequence":"first","affiliation":[{"name":"Vector Borne Disease Unit, Papua New Guinea Institute of Medical Research , Madang, Madang Province 511 ,","place":["Papua New Guinea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sze-Ann","family":"Woon","sequence":"additional","affiliation":[{"name":"Medical School, University of Western Australia , Crawley, Western Australia 6009 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Madang Province 511 ,","place":["Papua New Guinea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4334-5351","authenticated-orcid":false,"given":"Laurens","family":"Manning","sequence":"additional","affiliation":[{"name":"Medical School, University of Western Australia , Crawley, Western Australia 6009 ,","place":["Australia"]},{"name":"Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute , 11 Hospital Avenue, Nedlands, Western Australia 6009 ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"HuiJun","family":"Chih","sequence":"additional","affiliation":[{"name":"Curtin School of Population Health, Curtin University , Bentley, Western Australia 6102 ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brioni R","family":"Moore","sequence":"additional","affiliation":[{"name":"Curtin Medical School, Curtin University , Bentley, Western 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