{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T02:49:17Z","timestamp":1761101357303},"reference-count":37,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2019,1,21]],"date-time":"2019-01-21T00:00:00Z","timestamp":1548028800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,6,1]]},"DOI":"10.1093\/trstmh\/try144","type":"journal-article","created":{"date-parts":[[2018,12,20]],"date-time":"2018-12-20T04:21:45Z","timestamp":1545279705000},"page":"320-325","source":"Crossref","is-referenced-by-count":3,"title":["Biological activity of artemisinin-naphthoquine phosphate on Schistosoma haematobium stages and the vector Bulinus truncatus"],"prefix":"10.1093","volume":"113","author":[{"given":"Samar N","family":"El-Beshbishi","sequence":"first","affiliation":[{"name":"Department of Medical Parasitology, Faculty of Medicine, Mansoura University, Mansoura, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samia","family":"El Bardicy","sequence":"additional","affiliation":[{"name":"Department of Medical Malacology, Theodor Bilharz Research Institute, Warrak El Hadar, Imbaba, Giza, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Menerva","family":"Tadros","sequence":"additional","affiliation":[{"name":"Department of Medical Malacology, Theodor Bilharz Research Institute, Warrak El Hadar, Imbaba, Giza, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Magda","family":"Ayoub","sequence":"additional","affiliation":[{"name":"Department of Medical Malacology, Theodor Bilharz Research Institute, Warrak El Hadar, Imbaba, Giza, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amira","family":"Taman","sequence":"additional","affiliation":[{"name":"Department of Medical Parasitology, Faculty of Medicine, Mansoura University, Mansoura, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2019,1,21]]},"reference":[{"issue":"10053","key":"2019061111094879700_try144C1","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1016\/S0140-6736(16)31678-6","article-title":"Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990\u20132015: a systematic analysis for the global burden of disease study 2015","volume":"388","author":"GBD 2015 Disease and Injury Incidence and Prevalence Collaborators","year":"2016","journal-title":"Lancet"},{"issue":"9936","key":"2019061111094879700_try144C2","doi-asserted-by":"crossref","first-page":"2253","DOI":"10.1016\/S0140-6736(13)61949-2","article-title":"Human schistosomiasis","volume":"383","author":"Colley","year":"2014","journal-title":"Lancet"},{"issue":"8","key":"2019061111094879700_try144C3","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/S1473-3099(16)00175-4","article-title":"Outbreak of urogenital schistosomiasis in Corsica (France): an epidemiological case study","volume":"16","author":"Boissier","year":"2016","journal-title":"Lancet Infect Dis"},{"issue":"1","key":"2019061111094879700_try144C4","doi-asserted-by":"crossref","first-page":"e0005524","DOI":"10.1371\/journal.pntd.0005524","article-title":"Cognitive deficits and educational loss in children with schistosome infection\u2014a systematic review and meta-analysis","volume":"12","author":"Ezeamama","year":"2018","journal-title":"PLoS Negl Trop Dis"},{"issue":"1","key":"2019061111094879700_try144C5","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.trstmh.2009.05.013","article-title":"Non-invasive methods to detect schistosome-based bladder cancer: is the association sufficient for epidemiological use?","volume":"104","author":"Shiff","year":"2010","journal-title":"Trans R Soc Trop Med Hyg"},{"issue":"5","key":"2019061111094879700_try144C6","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/j.trstmh.2006.08.008","article-title":"Prevalence of urinary schistosomiasis and HIV in females living in a rural community of Zimbabwe: does age matter?","volume":"101","author":"Ndhlovu","year":"2007","journal-title":"Trans R Soc Trop Med Hyg"},{"issue":"4","key":"2019061111094879700_try144C7","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.ijpara.2003.12.003","article-title":"Sex- and stage-related sensitivity of Schistosoma mansoni to in vivo and in vitro praziquantel treatment","volume":"34","author":"Pica-Mattoccia","year":"2004","journal-title":"Int J Parasitol"},{"issue":"2","key":"2019061111094879700_try144C8","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.exppara.2011.06.015","article-title":"The use of pentoxifylline as adjuvant therapy with praziquantel down regulates profibrogenic cytokines, collagen deposition and oxidative stress in experimental schistosomiasis mansoni","volume":"129","author":"El-Lakkany","year":"2011","journal-title":"Exp Parasitol"},{"issue":"9","key":"2019061111094879700_try144C9","doi-asserted-by":"crossref","first-page":"w506","DOI":"10.1093\/cid\/ciw506","article-title":"Reduced efficacy of praziquantel against Schistosoma mansoni is associated with multiple rounds of mass drug administration","volume":"63","author":"Crellen","year":"2016","journal-title":"Clin Infect Dis"},{"issue":"1","key":"2019061111094879700_try144C10","doi-asserted-by":"crossref","first-page":"E15","DOI":"10.3390\/ph11010015","article-title":"Drug repurposing for schistosomiasis: combinations of drugs or biomolecules","volume":"11","author":"Gouveia","year":"2018","journal-title":"Pharmaceuticals (Basel)"},{"key":"2019061111094879700_try144C11","author":"World Health Organization","year":"2012"},{"issue":"Pt A","key":"2019061111094879700_try144C12","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.actatropica.2014.09.018","article-title":"Spotlight on the in vitro effect of artemisinin-naphthoquine phosphate on Schistosoma mansoni and its snail host Biomphalaria alexandrina","volume":"141","author":"El-Beshbishi","year":"2015","journal-title":"Acta Trop"},{"key":"2019061111094879700_try144C13","article-title":"Efficacy of artemisinin-naphthoquine phosphate against Schistosoma haematobium adult flukes: dose-effect relationship and tegumental alterations","author":"El-Beshbishi","year":"2018","journal-title":"J Helminthol"},{"issue":"4","key":"2019061111094879700_try144C14","doi-asserted-by":"crossref","first-page":"483","DOI":"10.4269\/ajtmh.1967.16.483","article-title":"An improved perfusion technique for recovering adult schistosomes from laboratory animals","volume":"16","author":"Duvall","year":"1967","journal-title":"Am J Trop Med Hyg"},{"issue":"7","key":"2019061111094879700_try144C15","doi-asserted-by":"crossref","first-page":"e267","DOI":"10.1371\/journal.pntd.0000267","article-title":"The NIH-NIAID schistosomiasis resource center","volume":"2","author":"Lewis","year":"2008","journal-title":"PLoS Negl Trop Dis"},{"issue":"Suppl 1","key":"2019061111094879700_try144C16","doi-asserted-by":"crossref","first-page":"S53","DOI":"10.1517\/17460441.2.S1.S53","article-title":"Schistosomes: challenges in compound screening","volume":"2","author":"Ramirez","year":"2007","journal-title":"Expert Opin Drug Discov"},{"issue":"1\u20132","key":"2019061111094879700_try144C17","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.vetpar.2004.12.017","article-title":"The effect of free and polyethylene glycol-liposome-entrapped albendazole on larval mobility and number in Toxocara canis infected mice","volume":"129","author":"Horiuchi","year":"2005","journal-title":"Vet Parasitol"},{"issue":"6","key":"2019061111094879700_try144C18","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1080\/13880200701389425","article-title":"Large-scale in vitro screening of Egyptian native and cultivated plants for schistosomicidal activity","volume":"45","author":"Yousif","year":"2007","journal-title":"Pharm Biol"},{"issue":"4","key":"2019061111094879700_try144C19","first-page":"567","article-title":"Molluscicide screening and evaluation","volume":"33","author":"World Health Organization","year":"1965","journal-title":"Bull World Health Org"},{"issue":"10","key":"2019061111094879700_try144C20","doi-asserted-by":"crossref","first-page":"e1348","DOI":"10.1371\/journal.pntd.0001348","article-title":"Genetic manipulation of Schistosoma haematobium, the neglected schistosome","volume":"5","author":"Rinaldi","year":"2011","journal-title":"PLoS Negl Trop Dis"},{"key":"2019061111094879700_try144C21","year":"2001"},{"issue":"1","key":"2019061111094879700_try144C22","first-page":"20","article-title":"Hundred and one cases of Plasmodium falciparum treated with naphthoquine phosphate","volume":"17","author":"Pang","year":"1999","journal-title":"Chin J Parasit Dis"},{"key":"2019061111094879700_try144C23","volume-title":"Global technical strategy for malaria 2016\u20132030","author":"World Health Organization","year":"2015"},{"key":"2019061111094879700_try144C24","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1186\/1475-2875-11-153","article-title":"Efficacy and safety of artemisinin-naphthoquine versus dihydroartemisinin-piperaquine in adult patients with uncomplicated malaria: a multi-centre study in Indonesia","volume":"11","author":"Tjitera","year":"2012","journal-title":"Malar J"},{"key":"2019061111094879700_try144C25","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1186\/s12936-015-0919-5","article-title":"A systematic review of the efficacy of a single dose artemisinin\u2013naphthoquine in treating uncomplicated malaria","volume":"14","author":"Naing","year":"2015","journal-title":"Malar J"},{"issue":"11","key":"2019061111094879700_try144C26","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1177\/0091270009356296","article-title":"Single-dose safety, pharmacokinetics, and food effects studies of compound naphthoquine phosphate tablets in healthy volunteers","volume":"50","author":"Qu","year":"2010","journal-title":"J Clin Pharmacol"},{"issue":"27","key":"2019061111094879700_try144C27","doi-asserted-by":"crossref","first-page":"6010","DOI":"10.1016\/j.febslet.2005.09.035","article-title":"Structural and morphological characterization of haemozoin produced by Schistosoma mansoni and Rhodnius prolixus","volume":"579","author":"Oliveira","year":"2005","journal-title":"FEBS Lett"},{"issue":"2","key":"2019061111094879700_try144C28","doi-asserted-by":"crossref","first-page":"e1474","DOI":"10.1371\/journal.pntd.0001474","article-title":"Antischistosomal activity of trioxaquines: In vivo efficacy and mechanism of action on Schistosoma mansoni","volume":"6","author":"Portela","year":"2012","journal-title":"PLoS Negl Trop Dis"},{"issue":"5","key":"2019061111094879700_try144C29","doi-asserted-by":"crossref","first-page":"2465","DOI":"10.1128\/AAC.06248-11","article-title":"Artemisinin-naphthoquine combination therapy for uncomplicated pediatric malaria: a tolerability, safety, and preliminary efficacy study","volume":"56","author":"Benjamin","year":"2012","journal-title":"Antimicrob Agents Chemother"},{"issue":"1","key":"2019061111094879700_try144C30","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S0035-9203(01)90336-0","article-title":"Artemether administered together with haemin damages schistosomes in vitro","volume":"95","author":"Xiao","year":"2001","journal-title":"Trans R Soc Trop Med Hyg"},{"issue":"7","key":"2019061111094879700_try144C31","doi-asserted-by":"crossref","first-page":"e477","DOI":"10.1371\/journal.pntd.0000477","article-title":"Interference with haemozoin formation represents an important mechanism of schistosomicidal action of antimalarial quinoline methanols","volume":"3","author":"Corr\u00eaa Soares","year":"2009","journal-title":"PLoS Negl Trop Dis"},{"key":"2019061111094879700_try144C32","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1186\/1756-3305-4-73","article-title":"Bioactivity of miltefosine against aquatic stages of Schistosoma mansoni and Schistosoma haematobium and their snail hosts, supported by scanning electron microscopy","volume":"4","author":"Eissa","year":"2011","journal-title":"Parasit Vectors"},{"issue":"8","key":"2019061111094879700_try144C33","doi-asserted-by":"crossref","first-page":"3383","DOI":"10.1128\/AAC.00173-10","article-title":"In vitro and in vivo activities of arachidonic acid against Schistosoma mansoni and Schistosoma haematobium","volume":"54","author":"El Ridi","year":"2010","journal-title":"Antimicrob Agents Chemother"},{"issue":"4","key":"2019061111094879700_try144C34","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1006\/expr.1995.1152","article-title":"Schistosoma: rate of glucose import is altered by acetylcholine interaction with tegumental acetylcholine receptors and acetyl cholinesterase","volume":"81","author":"Camacho","year":"1995","journal-title":"Exp Parasitol"},{"issue":"7","key":"2019061111094879700_try144C35","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1007\/s004360050320","article-title":"Enzymatic basis for the lack of oxamniquine activity in Schistosoma haematobium infections","volume":"83","author":"Pica-Mattoccia","year":"1997","journal-title":"Parasitol Res"},{"issue":"2","key":"2019061111094879700_try144C36","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1017\/S0031182000053920","article-title":"Schistosoma mansoni: structural damage and tegumental repair after in vivo treatment with praziquantel","volume":"94","author":"Shaw","year":"1987","journal-title":"Parasitology"},{"key":"2019061111094879700_try144C37"}],"container-title":["Transactions of The Royal Society of Tropical Medicine and Hygiene"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/trstmh\/article-pdf\/113\/6\/320\/28793049\/try144.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,11]],"date-time":"2019-06-11T16:18:08Z","timestamp":1560269888000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/trstmh\/article\/113\/6\/320\/5298191"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,21]]},"references-count":37,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2019,1,21]]},"published-print":{"date-parts":[[2019,6,1]]}},"URL":"https:\/\/doi.org\/10.1093\/trstmh\/try144","relation":{},"ISSN":["0035-9203","1878-3503"],"issn-type":[{"value":"0035-9203","type":"print"},{"value":"1878-3503","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2019,6]]},"published":{"date-parts":[[2019,1,21]]}}}