{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T04:58:34Z","timestamp":1788325114546,"version":"build-2803163510"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2019,4,29]],"date-time":"2019-04-29T00:00:00Z","timestamp":1556496000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Odense University Hospital Free Research Fund"},{"name":"Region of Southern Denmark Research Fund"},{"name":"Aase and Ejner Danielsen Fund and the A. P. M\u00f8ller Foundation for the Advancement of Medical Science"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,9,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Gastrointestinal (GI) parasitic infections cause significant morbidity and mortality in tropical and subtropical countries. We aimed to investigate the prevalence of GI parasitic infections in children from Bissau, Guinea-Bissau and to identify the possible risk factors for these infections.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We performed an observational study on two comparable cohorts of children 2\u201315 y of age: one study covering health care\u2013seeking children (n=748) and one study covering children from the background population (n=851). A total of 1274 faecal samples from the two cohorts were investigated for parasites by microscopy and the risk factors for infection were identified by logistic regression.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Intestinal parasitic infections were found in 54.8% of health care\u2013seeking children and 55.5% of children from the background population. Helminth infections were more common among health care\u2013seeking children and were mainly due to hookworms. Pathogenic protozoa included Entamoeba histolytica\/dispar and Giardia lamblia. The risk factors for infections included increasing age, household crowding and poor sanitation and water supply.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>We found a high prevalence of intestinal parasites among both health care\u2013seeking children and children from the background population. Compared with previous studies, we found a decreasing prevalence of intestinal helminths. This study further identifies potential risk factors for infections, including inadequate sanitation and water supply.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/trstmh\/trz032","type":"journal-article","created":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T23:16:04Z","timestamp":1554160564000},"page":"545-554","source":"Crossref","is-referenced-by-count":12,"title":["Prevalence and potential risk factors for gastrointestinal parasitic infections in children in urban Bissau, Guinea-Bissau"],"prefix":"10.1093","volume":"113","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8127-6815","authenticated-orcid":false,"given":"Sebastian","family":"von Huth","sequence":"first","affiliation":[{"name":"Cancer and Inflammation Research, Department of Molecular Medicine, University of Southern Denmark, J. B. Winslows, Odense C, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Poul-Erik","family":"Kofoed","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Kolding Hospital, Skovvangen 2-8, Kolding, Denmark"},{"name":"Bandim Health Project, INDEPTH Network, Apartado, Bissau, Guinea-Bissau"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uffe","family":"Holmskov","sequence":"additional","affiliation":[{"name":"Cancer and Inflammation Research, Department of Molecular Medicine, University of Southern Denmark, J. B. 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