{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T06:21:00Z","timestamp":1771654860194,"version":"3.50.1"},"reference-count":48,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2022,6,21]],"date-time":"2022-06-21T00:00:00Z","timestamp":1655769600000},"content-version":"vor","delay-in-days":171,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"the Planning Funds for Science and Technology of Guangdong Province","award":["2020A1515011112"],"award-info":[{"award-number":["2020A1515011112"]}]},{"name":"the Guangdong Province Key Field Research and Development Program","award":["2020B111118001 and 2020B1111320001"],"award-info":[{"award-number":["2020B111118001 and 2020B1111320001"]}]},{"name":"the Scientific and Technological Research Projects of Foshan","award":["2020001000151"],"award-info":[{"award-number":["2020001000151"]}]},{"name":"The Scientific and Technological Research Projects of Guangzhou","award":["202103000008"],"award-info":[{"award-number":["202103000008"]}]},{"name":"the Guangzhou Science Technology and Innovation Commission","award":["201804020080"],"award-info":[{"award-number":["201804020080"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,7,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Coronavirus infections cause diseases that range from mild to severe in mammals and birds. In this study, we detected coronavirus infections in 748 farmed wild animals of 23 species in Guangdong, southern China, by RT-PCR and metagenomic analysis. We identified four coronaviruses in these wild animals and analysed their evolutionary origins. Coronaviruses detected in Rhizomys sinensis were genetically grouped into canine and rodent coronaviruses, which were likely recombinants of canine and rodent coronaviruses. The coronavirus found in Phasianus colchicus was a recombinant pheasant coronavirus of turkey coronavirus and infectious bronchitis virus. The coronavirus in Paguma larvata had a high nucleotide identity (94.6\u201398.5\u2009per cent) with a coronavirus of bottlenose dolphin (Tursiops truncates). These findings suggested that the wildlife coronaviruses may have experienced homologous recombination and\/or crossed the species barrier, likely resulting in the emergence of new coronaviruses. It is necessary to reduce human\u2013animal interactions by prohibiting the eating and raising of wild animals, which may contribute to preventing the emergence of the next coronavirus pandemic.<\/jats:p>","DOI":"10.1093\/ve\/veac049","type":"journal-article","created":{"date-parts":[[2022,6,21]],"date-time":"2022-06-21T13:55:08Z","timestamp":1655819708000},"source":"Crossref","is-referenced-by-count":10,"title":["Identification of coronaviruses in farmed wild animals reveals their evolutionary origins in Guangdong, southern China"],"prefix":"10.1093","volume":"8","author":[{"given":"Xiaohu","family":"Wang","sequence":"first","affiliation":[{"name":"Key Laboratory of Livestock Disease Prevention of Guangdong Province, Scientific Observation and Key Laboratory for prevention and control of Avian Influenza and Other Major Poultry Diseases, Ministry of Agriculture and Rural Affairs, Institute of Animal Health, Guangdong Academy of Agricultural Sciences , Baishigang, Wushan Street, Tianhe 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