{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T22:22:53Z","timestamp":1767046973328,"version":"3.46.0"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T00:00:00Z","timestamp":1757376000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"European Union Horizon Europe","award":["101056883"],"award-info":[{"award-number":["101056883"]}]},{"DOI":"10.13039\/501100002341","name":"Academy of Finland","doi-asserted-by":"publisher","award":["310372","310371"],"award-info":[{"award-number":["310372","310371"]}],"id":[{"id":"10.13039\/501100002341","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,12,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The role of residential dampness and molds in the occurrence of respiratory tract infections is not well understood. We assessed the relations between cumulative lifetime and time-specific dampness and mold exposures and the occurrence of upper and lower respiratory tract infections (URTI and LRTI) from pregnancy to 27\u00a0years of age in the prospective population-based Espoo Cohort Study (n\u00a0=\u00a02568). We assessed 3 questionnaire-based reports of residential exposure to water damage, moisture on the surfaces, visible mold and mold odor, and incidence rates of URTI and LRTI when children were 1-6, 7-13, and 21-27\u00a0years. We estimated adjusted incidence rate differences (aIRD) and ratios (aIRR) with their 95% CI. According to all the data combined from 3 follow-ups, home exposure to dampness and mold increased the risk of URTIs (aIRR 1.15 [95% CI, 1.10-1.21]) and LRTIs (aIRR 1.47 [95% CI, 1.21-1.79). An exposure-response pattern was observed, with each additional exposure time point particularly associated with an increased risk of LRTIs due to water damage (aIRR 2.13; 1.32-3.44) and mold odor (aIRR 2.04; 1.22-3.43). The occurrence of respiratory tract infections was associated with both presence and duration of residential dampness and mold exposure.<\/jats:p>","DOI":"10.1093\/aje\/kwaf200","type":"journal-article","created":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T09:15:16Z","timestamp":1757409316000},"page":"3492-3500","source":"Crossref","is-referenced-by-count":1,"title":["Home dampness and molds and occurrence of respiratory tract infections in the first 27\u00a0years of life: the Espoo Cohort Study"],"prefix":"10.1093","volume":"194","author":[{"given":"Joona","family":"Maaranen","sequence":"first","affiliation":[{"name":"Center for Environmental and Respiratory Health Research (CERH), Research Unit of Population Health, University of Oulu , Oulu ,","place":["Finland"]}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2558-1780","authenticated-orcid":false,"given":"Timo T","family":"Hugg","sequence":"additional","affiliation":[{"name":"Center for Environmental and Respiratory Health Research (CERH), Research Unit of Population Health, University of Oulu , Oulu ,","place":["Finland"]}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5762-7814","authenticated-orcid":false,"given":"In\u00eas","family":"Paci\u00eancia","sequence":"additional","affiliation":[{"name":"Center for Environmental and Respiratory Health Research (CERH), Research Unit of Population Health, University of Oulu , Oulu ,","place":["Finland"]}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1373-7784","authenticated-orcid":false,"given":"Maritta S","family":"Jaakkola","sequence":"additional","affiliation":[{"name":"Center for Environmental and Respiratory Health Research (CERH), Research Unit of Population Health, University of Oulu , Oulu ,","place":["Finland"]}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4168-4683","authenticated-orcid":false,"given":"Jouni J K","family":"Jaakkola","sequence":"additional","affiliation":[{"name":"Center for Environmental and Respiratory Health Research (CERH), Research Unit of Population Health, University of Oulu , Oulu ,","place":["Finland"]},{"name":"Finnish Meteorological Institute , Helsinki ,","place":["Finland"]}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4845-076X","authenticated-orcid":false,"given":"Aino K","family":"Rantala","sequence":"additional","affiliation":[{"name":"Center for Environmental and Respiratory Health Research (CERH), Research Unit of Population Health, University of Oulu , Oulu ,","place":["Finland"]}]}],"member":"286","published-online":{"date-parts":[[2025,9,9]]},"reference":[{"issue":"10159","key":"2025120218125170700_ref1","doi-asserted-by":"publisher","first-page":"1789","DOI":"10.1016\/S0140-6736(18)32279-7","article-title":"Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990\u20132017: a systematic analysis for the Global Burden of Disease Study 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