{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T16:52:30Z","timestamp":1774025550719,"version":"3.50.1"},"reference-count":176,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2018,5,23]],"date-time":"2018-05-23T00:00:00Z","timestamp":1527033600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/about_us\/legal\/notices"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,8,1]]},"DOI":"10.1093\/cvr\/cvy122","type":"journal-article","created":{"date-parts":[[2018,5,16]],"date-time":"2018-05-16T23:12:05Z","timestamp":1526512325000},"page":"1287-1303","source":"Crossref","is-referenced-by-count":93,"title":["Complex roads from genotype to phenotype in dilated cardiomyopathy: scientific update from the Working Group of Myocardial Function of the European Society of Cardiology"],"prefix":"10.1093","volume":"114","author":[{"given":"Antoine","family":"Bondue","sequence":"first","affiliation":[{"name":"Department of Cardiology, CUB H\u00f4pital Erasme, Universit\u00e9 Libre de Bruxelles, Brussels, Belgium"}]},{"given":"Eloisa","family":"Arbustini","sequence":"additional","affiliation":[{"name":"Centre for Inherited Cardiovascular Diseases, IRCCS Foundation, University Hospital Policlinico San Matteo, Pavia, Italy"}]},{"given":"Anna","family":"Bianco","sequence":"additional","affiliation":[{"name":"Department of Translational Medical Sciences, Federico II University, Naples, Italy"},{"name":"Department of Cardiology, Maastricht University Medical Center & CARIM, Maastricht University, Maastricht, The Netherlands"}]},{"given":"Michele","family":"Ciccarelli","sequence":"additional","affiliation":[{"name":"School of Medicine, Surgery and Dentistry, University of Salerno, Salerno, Italy"}]},{"given":"Dana","family":"Dawson","sequence":"additional","affiliation":[{"name":"School of Medicine and Dentistry, University of Aberdeen, Aberdeen, UK"}]},{"given":"Matteo","family":"De Rosa","sequence":"additional","affiliation":[{"name":"School of Medicine, Surgery and Dentistry, University of Salerno, Salerno, Italy"}]},{"given":"Nazha","family":"Hamdani","sequence":"additional","affiliation":[{"name":"Department of Systems Physiology, Ruhr University Bochum, Bochum, Germany"}]},{"given":"Denise","family":"Hilfiker-Kleiner","sequence":"additional","affiliation":[{"name":"Molecular Cardiology, Department of Cardiology and Angiology, Hannover Medical School, Hannover, Germany"}]},{"given":"Benjamin","family":"Meder","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Heidelberg University, Heidelberg, Germany"},{"name":"Department of Genetics, Stanford University School of Medicine, Genome Technology Center, Palo Alto, CA, USA"}]},{"given":"Adelino F","family":"Leite-Moreira","sequence":"additional","affiliation":[{"name":"Cardiovascular R&D Unit, Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto, Portugal"},{"name":"Department of Cardiothoracic Surgery, Hospital of S. Jo\u00e3o, Porto, Portugal"}]},{"given":"Thomas","family":"Thum","sequence":"additional","affiliation":[{"name":"Institute of Molecular and Translational Therapeutic Strategies, Hannover Medical School, Hannover, Germany"}]},{"given":"Carlo G","family":"Tocchetti","sequence":"additional","affiliation":[{"name":"Department of Translational Medical Sciences, Federico II University, Naples, Italy"}]},{"given":"Gilda","family":"Varricchi","sequence":"additional","affiliation":[{"name":"Department of Translational Medical Sciences, Federico II University, Naples, Italy"}]},{"given":"Jolanda","family":"Van der Velden","sequence":"additional","affiliation":[{"name":"Department of Physiology, VU University Medical Centre, Amsterdam Cardiovascular Sciences, Amsterdam, The Netherlands"},{"name":"Netherlands Heart Institute, Utrecht, The Netherlands"}]},{"given":"Roddy","family":"Walsh","sequence":"additional","affiliation":[{"name":"Cardiovascular Research Center, Royal Brompton and Harefield NHS Foundation Trust and Imperial College London, London, UK"}]},{"given":"Stephane","family":"Heymans","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Maastricht University Medical Center & CARIM, Maastricht University, Maastricht, The Netherlands"},{"name":"Netherlands Heart Institute, Utrecht, The Netherlands"},{"name":"Department of Cardiovascular Sciences, Leuven University, Leuven, Belgium"}]}],"member":"286","published-online":{"date-parts":[[2018,5,23]]},"reference":[{"key":"key\n\t\t\t\t20180720091914_cvy122-B1","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1161\/CIRCRESAHA.116.309396","article-title":"Dilated cardiomyopathy: genetic determinants and mechanisms","volume":"121","author":"McNally","year":"2017","journal-title":"Circ Res"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B2","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1038\/nrcardio.2013.105","article-title":"Dilated cardiomyopathy: the complexity of a diverse genetic architecture","volume":"10","author":"Hershberger","year":"2013","journal-title":"Nat Rev Cardiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B3","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1136\/hrt.54.2.153","article-title":"Prevalence of overt dilated cardiomyopathy in two regions of England","volume":"54","author":"Williams","year":"1985","journal-title":"Br Heart J"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B4","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1161\/01.CIR.80.3.564","article-title":"Epidemiology of idiopathic dilated and hypertrophic cardiomyopathy. A population-based study in Olmsted County, Minnesota, 1975-1984","volume":"80","author":"Codd","year":"1989","journal-title":"Circulation"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B5","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1016\/j.amjcard.2011.06.022","article-title":"Review and metaanalysis of the frequency of familial dilated cardiomyopathy","volume":"108","author":"Petretta","year":"2011","journal-title":"Am J Cardiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B6","article-title":"The Cardiomyopathy Registry of the EURObservational Research Programme of the European Society of Cardiology: baseline data and contemporary management of adult patients with cardiomyopathies","volume":"29","author":"Charron","year":"2018","journal-title":"Eur Heart J"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B7","doi-asserted-by":"crossref","first-page":"1850","DOI":"10.1093\/eurheartj\/ehv727","article-title":"Proposal for a revised definition of dilated cardiomyopathy, hypokinetic non-dilated cardiomyopathy, and its implications for clinical practice: a position statement of the ESC working group on myocardial and pericardial diseases","volume":"37","author":"Pinto","year":"2016","journal-title":"Eur Heart J"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B8","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1161\/CIRCGENETICS.115.001157","article-title":"Complexities of genetic testing in familial dilated cardiomyopathy","volume":"9","author":"Wolf","year":"2016","journal-title":"Circ Cardiovasc Genet"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B9","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1038\/nrcardio.2013.108","article-title":"Genetic testing for inherited cardiac disease","volume":"10","author":"Wilde","year":"2013","journal-title":"Nat Rev Cardiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B10","doi-asserted-by":"crossref","first-page":"2871","DOI":"10.1016\/j.jacc.2016.08.079","article-title":"Clinical and mechanistic insights into the genetics of cardiomyopathy","volume":"68","author":"Burke","year":"2016","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B11","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1161\/CIRCRESAHA.116.309386","article-title":"Pediatric cardiomyopathies","volume":"121","author":"Lee","year":"2017","journal-title":"Circ Res"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B12","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1038\/gim.2016.90","article-title":"Reassessment of Mendelian gene pathogenicity using 7,855 cardiomyopathy cases and 60,706 reference samples","volume":"19","author":"Walsh","year":"2016","journal-title":"Genet Med"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B13","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1056\/NEJMoa1110186","article-title":"Truncations of titin causing dilated cardiomyopathy","volume":"366","author":"Herman","year":"2012","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B14","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1038\/ng815","article-title":"Mutations of TTN, encoding the giant muscle filament titin, cause familial dilated cardiomyopathy","volume":"30","author":"Gerull","year":"2002","journal-title":"Nat Genet"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B15","article-title":"Titin cardiomyopathy leads to altered mitochondrial energetics, increased fibrosis and long-term life-threatening arrhythmias","volume":"10","author":"Verdonschot","year":"2018","journal-title":"Eur Heart J"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B16","doi-asserted-by":"crossref","first-page":"2264","DOI":"10.1016\/j.jacc.2017.08.063","article-title":"Phenotype and clinical outcomes of titin cardiomyopathy","volume":"70","author":"Tayal","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B17","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1111\/j.1752-8062.2010.00198.x","article-title":"Identification of novel mutations in RBM20 in patients with dilated cardiomyopathy","volume":"3","author":"Li","year":"2010","journal-title":"Clin Transl Sci"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B18","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/j.hrthm.2011.10.016","article-title":"Genetic variation in the alternative splicing regulator RBM20 is associated with dilated cardiomyopathy","volume":"9","author":"Refaat","year":"2012","journal-title":"Heart Rhythm"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B19","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1016\/S0735-1097(02)02954-6","article-title":"Natural history of dilated cardiomyopathy due to lamin A\/C gene mutations","volume":"41","author":"Taylor","year":"2003","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B20","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1136\/jmg.40.8.560","article-title":"Expanding the phenotype of LMNA mutations in dilated cardiomyopathy and functional consequences of these mutations","volume":"40","author":"S\u00e9billon","year":"2003","journal-title":"J Med Genet"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B21","first-page":"376","article-title":"Lamin A\/C cardiomyopathy: young onset, high penetrance, and frequent need for heart transplantation","volume":"15","author":"Hasselberg","year":"2017","journal-title":"Eur Heart J"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B22","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1007\/s00109-004-0589-1","article-title":"Meta-analysis of clinical characteristics of 299 carriers of LMNA gene mutations: do lamin A\/C mutations portend a high risk of sudden death?","volume":"83","author":"van Berlo","year":"2005","journal-title":"J Mol Med"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B23","doi-asserted-by":"crossref","first-page":"2440","DOI":"10.1016\/j.jacc.2016.09.927","article-title":"Truncating FLNC mutations are associated with high-risk dilated and arrhythmogenic cardiomyopathies","volume":"68","author":"Ortiz-Genga","year":"2016","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B24","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/j.ejheart.2005.11.003","article-title":"Desmin accumulation restrictive cardiomyopathy and atrioventricular block associated with desmin gene defects","volume":"8","author":"Arbustini","year":"2006","journal-title":"Eur J Heart Fail"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B25","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.ceb.2015.01.004","article-title":"Desmin related disease: a matter of cell survival failure","volume":"32","author":"Capetanaki","year":"2015","journal-title":"Curr Opin Cell Biol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B26","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.1073\/pnas.0510519103","article-title":"A mutation in the human phospholamban gene, deleting arginine 14, results in lethal, hereditary cardiomyopathy","volume":"103","author":"Haghighi","year":"2006","journal-title":"Proc Natl Acad Sci USA"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B27","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1093\/eurjhf\/hfs119","article-title":"Phospholamban R14del mutation in patients diagnosed with dilated cardiomyopathy or arrhythmogenic right ventricular cardiomyopathy: evidence supporting the concept of arrhythmogenic cardiomyopathy","volume":"14","author":"van der Zwaag","year":"2012","journal-title":"Eur J Heart Fail"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B28","doi-asserted-by":"crossref","first-page":"1410","DOI":"10.1126\/science.1081578","article-title":"Dilated cardiomyopathy and heart failure caused by a mutation in phospholamban","volume":"299","author":"Schmitt","year":"2003","journal-title":"Science"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B29","doi-asserted-by":"crossref","first-page":"2160","DOI":"10.1016\/j.jacc.2010.09.084","article-title":"SCN5A mutations associate with arrhythmic dilated cardiomyopathy and commonly localize to the voltage-sensing mechanism","volume":"57","author":"McNair","year":"2011","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B30","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1007\/s00392-011-0289-0","article-title":"Sudden cardiac death in a patient with lamin A\/C mutation in the absence of dilated cardiomyopathy or conduction disease","volume":"100","author":"Ehlermann","year":"2011","journal-title":"Clin Res Cardiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B31","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1093\/europace\/eut291","article-title":"Risk prediction of ventricular arrhythmias and myocardial function in Lamin A\/C mutation positive subjects","volume":"16","author":"Hasselberg","year":"2014","journal-title":"Europace"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B32","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1093\/europace\/eur245","article-title":"HRS\/EHRA expert consensus statement on the state of genetic testing for the channelopathies and cardiomyopathies this document was developed as a partnership between the Heart Rhythm Society (HRS) and the European Heart Rhythm Association (EHRA)","volume":"13","author":"Ackerman","year":"2011","journal-title":"Europace"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B33","first-page":"1601","article-title":"2015 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: the task force for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death of the European Society of Cardiology (ESC) Endorsed by: association for European Paediatric and Congenital Cardiology (AEPC)","volume":"17","author":"Priori","year":"2015","journal-title":"Europace"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B34","doi-asserted-by":"crossref","first-page":"1641","DOI":"10.1016\/j.jacc.2011.01.015","article-title":"Update 2011: clinical and genetic issues in familial dilated cardiomyopathy","volume":"57","author":"Hershberger","year":"2011","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B35","doi-asserted-by":"crossref","first-page":"1799","DOI":"10.1016\/j.bbamcr.2016.02.014","article-title":"The role of mutations in the SCN5A gene in cardiomyopathies","volume":"1863","author":"Zaklyazminskaya","year":"2016","journal-title":"Biochim Biophys Acta"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B36","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1097\/GIM.0b013e3181f2481f","article-title":"Clinical and genetic issues in dilated cardiomyopathy: a review for genetics professionals","volume":"12","author":"Hershberger","year":"2010","journal-title":"Genet Med"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B37","doi-asserted-by":"crossref","first-page":"20.","DOI":"10.1186\/s13073-017-0410-8","article-title":"Genetics and genomics of dilated cardiomyopathy and systolic heart failure","volume":"9","author":"Tayal","year":"2017","journal-title":"Genome Med"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B38","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1093\/eurheartj\/ehv122","article-title":"The current role of next-generation DNA sequencing in routine care of patients with hereditary cardiovascular conditions: a viewpoint paper of the European Society of Cardiology working group on myocardial and pericardial diseases and members of the European Society of Human Genetics","volume":"36","author":"Mogensen","year":"2015","journal-title":"Eur Heart J"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B39","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1002\/ejhf.1103","article-title":"Evolving concepts in dilated cardiomyopathy","volume":"20","author":"Merlo","year":"2018","journal-title":"Eur J Heart Fail"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B40","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.abb.2016.12.007","article-title":"Altered myocyte contractility and calcium homeostasis in alpha-myosin heavy chain point mutations linked to familial dilated cardiomyopathy","volume":"615","author":"Klos","year":"2017","journal-title":"Arch Biochem Biophys"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B41","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1161\/CIRCULATIONAHA.104.507699","article-title":"Alpha-myosin heavy chain: a sarcomeric gene associated with dilated and hypertrophic phenotypes of cardiomyopathy","volume":"112","author":"Carniel","year":"2005","journal-title":"Circulation"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B42","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1038\/ejhg.2009.34","article-title":"The role of sarcomere gene mutations in patients with idiopathic dilated cardiomyopathy","volume":"17","author":"M\u00f8ller","year":"2009","journal-title":"Eur J Hum Genet"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B43","doi-asserted-by":"crossref","first-page":"2419","DOI":"10.1016\/j.jacc.2007.02.061","article-title":"Prevalence, clinical significance, and genetic basis of hypertrophic cardiomyopathy with restrictive phenotype","volume":"49","author":"Kubo","year":"2007","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B44","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1016\/j.cell.2016.04.002","article-title":"A tension-based model distinguishes hypertrophic versus dilated cardiomyopathy","volume":"165","author":"Davis","year":"2016","journal-title":"Cell"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B45","doi-asserted-by":"crossref","first-page":"3403","DOI":"10.1021\/acs.biochem.7b00266","article-title":"Clinically divergent mutation effects on the structure and function of the human cardiac tropomyosin overlap","volume":"56","author":"McConnell","year":"2017","journal-title":"Biochemistry"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B46","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1161\/CIRCULATIONAHA.116.024482","article-title":"Long-term biased \u03b2-arrestin signaling improves cardiac structure and function in dilated cardiomyopathy","volume":"135","author":"Ryba","year":"2017","journal-title":"Circulation"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B47","doi-asserted-by":"crossref","first-page":"4677","DOI":"10.1113\/JP274145","article-title":"Genotype-specific pathogenic effects in human dilated cardiomyopathy","volume":"595","author":"Bollen","year":"2017","journal-title":"J Physiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B48","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/j.jacc.2011.08.078","article-title":"Risk factors for malignant ventricular arrhythmias in lamin A\/C mutation carriers","volume":"59","author":"van Rijsingen","year":"2012","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B49","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1161\/CIRCGENETICS.110.937805","article-title":"Prevalence of desmosomal protein gene mutations in patients with dilated cardiomyopathy","volume":"3","author":"Elliott","year":"2010","journal-title":"Circ Cardiovasc Genet"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B50","doi-asserted-by":"crossref","first-page":"e002149","DOI":"10.1161\/JAHA.115.002149","article-title":"Arrhythmogenic phenotype in dilated cardiomyopathy: natural history and predictors of life-threatening arrhythmias","volume":"4","author":"Spezzacatene","year":"2015","journal-title":"J Am Heart Assoc"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B51","doi-asserted-by":"crossref","first-page":"2175","DOI":"10.1016\/j.jacc.2008.09.019","article-title":"Left-dominant arrhythmogenic cardiomyopathy","volume":"52","author":"Sen-Chowdhry","year":"2008","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B52","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1056\/NEJMra1509267","article-title":"Arrhythmogenic right ventricular cardiomyopathy","volume":"376","author":"Corrado","year":"2017","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B53","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/S1050-1738(03)00037-9","article-title":"Regulation of sarco(endo)plasmic reticulum Ca2+ adenosine triphosphatase by phospholamban and sarcolipin: implication for cardiac hypertrophy and failure","volume":"13","author":"Asahi","year":"2003","journal-title":"Trends Cardiovasc Med"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B54","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1172\/JCI84669","article-title":"Aberrant sodium influx causes cardiomyopathy and atrial fibrillation in mice","volume":"126","author":"Wan","year":"2016","journal-title":"J Clin Invest"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B55","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1093\/cvr\/cvv127","article-title":"A novel human R25C-phospholamban mutation is associated with super-inhibition of calcium cycling and ventricular arrhythmia","volume":"107","author":"Liu","year":"2015","journal-title":"Cardiovasc Res"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B56","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1038\/ncomms7955","article-title":"Correction of human phospholamban R14del mutation associated with cardiomyopathy using targeted nucleases and combination therapy","volume":"6","author":"Karakikes","year":"2015","journal-title":"Nat Commun"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B57","doi-asserted-by":"crossref","first-page":"3282","DOI":"10.1093\/eurheartj\/ehw307","article-title":"Genomic correction of familial cardiomyopathy in human engineered cardiac tissues","volume":"37","author":"Stillitano","year":"2016","journal-title":"Eur Heart J"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B58","doi-asserted-by":"crossref","first-page":"1714","DOI":"10.1016\/j.jacc.2015.08.038","article-title":"Arrhythmia-induced cardiomyopathies: mechanisms, recognition, and management","volume":"66","author":"Gopinathannair","year":"2015","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B59","doi-asserted-by":"crossref","first-page":"2208","DOI":"10.1161\/CIRCULATIONAHA.112.115592","article-title":"Pathological role of serum- and glucocorticoid-regulated kinase 1 in adverse ventricular remodeling","volume":"126","author":"Das","year":"2012","journal-title":"Circulation"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B60","doi-asserted-by":"crossref","first-page":"1446","DOI":"10.1016\/j.hrthm.2014.04.042","article-title":"Novel SCN5A mutation in amiodarone-responsive multifocal ventricular ectopy-associated cardiomyopathy","volume":"11","author":"Beckermann","year":"2014","journal-title":"Heart Rhythm"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B61","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1161\/01.RES.0000194329.41863.89","article-title":"Ca2+\/calmodulin-dependent protein kinase modulates cardiac ryanodine receptor phosphorylation and sarcoplasmic reticulum Ca2+ leak in heart failure","volume":"97","author":"Ai","year":"2005","journal-title":"Circ Res"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B62","first-page":"385","article-title":"Mitochondrial cardiomyopathy: pathophysiology, diagnosis, and management","volume":"40","author":"Meyers","year":"2013","journal-title":"Tex Heart Inst J"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B63","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/S0195-668X(02)00387-1","article-title":"Cardiomyopathy in children with mitochondrial disease;clinical course and cardiological findings","volume":"24","author":"Holmgren","year":"2003","journal-title":"Eur Heart J"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B64","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1016\/j.ijcard.2014.11.014","article-title":"Cardiac manifestations of primary mitochondrial disorders","volume":"177","author":"Finsterer","year":"2014","journal-title":"Int J Cardiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B65","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1093\/cvr\/cvx014","article-title":"Barth syndrome cardiomyopathy","volume":"113","author":"Dudek","year":"2017","journal-title":"Cardiovasc Res"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B66","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1038\/ng0496-385","article-title":"A novel X-linked gene, G4.5. is responsible for Barth syndrome","volume":"12","author":"Bione","year":"1996","journal-title":"Nat Genet"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B67","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1086\/301604","article-title":"Mutation characterization and genotype-phenotype correlation in Barth syndrome","volume":"61","author":"Johnston","year":"1997","journal-title":"Am J Hum Genet"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B68","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1016\/j.cjca.2015.08.017","article-title":"Mitochondrial diseases and cardiomyopathies","volume":"31","author":"Brunel-Guitton","year":"2015","journal-title":"Can J Cardiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B69","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1136\/jmedgenet-2013-101604","article-title":"Prevalence of rare mitochondrial DNA mutations in mitochondrial disorders","volume":"50","author":"Bannwarth","year":"2013","journal-title":"J Med Genet"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B70","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S0008-6363(00)00241-8","article-title":"Mitochondrial pathology in cardiac failure","volume":"49","author":"Marin-Garcia","year":"2001","journal-title":"Cardiovasc Res"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B71","doi-asserted-by":"crossref","first-page":"1957","DOI":"10.1161\/CIRCULATIONAHA.112.001219","article-title":"Divergent mitochondrial biogenesis responses in human cardiomyopathy","volume":"127","author":"Ahuja","year":"2013","journal-title":"Circulation"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B72","doi-asserted-by":"crossref","first-page":"2699","DOI":"10.1006\/jmcc.1997.0501","article-title":"Point mutations in mitochondrial DNA of patients with dilated cardiomyopathy","volume":"29","author":"Li","year":"1997","journal-title":"J Mol Cell Cardiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B73","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.tcb.2014.11.002","article-title":"Protecting the mitochondrial powerhouse","volume":"25","author":"Scheibye-Knudsen","year":"2015","journal-title":"Trends Cell Biol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B74","doi-asserted-by":"crossref","first-page":"aad0116","DOI":"10.1126\/science.aad0116","article-title":"Imbalanced OPA1 processing and mitochondrial fragmentation cause heart failure in mice","volume":"350","author":"Wai","year":"2015","journal-title":"Science"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B75","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1038\/nature20156","article-title":"Correcting mitochondrial fusion by manipulating mitofusin conformations","volume":"540","author":"Franco","year":"2016","journal-title":"Nature"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B76","first-page":"42","article-title":"Rays sting: the acute cellular effects of ionizing radiation exposure","volume":"14","author":"Franco","year":"2016","journal-title":"Transl Med UniSa"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B77","doi-asserted-by":"crossref","first-page":"10.","DOI":"10.1038\/s41420-018-0028-7","article-title":"GRK2 moderates the acute mitochondrial damage to ionizing radiation exposure by promoting mitochondrial fission\/fusion","volume":"4","author":"Franco","year":"2018","journal-title":"Cell Death Discov"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B78","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1016\/j.jacc.2018.01.017","article-title":"Spectrum of restrictive and infiltrative cardiomyopathies part 2 of a 2-part series","volume":"71","author":"Pereira","year":"2018","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B79","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1016\/j.jacc.2018.01.016","article-title":"Spectrum of restrictive and infiltrative cardiomyopathies part 1 of a 2-part series","volume":"71","author":"Pereira","year":"2018","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B80","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1172\/JCI200316336","article-title":"Idiopathic restrictive cardiomyopathy is part of the clinical expression of cardiac troponin I mutations","volume":"111","author":"Mogensen","year":"2003","journal-title":"J Clin Invest"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B81","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/j.ijcard.2007.07.108","article-title":"Deletion in TNNI3 gene is associated with restrictive cardiomyopathy","volume":"131","author":"Kostareva","year":"2009","journal-title":"Int J Cardiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B82","doi-asserted-by":"crossref","first-page":"e0163362","DOI":"10.1371\/journal.pone.0163362","article-title":"Genetic spectrum of idiopathic restrictive cardiomyopathy uncovered by next-generation sequencing","volume":"11","author":"Kostareva","year":"2016","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B83","doi-asserted-by":"crossref","first-page":"H2604","DOI":"10.1152\/ajpheart.91506.2007","article-title":"Impaired relaxation is the main manifestation in transgenic mice expressing a restrictive cardiomyopathy mutation, R193H, in cardiac TnI","volume":"294","author":"Du","year":"2008","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B84","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1111\/j.1399-0004.2008.01062.x","article-title":"Cardiac troponin T mutation in familial cardiomyopathy with variable remodeling and restrictive physiology","volume":"74","author":"Menon","year":"2008","journal-title":"Clin Genet"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B85","doi-asserted-by":"crossref","first-page":"2871","DOI":"10.1016\/j.jacc.2016.08.079","article-title":"Clinical and mechanistic insights into the genetics of cardiomyopathy","volume":"68","author":"Burke","year":"2016","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B86","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/HCO.0000000000000511","article-title":"Iron overload cardiomyopathy: from diagnosis to management","volume":"33","author":"D\u00edez-L\u00f3pez","year":"2018","journal-title":"Curr Opin Cardiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B87","doi-asserted-by":"crossref","first-page":"2253","DOI":"10.1161\/CIRCULATIONAHA.111.050773","article-title":"Iron overload cardiomyopathy in clinical practice","volume":"124","author":"Kremastinos","year":"2011","journal-title":"Circulation"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B88","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1038\/nature19057","article-title":"Analysis of protein-coding genetic variation in 60,706 humans","volume":"536","author":"Lek","year":"2016","journal-title":"Nature"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B89","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1161\/CIRCGENETICS.111.961805","article-title":"Evaluating pathogenicity of rare variants from dilated cardiomyopathy in the exome era","volume":"5","author":"Norton","year":"2012","journal-title":"Circ Cardiovasc Genet"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B90","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1038\/ejhg.2012.283","article-title":"New population-based exome data are questioning the pathogenicity of previously cardiomyopathy-associated genetic variants","volume":"21","author":"Andreasen","year":"2013","journal-title":"Eur J Hum Genet"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B91","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1016\/j.jacc.2009.05.038","article-title":"Mutations in ribonucleic acid binding protein gene cause familial dilated cardiomyopathy","volume":"54","author":"Brauch","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B92","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1016\/j.ajhg.2017.04.015","article-title":"Evaluating the clinical validity of gene-disease associations: an evidence-based framework developed by the clinical genome resource","volume":"100","author":"Strande","year":"2017","journal-title":"Am J Hum Genet"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B93","first-page":"3461","article-title":"Defining the genetic architecture of hypertrophic cardiomyopathy: re-evaluating the role of non-sarcomeric genes","volume":"38","author":"Walsh","year":"2017","journal-title":"Eur Heart J"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B94","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1038\/gim.2013.204","article-title":"The landscape of genetic variation in dilated cardiomyopathy as surveyed by clinical DNA sequencing","volume":"16","author":"Pugh","year":"2014","journal-title":"Genet Med"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B95","doi-asserted-by":"crossref","first-page":"270ra6","DOI":"10.1126\/scitranslmed.3010134","article-title":"Integrated allelic, transcriptional, and phenomic dissection of the cardiac effects of titin truncations in health and disease","volume":"7","author":"Roberts","year":"2015","journal-title":"Sci Transl Med"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B96","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1016\/j.cjca.2014.09.030","article-title":"Nonsense mutations in BAG3 are associated with early-onset dilated cardiomyopathy in French Canadians","volume":"30","author":"Chami","year":"2014","journal-title":"Can J Cardiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B97","doi-asserted-by":"crossref","first-page":"e0158730","DOI":"10.1371\/journal.pone.0158730","article-title":"Familial dilated cardiomyopathy caused by a novel frameshift in the BAG3 gene","volume":"11","author":"Toro","year":"2016","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B98","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1038\/gim.2015.30","article-title":"Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology","volume":"17","author":"Richards","year":"2015","journal-title":"Genet Med"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B99","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1093\/eurheartj\/eht251","article-title":"A genome-wide association study identifies 6p21 as novel risk locus for dilated cardiomyopathy","volume":"35","author":"Meder","year":"2014","journal-title":"Eur Heart J"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B100","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1093\/eurheartj\/ehr105","article-title":"A genome-wide association study identifies two loci associated with heart failure due to dilated cardiomyopathy","volume":"32","author":"Villard","year":"2011","journal-title":"Eur Heart J"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B101","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1093\/eurheartj\/ehu301","article-title":"Atlas of the clinical genetics of human dilated cardiomyopathy","volume":"36","author":"Haas","year":"2015","journal-title":"Eur Heart J"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B102","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1038\/nature09130","article-title":"Chromatin regulation by Brg1 underlies heart muscle development and disease","volume":"466","author":"Hang","year":"2010","journal-title":"Nature"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B103","doi-asserted-by":"crossref","first-page":"2135","DOI":"10.1242\/dev.132019","article-title":"Identification of a regulatory domain controlling the Nppa-Nppbgene cluster during heart development and stress","volume":"143","author":"Sergeeva","year":"2016","journal-title":"Development"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B104","article-title":"DNA hydroxymethylation controls cardiomyocyte gene expression in development and hypertrophy","volume":"7","author":"Kunderfranco","year":"2016","journal-title":"Nat Commun"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B105","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1002\/emmm.201201553","article-title":"Alterations in cardiac DNA methylation in human dilated cardiomyopathy","volume":"5","author":"Haas","year":"2013","journal-title":"EMBO Mol Med"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B106","doi-asserted-by":"crossref","first-page":"1528","DOI":"10.1161\/CIRCULATIONAHA.117.027355","article-title":"Epigenome-wide association study identifies cardiac gene patterning and a novel class of biomarkers for heart failure","volume":"136","author":"Meder","year":"2017","journal-title":"Circulation"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B107","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1161\/CIRCRESAHA.115.306721","article-title":"Adrenergic repression of the epigenetic reader MeCP2 facilitates cardiac adaptation in chronic heart failure","volume":"117","author":"Mayer","year":"2015","journal-title":"Circ Res"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B108","doi-asserted-by":"crossref","DOI":"10.1002\/ejhf.1138","article-title":"The innate immune system in chronic cardiomyopathy: a European Society of Cardiology (ESC) scientific statement from the Working Group on Myocardial Function of the ESC","volume":"20","author":"Frantz","year":"2018","journal-title":"Eur J Heart Fail"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B109","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1016\/j.jacc.2015.07.023","article-title":"Prognostic relevance of gene-environment interactions in patients with dilated cardiomyopathy: applying the MOGE(S) classification","volume":"66","author":"Hazebroek","year":"2015","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B110","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/S0735-1097(03)00648-X","article-title":"Detection of viruses in myocardial tissues by polymerase chain reaction: evidence of adenovirus as a common cause of myocarditis in children and adults","volume":"42","author":"Bowles","year":"2003","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B111","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.hfc.2005.06.011","article-title":"Viral genomic detection and outcome in myocarditis","volume":"1","author":"Bowles","year":"2005","journal-title":"Heart Fail Clin"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B112","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1016\/S0140-6736(09)62023-7","article-title":"Dilated cardiomyopathy","volume":"375","author":"Jefferies","year":"2010","journal-title":"Lancet"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B113","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2012\/129486","article-title":"Th2 regulation of viral myocarditis in mice: different roles for TLR3 versus TRIF in progression to chronic disease","volume":"2012","author":"Abston","year":"2012","journal-title":"Clin Dev Immunol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B114","doi-asserted-by":"crossref","first-page":"6710","DOI":"10.4049\/jimmunol.178.11.6710","article-title":"Cutting edge: cross-regulation by TLR4 and T cell Ig Mucin-3 determines sex differences in inflammatory heart disease","volume":"178","author":"Frisancho-Kiss","year":"2007","journal-title":"J Immunol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B115","doi-asserted-by":"crossref","first-page":"H2024","DOI":"10.1152\/ajpheart.01188.2009","article-title":"Myeloid differentiation factor-88 contributes to TLR9-mediated modulation of acute coxsackievirus B3-induced myocarditis in vivo","volume":"298","author":"Riad","year":"2010","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B116","doi-asserted-by":"crossref","first-page":"2561","DOI":"10.4049\/jimmunol.1002029","article-title":"TRIF is a critical survival factor in viral cardiomyopathy","volume":"186","author":"Riad","year":"2011","journal-title":"J Immunol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B117","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1161\/CIRCRESAHA.109.199802","article-title":"Myeloid differentiation factor-88\/Interleukin-1 signaling controls cardiac fibrosis and heart failure progression in inflammatory dilated cardiomyopathy","volume":"105","author":"Blyszczuk","year":"2009","journal-title":"Circ Res"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B118","doi-asserted-by":"crossref","first-page":"R267","DOI":"10.1152\/ajpregu.00516.2011","article-title":"TLR3 deficiency induces chronic inflammatory cardiomyopathy in resistant mice following coxsackievirus B3 infection: role for IL-4","volume":"304","author":"Abston","year":"2013","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B119","doi-asserted-by":"crossref","first-page":"23208","DOI":"10.1074\/jbc.M109.047464","article-title":"A role for toll-like receptor 3 variants in host susceptibility to enteroviral myocarditis and dilated cardiomyopathy","volume":"285","author":"Gorbea","year":"2010","journal-title":"J Biol Chem"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B120","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1586\/14779072.2015.990385","article-title":"Immunoadsorption therapy in dilated cardiomyopathy","volume":"13","author":"Felix","year":"2015","journal-title":"Expert Rev Cardiovasc Ther"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B121","doi-asserted-by":"crossref","first-page":"771","DOI":"10.4330\/wjc.v6.i8.771","article-title":"Alcoholic cardiomyopathy","volume":"6","author":"Guzzo-Merello","year":"2014","journal-title":"World J Cardiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B122","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.ejphar.2017.10.043","article-title":"Molecular mechanism of doxorubicin-induced cardiomyopathy\u2014an update","volume":"818","author":"Renu","year":"2018","journal-title":"Eur J Pharmacol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B123","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.phrs.2017.03.016","article-title":"Doxorubicin targets multiple players: a new view of an old problem","volume":"127","author":"Cappetta","year":"2018","journal-title":"Pharmacol Res"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B124","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1093\/alcalc\/agx049","article-title":"Genetic polymorphisms of alcohol metabolizing enzymes and alcohol consumption are associated with asymptomatic cardiac remodeling and subclinical systolic dysfunction in large community-dwelling Asians","volume":"52","author":"Hung","year":"2017","journal-title":"Alcohol Alcohol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B125","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1038\/ng.3374","article-title":"A coding variant in RARG confers susceptibility to anthracycline-induced cardiotoxicity in childhood cancer","volume":"47","author":"Aminkeng","year":"2015","journal-title":"Nat Genet"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B126","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1200\/JCO.2011.34.8987","article-title":"Anthracycline-related cardiomyopathy after childhood cancer: role of polymorphisms in carbonyl reductase genes\u2014a report from the Children's Oncology Group","volume":"30","author":"Blanco","year":"2012","journal-title":"J Clin Oncol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B127","doi-asserted-by":"crossref","first-page":"1422","DOI":"10.1200\/JCO.2010.34.3467","article-title":"Pharmacogenomic prediction of anthracycline-induced cardiotoxicity in children","volume":"30","author":"Visscher","year":"2012","journal-title":"J Clin Oncol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B128","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1200\/JCO.2015.63.4550","article-title":"CELF4Variant and anthracycline-related cardiomyopathy: a Children\u2019s Oncology Group genome-wide association study","volume":"34","author":"Wang","year":"2016","journal-title":"J Clin Oncol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B129","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1002\/pbc.24505","article-title":"Validation of variants in SLC28A3and UGT1A6as genetic markers predictive of anthracycline-induced cardiotoxicity in children","volume":"60","author":"Visscher","year":"2013","journal-title":"Pediatr Blood Cancer"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B130","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1200\/JCO.2013.50.3557","article-title":"Hyaluronan synthase 3 variant and anthracycline-related cardiomyopathy: a report from the Children's Oncology Group","volume":"32","author":"Wang","year":"2014","journal-title":"J Clin Oncol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B131","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1161\/01.RES.76.4.681","article-title":"Molecular basis of human cardiac troponin t isoforms expressed in the developing, adult, and failing heart","volume":"76","author":"Anderson","year":"1995","journal-title":"Circ Res"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B132","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1161\/CIRCRESAHA.117.311335","article-title":"Quaking inhibits doxorubicin-mediated cardiotoxicity through regulation of cardiac circular RNA expressionnovelty and significance","volume":"122","author":"Gupta","year":"2018","journal-title":"Circ Res"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B133","article-title":"From molecular mechanisms to clinical management of antineoplastic drug-induced cardiovascular toxicity: a translational overview","author":"Tocchetti","year":"2017","journal-title":"Antioxid Redox Signal"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B134","doi-asserted-by":"crossref","first-page":"2869","DOI":"10.1161\/01.CIR.0000146889.46519.27","article-title":"Modulation of doxorubicin-induced cardiac dysfunction in toll-like receptor-2-knockout mice","volume":"110","author":"Nozaki","year":"2004","journal-title":"Circulation"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B135","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.ejheart.2008.01.004","article-title":"Toll-like receptor-4 deficiency attenuates doxorubicin-induced cardiomyopathy in mice","volume":"10","author":"Riad","year":"2008","journal-title":"Eur J Heart Fail"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B136","doi-asserted-by":"crossref","first-page":"e40763","DOI":"10.1371\/journal.pone.0040763","article-title":"Toll-like receptor (TLR) 2 and TLR4 differentially regulate doxorubicin induced cardiomyopathy in mice","volume":"7","author":"Ma","year":"2012","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B137","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1038\/nm1622","article-title":"Toll-like receptor 4\u2013dependent contribution of the immune system to anticancer chemotherapy and radiotherapy","volume":"13","author":"Apetoh","year":"2007","journal-title":"Nat Med"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B138","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11886-017-0835-0","article-title":"Cardiovascular toxicities associated with cancer immunotherapies","volume":"19","author":"Wang","year":"2017","journal-title":"Curr Cardiol Rep"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B139","doi-asserted-by":"crossref","first-page":"1989","DOI":"10.1161\/CIRCULATIONAHA.117.029626","article-title":"Cardiac toxicity of immune checkpoint inhibitors","volume":"136","author":"Varricchi","year":"2017","journal-title":"Circulation"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B140","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1093\/eurjhf\/hfq120","article-title":"Current state of knowledge on aetiology, diagnosis, management, and therapy of peripartum cardiomyopathy: a position statement from the Heart Failure Association of the European Society of Cardiology Working Group on peripartum cardiomyopathy","volume":"12","author":"Sliwa","year":"2010","journal-title":"Eur J Heart Fail"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B141","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1093\/eurheartj\/ehv009","article-title":"Peripartum cardiomyopathy: current management and future perspectives","volume":"36","author":"Hilfiker-Kleiner","year":"2015","journal-title":"Eur Heart J"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B142","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1038\/nrcardio.2014.37","article-title":"Pathophysiology and epidemiology of peripartum cardiomyopathy","volume":"11","author":"Hilfiker-Kleiner","year":"2014","journal-title":"Nat Rev Cardiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B143","first-page":"46","article-title":"Peripartum cardiomyopathy. Insights from Haiti regarding a disease of unknown etiology","volume":"85","author":"Fett","year":"2002","journal-title":"Minn Med"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B144","doi-asserted-by":"crossref","first-page":"80.","DOI":"10.1186\/1752-1947-4-80","article-title":"Bromocriptine treatment associated with recovery from peripartum cardiomyopathy in siblings: two case reports","volume":"4","author":"Meyer","year":"2010","journal-title":"J Med Case Rep"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B145","doi-asserted-by":"crossref","first-page":"2169","DOI":"10.1161\/CIRCULATIONAHA.109.929646","article-title":"Peripartum cardiomyopathy as a part of familial dilated cardiomyopathy","volume":"121","author":"van Spaendonck-Zwarts","year":"2010","journal-title":"Circulation"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B146","doi-asserted-by":"crossref","first-page":"2165","DOI":"10.1093\/eurheartj\/ehu050","article-title":"Titin gene mutations are common in families with both peripartum cardiomyopathy and dilated cardiomyopathy","volume":"35","author":"van Spaendonck-Zwarts","year":"2014","journal-title":"Eur Heart J"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B147","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1056\/NEJMoa1505517","article-title":"Shared genetic predisposition in peripartum and dilated cardiomyopathies","volume":"374","author":"Ware","year":"2016","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B148","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.ajog.2005.01.022","article-title":"High prevalence of viral genomes and inflammation in peripartum cardiomyopathy","volume":"193","author":"B\u00fcltmann","year":"2005","journal-title":"Am J Obstet Gynecol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B149","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.ijgo.2007.01.012","article-title":"Viral infection as a possible trigger for the development of peripartum cardiomyopathy","volume":"97","author":"Fett","year":"2007","journal-title":"Int J Gynaecol Obstet"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B150","doi-asserted-by":"crossref","first-page":"2680","DOI":"10.1093\/eurheartj\/ehx428","article-title":"Bromocriptine for the treatment of peripartum cardiomyopathy: welcome on BOARD","volume":"38","author":"Arrigo","year":"2017","journal-title":"Eur Heart J"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B151","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.acvd.2011.11.007","article-title":"Diabetic cardiomyopathy: myth or reality?","volume":"105","author":"Ernande","year":"2012","journal-title":"Arch Cardiovasc Dis"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B152","doi-asserted-by":"crossref","first-page":"1628","DOI":"10.1016\/S0735-1097(00)00582-9","article-title":"Predictors of congestive heart failure in the elderly: the cardiovascular health study","volume":"35","author":"Gottdiener","year":"2000","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B153","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/0002-9149(74)90089-7","article-title":"Role of diabetes in congestive heart failure: the Framingham study","volume":"34","author":"Kannel","year":"1974","journal-title":"Am J Cardiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B154","doi-asserted-by":"crossref","first-page":"2791","DOI":"10.2337\/diacare.26.10.2791","article-title":"Diabetes and idiopathic cardiomyopathy: a nationwide case-control study","volume":"26","author":"Bertoni","year":"2003","journal-title":"Diabetes Care"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B155","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1007\/s11154-010-9131-7","article-title":"Diabetic cardiomyopathy, causes and effects","volume":"11","author":"Boudina","year":"2010","journal-title":"Rev Endocr Metab Disord"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B156","first-page":"1134.","article-title":"LMNA sequences of 60,706 unrelated individuals reveal 132 novel missense variants in A-type lamins and suggest a link between variant p.G602S and Type 2 diabetes","volume":"8","author":"Florwick","year":"2017","journal-title":"Front Genet Frontiers"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B157","doi-asserted-by":"crossref","first-page":"iii15","DOI":"10.1093\/ejechocard\/jep158","article-title":"The role of echocardiography in guiding management in dilated cardiomyopathy","volume":"10","author":"Thomas","year":"2009","journal-title":"Eur J Echocardiogr"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B158","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1016\/j.echo.2010.07.019","article-title":"Global longitudinal strain as a major predictor of cardiac events in patients with depressed left ventricular function: a multicenter study","volume":"23","author":"Mignot","year":"2010","journal-title":"J Am Soc Echocardiogr"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B159","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.jcmg.2012.09.012","article-title":"Prognostic role of CMR in patients presenting with ventricular arrhythmias","volume":"6","author":"Dawson","year":"2013","journal-title":"JACC Cardiovasc Imaging"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B160","doi-asserted-by":"crossref","first-page":"2491","DOI":"10.1161\/CIRCULATIONAHA.117.029349","article-title":"Cardiac imaging in patients with ventricular tachycardia","volume":"136","author":"Mahida","year":"2017","journal-title":"Circulation"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B161","doi-asserted-by":"crossref","first-page":"e006709.","DOI":"10.1161\/CIRCIMAGING.117.006709","article-title":"Diagnosis and prognosis in sudden cardiac arrest survivors without coronary artery disease: utility of a clinical approach using cardiac magnetic resonance imaging","volume":"10","author":"Rodrigues","year":"2017","journal-title":"Circ Cardiovasc Imaging"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B162","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1093\/eurheartj\/ehm342","article-title":"Classification of the cardiomyopathies: a position statement from the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases","volume":"29","author":"Elliott","year":"2007","journal-title":"Eur Heart J"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B163","doi-asserted-by":"crossref","first-page":"2046","DOI":"10.1016\/j.jacc.2013.08.1644","article-title":"The MOGE(S) classification for a phenotype-genotype nomenclature of cardiomyopathy: endorsed by the World Heart Federation","volume":"62","author":"Arbustini","year":"2013","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B164","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.gheart.2013.11.001","article-title":"The MOGE(S) classification for a phenotype-genotype nomenclature of cardiomyopathy: endorsed by the World Heart Federation","volume":"8","author":"Arbustini","year":"2013","journal-title":"Glob Heart"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B165","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/j.jacc.2014.05.027","article-title":"The MOGE(S) classification of cardiomyopathy for clinicians","volume":"64","author":"Arbustini","year":"2014","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B166","doi-asserted-by":"crossref","first-page":"2073","DOI":"10.1016\/j.jacc.2013.10.008","article-title":"Classification of cardiomyopathies: evolution or revolution?","volume":"62","author":"Elliott","year":"2013","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B167","first-page":"2584","article-title":"Reply: The MOGE(S) classification for a phenotype-genotype nomenclature of cardiomyopathy: more questions than answers?","volume":"8","author":"Arbustini","year":"2013","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B168","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.gheart.2015.01.001","article-title":"Clinical application of WHF-MOGE(S) classification for hypertrophic cardiomyopathy","volume":"10","author":"Agarwal","year":"2015","journal-title":"Glob Heart"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B169","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1038\/nrcardio.2013.219","article-title":"MOGE(S): a standardized classification of cardiomyopathies?","volume":"11","author":"Mayosi","year":"2014","journal-title":"Nat Rev Cardiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B170","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1016\/j.jacc.2015.06.1335","article-title":"Utilizing the MOGE(S) classification for predicting prognosis in dilated cardiomyopathy","volume":"66","author":"Dec","year":"2015","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B171","doi-asserted-by":"crossref","DOI":"10.1007\/s10741-017-9641-4","article-title":"The MOGE(S) classification for cardiomyopathies: current status and future outlook","volume":"22","author":"Westphal","year":"2017","journal-title":"Heart Fail Rev"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B172","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1016\/j.jacc.2016.05.090","article-title":"Genetic screening of anderson-fabry disease in probands referred from multispecialty clinics","volume":"68","author":"Favalli","year":"2016","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B173","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1136\/heartjnl-2017-312338","article-title":"Lamin and the heart","volume":"104","author":"Captur","year":"2018","journal-title":"Heart"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B174","first-page":"2733","article-title":"2014 ESC Guidelines on diagnosis and management of hypertrophic cardiomyopathy: the task force for the diagnosis and management of hypertrophic cardiomyopathy of the European Society of Cardiology (ESC)","volume":"35","author":"Authors\/Task Force Members","year":"2015","journal-title":"Russ J Cardiol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B175","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/bs.mie.2015.07.028","article-title":"Targeting mitogen-activated protein kinase signaling in mouse models of cardiomyopathy caused by lamin A\/C gene mutations","volume":"568","author":"Muchir","year":"2016","journal-title":"Methods Enzymol"},{"key":"key\n\t\t\t\t20180720091914_cvy122-B176","doi-asserted-by":"crossref","first-page":"2029","DOI":"10.1111\/bph.12461","article-title":"First-in-class cardiolipin-protective compound as a therapeutic agent to restore mitochondrial bioenergetics","volume":"171","author":"Szeto","year":"2014","journal-title":"Br J Pharmacol"}],"container-title":["Cardiovascular Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/cardiovascres\/article-pdf\/114\/10\/1287\/25195464\/cvy122.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,18]],"date-time":"2019-10-18T00:15:46Z","timestamp":1571357746000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/cardiovascres\/article\/114\/10\/1287\/5001810"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5,23]]},"references-count":176,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2018,5,23]]},"published-print":{"date-parts":[[2018,8,1]]}},"URL":"https:\/\/doi.org\/10.1093\/cvr\/cvy122","relation":{},"ISSN":["0008-6363","1755-3245"],"issn-type":[{"value":"0008-6363","type":"print"},{"value":"1755-3245","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2018,8,1]]},"published":{"date-parts":[[2018,5,23]]}}}