{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T21:37:18Z","timestamp":1772660238436,"version":"3.50.1"},"reference-count":50,"publisher":"Oxford University Press (OUP)","issue":"18","license":[{"start":{"date-parts":[[2022,9,5]],"date-time":"2022-09-05T00:00:00Z","timestamp":1662336000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"FH Europe"},{"name":"Slovenian Presidency"},{"DOI":"10.13039\/501100000780","name":"European Union","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,12,21]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Familial hypercholesterolaemia (FH) is under-recognized and under-treated in Europe leading to significantly higher risk for premature heart disease in those affected. As treatment beginning early in life is highly effective in preventing heart disease and cost-effective in these patients, screening for FH is crucial. It has therefore now been recognized by the European Commission Public Health Best Practice Portal as an effective strategy. Model programmes exist in Europe to identify young individuals with FH, which are based on cascade screening of first-degree relatives of affected individuals, universal screening for high cholesterol, opportunistic screening of high-risk individuals, or a combination of the above approaches. Recommendations presented herein to improve identification of FH emphasize that every country should have an FH screening programme. These programmes should be adapted from existing strategies to best fit the individual country\u2019s healthcare system, governments should provide financial support for these programmes and related care, and further research to optimize care and implementations should be conducted.<\/jats:p>","DOI":"10.1093\/eurjpc\/zwac200","type":"journal-article","created":{"date-parts":[[2022,9,2]],"date-time":"2022-09-02T20:16:22Z","timestamp":1662149782000},"page":"2301-2311","source":"Crossref","is-referenced-by-count":73,"title":["Paediatric familial hypercholesterolaemia screening in Europe: public policy background and recommendations"],"prefix":"10.1093","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8557-7225","authenticated-orcid":false,"given":"Samuel S","family":"Gidding","sequence":"first","affiliation":[{"name":"The European FH Patient Network (FH Europe), Star House, Star Hill , Rochester, Kent ME1 1UX , UK"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6223-5671","authenticated-orcid":false,"given":"Albert","family":"Wiegman","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Amsterdam University Medical Centers, University of Amsterdam , Meibergdreef 9, 1105 AZ Amsterdam , The Netherlands"}]},{"given":"Urh","family":"Groselj","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Diabetes, and Metabolic Diseases, University Children\u2019s Hospital, University Medical Centre Ljubljana , Bohori\u010deva ulica 20, Ljubljana , Slovenia"}]},{"given":"Tomas","family":"Freiberger","sequence":"additional","affiliation":[{"name":"Centre for Cardiovascular Surgery and Transplantation , Peka\u0159sk\u00e1 53, 656 91 Brno , Czech Republic"},{"name":"Medical Faculty, Masaryk University , Kamenice 5, 625 00 Brno , Czech Republic"}]},{"given":"Noel","family":"Peretti","sequence":"additional","affiliation":[{"name":"Department of Pediatric Gastroenterology-Hepatology and Nutrition, Hospices Civil de Lyon HCL, H\u00f4pital Femme Mere Enfant HFME, Bron , France"},{"name":"Univ-Lyon, CarMeN Laboratory, INSERM U1060, INRAE U1397, Universit\u00e9 Claude Bernard Lyon-1 , Oullins, Lyon , France"}]},{"given":"Kanika I","family":"Dharmayat","sequence":"additional","affiliation":[{"name":"Imperial Centre for Cardiovascular Disease Prevention, Department of Primary Care and Public Health, Imperial College London , St Dunstan\u2019s Road, London W6 8RP , UK"}]},{"given":"Magdalena","family":"Daccord","sequence":"additional","affiliation":[{"name":"The European FH Patient Network (FH Europe), Star House, Star Hill , Rochester, Kent ME1 1UX , UK"}]},{"given":"Nicola","family":"Bedlington","sequence":"additional","affiliation":[{"name":"The European FH Patient Network (FH Europe), Star House, Star Hill , Rochester, Kent ME1 1UX , UK"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7843-8107","authenticated-orcid":false,"given":"Jaka","family":"Sikonja","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Diabetes, and Metabolic Diseases, University Children\u2019s Hospital, University Medical Centre Ljubljana , Bohori\u010deva ulica 20, Ljubljana , Slovenia"}]},{"given":"Kausik K","family":"Ray","sequence":"additional","affiliation":[{"name":"Imperial Centre for Cardiovascular Disease Prevention, Department of Primary Care and Public Health, Imperial College London , St Dunstan\u2019s Road, London W6 8RP , UK"}]},{"given":"Raul D","family":"Santos","sequence":"additional","affiliation":[{"name":"Heart Institute (InCor), University of Sao Paulo Medical School Hospital , Sao Paulo , Brazil"},{"name":"Preventive Medicine Centre and Cardiology Program, Hospital Israelita Albert Einstein , Sao Paulo , Brazil"},{"name":"International Atherosclerosis Society (IAS) , Milan , Italy"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3065-530X","authenticated-orcid":false,"given":"Martin","family":"Halle","sequence":"additional","affiliation":[{"name":"Department of Prevention and Sports Medicine, Faculty of Medicine, University Hospital \u2018Klinikum rechts der Isar\u2019, Technical University Munich , Munich , Germany"},{"name":"DZHK (Deutsches Zentrum f\u00fcr Herz-Kreislauf-Forschung), partner site Munich, Munich Heart Alliance , Munich , Germany"}]},{"given":"Lale","family":"Tokg\u00f6zo\u011flu","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Hacettepe University, Ankara , Turkey"}]},{"given":"I\u00f1aki","family":"Guti\u00e9rrez-Ibarluzea","sequence":"additional","affiliation":[{"name":"Head of Knowledge Management and Health Technology Assessment, Basque Foundation for Health Innovation and Research (BIOEF) , Ronda de Azkue, 1, 48902 Barakaldo (Bizkaia), Basque Country , Spain"}]},{"given":"Fausto J","family":"Pinto","sequence":"additional","affiliation":[{"name":"World Heart Federation , Geneva , Switzerland"},{"name":"Cardiovascular Department, CCUL, CAML, Lisbon School of Medicine, University of Lisbon , Portugal"}]},{"given":"Marius","family":"Geanta","sequence":"additional","affiliation":[{"name":"The European FH Patient Network (FH Europe), Star House, Star Hill , Rochester, Kent ME1 1UX , UK"}]}],"member":"286","published-online":{"date-parts":[[2022,9,5]]},"reference":[{"key":"2022122119523837700_zwac200-B1","doi-asserted-by":"crossref","first-page":"2425","DOI":"10.1093\/eurheartj\/ehv157","article-title":"Familial hypercholesterolaemia in children and adolescents: gaining decades of life by optimizing detection and treatment","volume":"36","author":"Wiegman","year":"2015","journal-title":"Eur Heart J"},{"key":"2022122119523837700_zwac200-B2","doi-asserted-by":"crossref","first-page":"2578","DOI":"10.1016\/j.jacc.2016.03.520","article-title":"Diagnostic yield and 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