{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T12:32:15Z","timestamp":1787229135222,"version":"build-2736575974"},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:00:00Z","timestamp":1756339200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"STAGE"},{"name":"European Union\u2019s Horizon Europe Research and Innovation Programme","award":["n\u00b0101137146"],"award-info":[{"award-number":["n\u00b0101137146"]}]},{"name":"Horizon Europe Project STAGE","award":["n\u00b010112787"],"award-info":[{"award-number":["n\u00b010112787"]}]},{"name":"Beta Technology","award":["n\u00b010099041"],"award-info":[{"award-number":["n\u00b010099041"]}]},{"DOI":"10.13039\/501100000883","name":"University of Bristol","doi-asserted-by":"publisher","award":["n\u00b010109957"],"award-info":[{"award-number":["n\u00b010109957"]}],"id":[{"id":"10.13039\/501100000883","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000761","name":"Imperial College London","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000761","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Geoscience and Health Cohort Consortium"},{"name":"Netherlands Organization for Scientific Research"},{"DOI":"10.13039\/501100001826","name":"Netherlands Organization for Health Research and Development","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001826","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Ageing populations and longer life expectancies challenge healthcare systems due to rising noncommunicable diseases (NCDs) and multi-morbidity. Designing healthier living environments may reduce population risks of NCD onset, but knowledge is needed on environmental factors related to NCDs in older adults. We therefore examined associations between residential neighbourhood built, physico-chemical, and sociodemographic environmental factors and NCD prevalence in the Netherlands among older adults. Cross-sectional data from 1578 older adults from the Longitudinal Aging Study Amsterdam (2008\u201309) were matched with environmental data from the Dutch Geoscience and Health Cohort Consortium (GECCO). Multivariable logistic regression analyses were conducted to assess the odds of having a single NCD versus no NCD and multi-morbidity versus no NCD, adjusted for sociodemographic factors. Participants had a mean age of 73.2\u2009years, 55% were female, and 77% reported at least one NCD. Multi-morbidity was more common in women, who were also older and had lower education and income. Higher green space density within 500\u2009m was significantly associated with lower odds of single NCD [odds ratio (OR): 0.52, 95% confidence interval (CI): 0.33\u20130.83]. A higher number of cars in a household also showed lower odds of single NCD (OR: 0.14, 95% CI: 0.04\u20130.55). No significant associations were observed for physico-chemical exposures. Results were consistent in sensitivity analyses. The findings underscore the need for urban planning and policies that support healthy ageing while embracing a longevity-ready perspective, accounting for the built, physico-chemical, and sociodemographic environments across the life-course.<\/jats:p>","DOI":"10.1093\/eurpub\/ckaf127","type":"journal-article","created":{"date-parts":[[2025,7,15]],"date-time":"2025-07-15T13:15:50Z","timestamp":1752585350000},"page":"1184-1190","source":"Crossref","is-referenced-by-count":2,"title":["Exposome factors associated with multi-morbidity in older adults: a discovery-based cross-sectional analysis in the Longitudinal Aging Study Amsterdam"],"prefix":"10.1093","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9356-163X","authenticated-orcid":false,"given":"Diana J","family":"Mora","sequence":"first","affiliation":[{"name":"Department of Surgery, Medical and Social Sciences, Universidad de Alcal\u00e1 , Alcal\u00e1 de Henares,","place":["Spain"]},{"name":"Department of Quantitative Methods in Public Health, \u00c9cole des Hautes \u00c9tudes en Sant\u00e9 Publique , University of Rennes, Rennes,","place":["France"]},{"name":"Department of Epidemiology and Data Science, Amsterdam UMC , Amsterdam,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8551-6748","authenticated-orcid":false,"given":"Jeroen","family":"Lakerveld","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Data Science, Amsterdam UMC , Amsterdam,","place":["The Netherlands"]},{"name":"Health Behaviors and Chronic Diseases, Amsterdam Public Health Research Institute , Amsterdam,","place":["The Netherlands"]},{"name":"Upstream Team, Amsterdam UMC , Amsterdam,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9703-4570","authenticated-orcid":false,"given":"Laura A","family":"Schaap","sequence":"additional","affiliation":[{"name":"Health Behaviors and Chronic Diseases, Amsterdam Public Health Research Institute , Amsterdam,","place":["The Netherlands"]},{"name":"Aging and Later Life, Amsterdam Public Health Research Institute , Amsterdam,","place":["The Netherlands"]},{"name":"Department of Health Sciences, Faculty of Science, Amsterdam Public Health Research Institute , Amsterdam,","place":["The Netherlands"]},{"name":"Movement Sciences, Vrije Universiteit Amsterdam , Amsterdam,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9683-6256","authenticated-orcid":false,"given":"M\u00e9lanie","family":"Bertin","sequence":"additional","affiliation":[{"name":"Department of Quantitative Methods in Public Health, \u00c9cole des Hautes \u00c9tudes en Sant\u00e9 Publique , University of Rennes, Rennes,","place":["France"]},{"name":"Ar\u00e8nes\u2014UMR 6051, Centre National de la Recherche Scientifique , Rennes,","place":["France"]},{"name":"Recherche sur les Services et Management en Sant\u00e9\u2014U1309, Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale , Rennes,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3152-6200","authenticated-orcid":false,"given":"Natasja M","family":"van Schoor","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Data Science, Amsterdam UMC , Amsterdam,","place":["The Netherlands"]},{"name":"Aging and Later Life, Amsterdam Public Health Research Institute , Amsterdam,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6559-942X","authenticated-orcid":false,"given":"Bram J","family":"Berntzen","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Data Science, Amsterdam UMC , Amsterdam,","place":["The Netherlands"]},{"name":"Health Behaviors and Chronic Diseases, Amsterdam Public Health Research Institute , Amsterdam,","place":["The Netherlands"]},{"name":"Upstream Team, Amsterdam UMC , Amsterdam,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,8,28]]},"reference":[{"key":"2025121614263165600_ckaf127-B1","doi-asserted-by":"publisher","first-page":"21","DOI":"10.15256\/joc.2016.6.74","article-title":"Addressing multimorbidity to improve healthcare and economic sustainability","volume":"6","author":"Colombo","year":"2016","journal-title":"J Comorb"},{"key":"2025121614263165600_ckaf127-B2","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1093\/eurpub\/ckz118","article-title":"Healthcare use in patients with multimorbidity","volume":"30","author":"Quinaz Romana","year":"2020","journal-title":"Eur J Public 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