{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:00:00Z","timestamp":1753876800629,"version":"3.41.2"},"reference-count":35,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,12,7]]},"DOI":"10.1093\/femsyr\/foac058","type":"journal-article","created":{"date-parts":[[2022,12,7]],"date-time":"2022-12-07T05:52:48Z","timestamp":1670392368000},"source":"Crossref","is-referenced-by-count":1,"title":["<i>Saccharomyces eubayanus<\/i>\u2014a tale of endless mysteries"],"prefix":"10.1093","volume":"22","author":[{"given":"Jos\u00e9 Paulo","family":"Sampaio","sequence":"first","affiliation":[{"name":"UCIBIO, Departamento de Ci\u00eancias da Vida, Faculdade de Ci\u00eancias e Tecnologia, Universidade Nova de Lisboa , 2829-516 Caparica , Portugal"}]}],"member":"286","published-online":{"date-parts":[[2022,12,7]]},"reference":[{"key":"2022120700311539000_bib1","doi-asserted-by":"crossref","first-page":"4044","DOI":"10.1038\/ncomms5044","article-title":"A Gondwanan imprint on global diversity and domestication of wine and cider yeast Saccharomyces uvarum","volume":"5","author":"Almeida","year":"2014","journal-title":"Nat Commun"},{"key":"2022120700311539000_bib2","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1111\/1758-2229.12724","article-title":"Targeted metagenomics approach to capture the biodiversity of Saccharomyces genus in wild environments","volume":"11","author":"Alsammar","year":"2019","journal-title":"Environ Microbiol Rep"},{"key":"2022120700311539000_bib3","doi-asserted-by":"crossref","first-page":"e1007786","DOI":"10.1371\/journal.pgen.1007786","article-title":"Evolution of a novel chimeric maltotriose transporter in Saccharomyces eubayanus from parent proteins unable to perform this function","volume":"15","author":"Baker","year":"2019","journal-title":"PLos Genet"},{"key":"2022120700311539000_bib4","doi-asserted-by":"crossref","DOI":"10.1093\/femsyr\/foac053","article-title":"Identification of European isolates of the lager yeast parent Saccharomyces eubayanus","author":"Bergin","year":"2022","journal-title":"FEMS Yeast Res"},{"key":"2022120700311539000_bib5","doi-asserted-by":"crossref","first-page":"R380","DOI":"10.1016\/j.cub.2014.04.031","article-title":"Evidence for a far east Asian origin of lager beer yeast","volume":"24","author":"Bing","year":"2014","journal-title":"Curr Biol"},{"key":"2022120700311539000_bib6","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/S0065-2164(09)69006-7","article-title":"Chapter 6: the genomes of lager yeasts","volume":"69","author":"Bond","year":"2009","journal-title":"Adv Appl Microbiol"},{"key":"2022120700311539000_bib7","doi-asserted-by":"crossref","first-page":"e01516","DOI":"10.1128\/AEM.01516-19","article-title":"Himalayan Saccharomyces eubayanus genome sequences reveal genetic markers explaining heterotic maltotriose consumption by Saccharomyces pastorianus hybrids","volume":"85","author":"Brouwers","year":"2019","journal-title":"Appl Environ Microbiol"},{"key":"2022120700311539000_bib8","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1534\/genetics.113.152918","article-title":"A new system for comparative functional genomics of Saccharomyces yeasts","volume":"195","author":"Caudy","year":"2013","journal-title":"Genetics"},{"key":"2022120700311539000_bib9","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1126\/science.1084337","article-title":"Finding functional features in Saccharomyces genomes by phylogenetic footprinting","volume":"301","author":"Cliften","year":"2003","journal-title":"Science"},{"volume-title":"A History of Brewing","year":"1975","author":"Corran","key":"2022120700311539000_bib10"},{"key":"2022120700311539000_bib11","doi-asserted-by":"crossref","first-page":"1610","DOI":"10.1101\/gr.076075.108","article-title":"Reconstruction of the genome origins and evolution of the hybrid lager yeast Saccharomyces pastorianus","volume":"18","author":"Dunn","year":"2008","journal-title":"Genome Res"},{"key":"2022120700311539000_bib12","doi-asserted-by":"crossref","first-page":"3732","DOI":"10.1111\/1462-2920.14375","article-title":"Phylogeography of the wild lager-brewing ancestor (Saccharomyces eubayanus) in Patagonia","volume":"20","author":"Eizaguirre","year":"2018","journal-title":"Environ Microbiol"},{"key":"2022120700311539000_bib13","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1111\/1462-2920.13107","article-title":"Saccharomyces eubayanus and Saccharomyces arboricola reside in North Island native New Zealand forests","volume":"18","author":"Gayevskiy","year":"2016","journal-title":"Environ Microbiol"},{"key":"2022120700311539000_bib14","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/femsyr\/fov005","article-title":"S. cerevisiae \u00d7 S . eubayanus interspecific hybrid, the best of both worlds and beyond","volume":"15","author":"Hebly","year":"2015","journal-title":"FEMS Yeast Res"},{"key":"2022120700311539000_bib15","article-title":"Brewing yeast history and the lager yeast myth","author":"Hutzler","year":"2022","journal-title":"FEMS Yeast Res"},{"key":"2022120700311539000_bib16","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1038\/nature01644","article-title":"Sequencing and comparison of yeast species to identify genes and regulatory elements","volume":"423","author":"Kellis","year":"2003","journal-title":"Nature"},{"key":"2022120700311539000_bib17","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1007\/s10295-015-1597-6","article-title":"New lager yeast strains generated by interspecific hybridization","volume":"42","author":"Krogerus","year":"2015","journal-title":"J Ind Microbiol Biotechnol"},{"key":"2022120700311539000_bib18","doi-asserted-by":"crossref","first-page":"e1008680","DOI":"10.1371\/journal.pgen.1008680","article-title":"Postglacial migration shaped the genomic diversity and global distribution of the wild ancestor of lager-brewing hybrids","volume":"16","author":"Langdon","year":"2020","journal-title":"PLos Genet"},{"key":"2022120700311539000_bib19","doi-asserted-by":"crossref","first-page":"14539","DOI":"10.1073\/pnas.1105430108","article-title":"Microbe domestication and the identification of the wild genetic stock of lager-brewing yeast","volume":"108","author":"Libkind","year":"2011","journal-title":"Proc Natl Acad Sci"},{"key":"2022120700311539000_bib20","first-page":"77","article-title":"Three newly delimited species of Saccharomyces sensu stricto","volume-title":"Antonie Van Leeuwenhoek","author":"Martini","year":"1987"},{"key":"2022120700311539000_bib21","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/9783527623488.ch1","article-title":"A comprehensive history of beer brewing","volume-title":"Handbook of Brewing Processes, Technology, Markets","author":"Meussdoerffer","year":"2009"},{"key":"2022120700311539000_bib22","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1099\/00207713-48-1-295","article-title":"Phylogenetic analysis of the Saccharomyces cerevisiae group based on polymorphisms of rDNA spacer sequences","volume":"48","author":"Montrocher","year":"1998","journal-title":"Int J Syst Bacteriol"},{"key":"2022120700311539000_bib23","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1093\/dnares\/dsp003","article-title":"Genome sequence of the lager brewing yeast, an interspecies hybrid","volume":"16","author":"Nakao","year":"2009","journal-title":"DNA Res"},{"key":"2022120700311539000_bib24","doi-asserted-by":"crossref","first-page":"e1008777","DOI":"10.1371\/journal.pgen.1008777","article-title":"An Out-of-Patagonia migration explains the worldwide diversity and distribution of Saccharomyces eubayanus lineages","volume":"16","author":"Nespolo","year":"2020","journal-title":"PLos Genet"},{"key":"2022120700311539000_bib25","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/j.femsyr.2004.12.004","article-title":"Evolutionary relationships between the former species and the hybrids and\u202f; reinstatement of (Beijerinck) as a distinct species","volume":"5","author":"Nguyen","year":"2005","journal-title":"FEMS Yeast Res"},{"key":"2022120700311539000_bib26","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1007\/BF02906199","article-title":"Genetic differences between Saccharomyces carlsbergensis and S . cerevisiae. Analysis of chromosome III by single chromosome transfer","volume":"46","author":"Nilsson-Tillgren","year":"1981","journal-title":"Carlsberg Res Commun"},{"key":"2022120700311539000_bib27","first-page":"e00736","article-title":"Draft genome sequence of the yeast Ogataea degrootiae strain UCD465, isolated from soil in Ireland","volume":"10","author":"\u00d3\u00a0Cinn\u00e9ide","year":"2021","journal-title":"Microbiol Resour Announc"},{"key":"2022120700311539000_bib28","doi-asserted-by":"crossref","first-page":"e1006155","DOI":"10.1371\/journal.pgen.1006155","article-title":"Complex ancestries of lager-brewing hybrids were shaped by standing variation in the wild yeast Saccharomyces eubayanus","volume":"12","author":"Peris","year":"2016","journal-title":"PLos Genet"},{"key":"2022120700311539000_bib29","doi-asserted-by":"crossref","first-page":"2031","DOI":"10.1111\/mec.12702","article-title":"Population structure and reticulate evolution of Saccharomyces eubayanus and its lager-brewing hybrids","volume":"23","author":"Peris","year":"2014","journal-title":"Mol Ecol"},{"key":"2022120700311539000_bib30","doi-asserted-by":"crossref","first-page":"3968","DOI":"10.1128\/AEM.02769-05","article-title":"Pure and mixed genetic lines of Saccharomyces bayanus and Saccharomyces pastorianus and their contribution to the lager brewing strain genome","volume":"72","author":"Rainieri","year":"2006","journal-title":"Appl Environ Microbiol"},{"key":"2022120700311539000_bib31","doi-asserted-by":"crossref","first-page":"2144","DOI":"10.1128\/AEM.02396-07","article-title":"Natural populations of Saccharomyces kudriavzevii in Portugal are associated with oak bark and are sympatric with S . cerevisiae and S . paradoxus","volume":"74","author":"Sampaio","year":"2008","journal-title":"Appl Environ Microbiol"},{"key":"2022120700311539000_bib32","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1002\/yea.320101205","article-title":"Consideration of the evolution of the Saccharomyces cerevisiae MEL gene family on the basis of the nucleotide sequences of the genes and their flanking regions","volume":"10","author":"Turakainen","year":"1994","journal-title":"Yeast"},{"key":"2022120700311539000_bib33","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1099\/00207713-35-4-508","article-title":"Deoxyribonucleic acid relatedness among species of the genus Saccharomyces sensu stricto","volume":"35","author":"Vaughan-Martini","year":"1985","journal-title":"Int J Syst Bacteriol"},{"key":"2022120700311539000_bib34","doi-asserted-by":"crossref","first-page":"e00550","DOI":"10.1128\/genomeA.00550-18","article-title":"Draft genome sequence of a highly heterozygous yeast strain from the Metschnikowia pulcherrima subclade, UCD127","volume":"6","author":"Venkatesh","year":"2018","journal-title":"Genome Announc"},{"key":"2022120700311539000_bib35","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1534\/g3.113.010090","article-title":"Genome sequence of Saccharomyces carlsbergensis, the world's first pure culture lager yeast","volume":"4","author":"Walther","year":"2014","journal-title":"G3 Genes Genomes Genet"}],"container-title":["FEMS Yeast Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/femsyr\/article-pdf\/22\/1\/foac058\/47618354\/foac058.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/femsyr\/article-pdf\/22\/1\/foac058\/47618354\/foac058.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,30]],"date-time":"2023-11-30T19:00:24Z","timestamp":1701370824000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/femsyr\/article\/doi\/10.1093\/femsyr\/foac058\/6874781"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022]]},"references-count":35,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,12,7]]}},"URL":"https:\/\/doi.org\/10.1093\/femsyr\/foac058","relation":{},"ISSN":["1567-1364"],"issn-type":[{"type":"electronic","value":"1567-1364"}],"subject":[],"published-other":{"date-parts":[[2022]]},"published":{"date-parts":[[2022]]},"article-number":"foac058"}}