{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T12:04:57Z","timestamp":1773662697268,"version":"3.50.1"},"reference-count":65,"publisher":"Oxford University Press (OUP)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,1,15]]},"DOI":"10.1093\/hmg\/ddp484","type":"journal-article","created":{"date-parts":[[2009,10,21]],"date-time":"2009-10-21T00:14:48Z","timestamp":1256084088000},"page":"250-261","source":"Crossref","is-referenced-by-count":37,"title":["The homeobox gene CHX10\/VSX2 regulates RdCVF promoter activity in the inner retina"],"prefix":"10.1093","volume":"19","author":[{"given":"Sacha","family":"Reichman","sequence":"first","affiliation":[]},{"given":"Ravi Kiran Reddy","family":"Kalathur","sequence":"additional","affiliation":[]},{"given":"Sophie","family":"Lambard","sequence":"additional","affiliation":[]},{"given":"Najate","family":"A\u00eft-Ali","sequence":"additional","affiliation":[]},{"given":"Yanjiang","family":"Yang","sequence":"additional","affiliation":[]},{"given":"Aur\u00e9lie","family":"Lardenois","sequence":"additional","affiliation":[]},{"given":"Raymond","family":"Ripp","sequence":"additional","affiliation":[]},{"given":"Olivier","family":"Poch","sequence":"additional","affiliation":[]},{"given":"Donald J.","family":"Zack","sequence":"additional","affiliation":[]},{"given":"Jos\u00e9-Alain","family":"Sahel","sequence":"additional","affiliation":[]},{"given":"Thierry","family":"L\u00e9veillard","sequence":"additional","affiliation":[]}],"member":"286","published-online":{"date-parts":[[2009,10,20]]},"reference":[{"key":"key\n\t\t\t\t20170522160107_DDP484C1","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1111\/j.1768-322X.2004.tb01414.x","article-title":"Inherited retinal degenerations: therapeutic prospects","volume":"96","author":"Delyfer","year":"2004","journal-title":"Biol. Cell"},{"key":"key\n\t\t\t\t20170522160107_DDP484C2","doi-asserted-by":"crossref","first-page":"1604","DOI":"10.1126\/science.8202715","article-title":"Digenic retinitis pigmentosa due to mutations at the unlinked peripherin\/RDS and ROM1 loci","volume":"264","author":"Kajiwara","year":"1994","journal-title":"Science"},{"key":"key\n\t\t\t\t20170522160107_DDP484C3","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1038\/ng0693-130","article-title":"Recessive mutations in the gene encoding the beta-subunit of rod phosphodiesterase in patients with retinitis pigmentosa","volume":"4","author":"McLaughlin","year":"1993","journal-title":"Nat. Genet."},{"key":"key\n\t\t\t\t20170522160107_DDP484C4","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1038\/ng0692-209","article-title":"A null mutation in the rhodopsin gene causes rod photoreceptor dysfunction and autosomal recessive retinitis pigmentosa","volume":"1","author":"Rosenfeld","year":"1992","journal-title":"Nat. Genet."},{"key":"key\n\t\t\t\t20170522160107_DDP484C5","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1002\/humu.1380020403","article-title":"Rhodopsin mutations in autosomal dominant retinitis pigmentosa","volume":"2","author":"al-Maghtheh","year":"1993","journal-title":"Hum. Mutat."},{"key":"key\n\t\t\t\t20170522160107_DDP484C6","doi-asserted-by":"crossref","first-page":"3249","DOI":"10.1073\/pnas.92.8.3249","article-title":"Mutation spectrum of the gene encoding the beta subunit of rod phosphodiesterase among patients with autosomal recessive retinitis pigmentosa","volume":"92","author":"McLaughlin","year":"1995","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"key\n\t\t\t\t20170522160107_DDP484C7","first-page":"2186","article-title":"Low incidence of retinitis pigmentosa among heterozygous carriers of a specific rhodopsin splice site mutation","volume":"36","author":"Rosenfeld","year":"1995","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"key\n\t\t\t\t20170522160107_DDP484C8","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/0896-6273(93)90072-Y","article-title":"Apoptosis: final common pathway of photoreceptor death in rd, rds, and rhodopsin mutant mice","volume":"11","author":"Chang","year":"1993","journal-title":"Neuron"},{"key":"key\n\t\t\t\t20170522160107_DDP484C9","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1086\/301772","article-title":"Mechanisms of cell death in the inherited retinal degenerations","volume":"62","author":"Travis","year":"1998","journal-title":"Am. J. Hum. Genet."},{"key":"key\n\t\t\t\t20170522160107_DDP484C10","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1038\/347677a0","article-title":"Retinal degeneration in the rd mouse is caused by a defect in the beta subunit of rod cGMP-phosphodiesterase","volume":"347","author":"Bowes","year":"1990","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170522160107_DDP484C11","first-page":"489","article-title":"Differential effect of the rd mutation on rods and cones in the mouse retina","volume":"17","author":"Carter-Dawson","year":"1978","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"key\n\t\t\t\t20170522160107_DDP484C12","first-page":"263","article-title":"From mice to men: the cyclic GMP phosphodiesterase gene in vision and disease. The Proctor Lecture","volume":"36","author":"Farber","year":"1995","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"key\n\t\t\t\t20170522160107_DDP484C13","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1001\/archopht.118.6.807","article-title":"Selective transplantation of rods delays cone loss in a retinitis pigmentosa model","volume":"118","author":"Mohand-Said","year":"2000","journal-title":"Arch. Ophthalmol."},{"key":"key\n\t\t\t\t20170522160107_DDP484C14","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1159\/000268027","article-title":"Photoreceptor transplants increase host cone survival in the retinal degeneration (rd) mouse","volume":"29","author":"Mohand-Said","year":"1997","journal-title":"Ophthalmic Res."},{"key":"key\n\t\t\t\t20170522160107_DDP484C15","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/0014-4835(90)90013-K","article-title":"Photoreceptor survival-promoting activity in interphotoreceptor matrix preparations: characterization and partial purification","volume":"50","author":"Hewitt","year":"1990","journal-title":"Exp. Eye Res."},{"key":"key\n\t\t\t\t20170522160107_DDP484C16","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1038\/ng1386","article-title":"Identification and characterization of rod-derived cone viability factor","volume":"36","author":"Leveillard","year":"2004","journal-title":"Nat. Genet."},{"key":"key\n\t\t\t\t20170522160107_DDP484C17","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/0166-2236(89)90021-0","article-title":"The neurotrophic theory and naturally occurring motoneuron death","volume":"12","author":"Oppenheim","year":"1989","journal-title":"Trends Neurosci."},{"key":"key\n\t\t\t\t20170522160107_DDP484C18","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1186\/1471-2199-8-74","article-title":"Rod-derived Cone Viability Factor-2 is a novel bifunctional-thioredoxin-like protein with therapeutic potential","volume":"8","author":"Chalmel","year":"2007","journal-title":"BMC Mol. Biol."},{"key":"key\n\t\t\t\t20170522160107_DDP484C19","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1089\/ars.2007.1550","article-title":"Nucleoredoxin, a novel thioredoxin family member involved in cell growth and differentiation","volume":"9","author":"Funato","year":"2007","journal-title":"Antioxid. Redox. Signal."},{"key":"key\n\t\t\t\t20170522160107_DDP484C20","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1089\/ars.2007.9.25","article-title":"Thioredoxin and related molecules\u2013from biology to health and disease","volume":"9","author":"Lillig","year":"2007","journal-title":"Antioxid. Redox. Signal."},{"key":"key\n\t\t\t\t20170522160107_DDP484C21","first-page":"71","article-title":"Oxidative stress and thioredoxin system","volume":"27","author":"Koharyova","year":"2008","journal-title":"Gen. Physiol. Biophys."},{"key":"key\n\t\t\t\t20170522160107_DDP484C22","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1385\/MN:29:3:229","article-title":"Thioredoxin as a neurotrophic cofactor and an important regulator of neuroprotection","volume":"29","author":"Masutani","year":"2004","journal-title":"Mol. Neurobiol."},{"key":"key\n\t\t\t\t20170522160107_DDP484C23","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1089\/152308604771978309","article-title":"Thioredoxin as a key molecule in redox signaling","volume":"6","author":"Nakamura","year":"2004","journal-title":"Antioxid. Redox. Signal."},{"key":"key\n\t\t\t\t20170522160107_DDP484C24","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1089\/152308604771978345","article-title":"Truncated thioredoxin: physiological functions and mechanism","volume":"6","author":"Pekkari","year":"2004","journal-title":"Antioxid. Redox. Signal."},{"key":"key\n\t\t\t\t20170522160107_DDP484C25","doi-asserted-by":"crossref","first-page":"11300","DOI":"10.1073\/pnas.0604056103","article-title":"Antioxidants reduce cone cell death in a model of retinitis pigmentosa","volume":"103","author":"Komeima","year":"2006","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"key\n\t\t\t\t20170522160107_DDP484C26","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1074\/mcp.M800406-MCP200","article-title":"The thioredoxin-like protein RdCVFL interacts with Tau and inhibits its phosphorylation in the retina","volume":"8","author":"Fridlich","year":"2009","journal-title":"Mol. Cell. Proteomics"},{"key":"key\n\t\t\t\t20170522160107_DDP484C27","doi-asserted-by":"crossref","first-page":"S47","DOI":"10.1097\/00006982-200512001-00020","article-title":"Strategies for delivery of rod-derived cone viability factor","volume":"25","author":"Bennett","year":"2005","journal-title":"Retina"},{"key":"key\n\t\t\t\t20170522160107_DDP484C28","first-page":"3292","article-title":"Encapsulated cell-based delivery of CNTF reduces photoreceptor degeneration in animal models of retinitis pigmentosa","volume":"43","author":"Tao","year":"2002","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"key\n\t\t\t\t20170522160107_DDP484C29","doi-asserted-by":"crossref","first-page":"3896","DOI":"10.1073\/pnas.0600236103","article-title":"Ciliary neurotrophic factor (CNTF) for human retinal degeneration: phase I trial of CNTF delivered by encapsulated cell intraocular implants","volume":"103","author":"Sieving","year":"2006","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"key\n\t\t\t\t20170522160107_DDP484C30","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1038\/mt.2009.28","article-title":"Functional Cone Rescue by RdCVF Protein in a Dominant Model of Retinitis Pigmentosa","volume":"17","author":"Yang","year":"2009","journal-title":"Mol. Ther."},{"key":"key\n\t\t\t\t20170522160107_DDP484C31","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1038\/ng0496-376","article-title":"Ocular retardation mouse caused by Chx10 homeobox null allele: impaired retinal progenitor proliferation and bipolar cell differentiation","volume":"12","author":"Burmeister","year":"1996","journal-title":"Nat. Genet."},{"key":"key\n\t\t\t\t20170522160107_DDP484C32","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/S0925-4773(01)00585-8","article-title":"Vsx1, a rapidly evolving paired-like homeobox gene expressed in cone bipolar cells","volume":"109","author":"Chow","year":"2001","journal-title":"Mech. Dev."},{"key":"key\n\t\t\t\t20170522160107_DDP484C33","first-page":"627","article-title":"Homeobox genes in the genetic control of eye development","volume":"44","author":"Lupo","year":"2000","journal-title":"Int. J. Dev. Biol."},{"key":"key\n\t\t\t\t20170522160107_DDP484C34","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1002\/cne.903010308","article-title":"Rod bipolar cells in the mammalian retina show protein kinase C-like immunoreactivity","volume":"301","author":"Greferath","year":"1990","journal-title":"J. Comp. Neurol."},{"key":"key\n\t\t\t\t20170522160107_DDP484C35","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.exer.2007.03.004","article-title":"Focus on molecules: homeobox protein Chx10","volume":"86","author":"Liang","year":"2008","journal-title":"Exp. Eye Res."},{"key":"key\n\t\t\t\t20170522160107_DDP484C36","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/0896-6273(94)90354-9","article-title":"Developmental expression of a novel murine homeobox gene (Chx10): evidence for roles in determination of the neuroretina and inner nuclear layer","volume":"13","author":"Liu","year":"1994","journal-title":"Neuron"},{"key":"key\n\t\t\t\t20170522160107_DDP484C37","doi-asserted-by":"crossref","first-page":"12","DOI":"10.2119\/2004-00017.Campochiaro","article-title":"Deficiency of neuropilin 2 suppresses VEGF-induced retinal neovascularization","volume":"10","author":"Shen","year":"2004","journal-title":"Mol. Med."},{"key":"key\n\t\t\t\t20170522160107_DDP484C38","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.brainres.2007.06.007","article-title":"Negative regulation of Vsx1 by its paralog Chx10\/Vsx2 is conserved in the vertebrate retina","volume":"1192","author":"Clark","year":"2008","journal-title":"Brain Res."},{"key":"key\n\t\t\t\t20170522160107_DDP484C39","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1006\/geno.2000.6248","article-title":"RINX(VSX1), a novel homeobox gene expressed in the inner nuclear layer of the adult retina","volume":"67","author":"Hayashi","year":"2000","journal-title":"Genomics"},{"key":"key\n\t\t\t\t20170522160107_DDP484C40","doi-asserted-by":"crossref","first-page":"29612","DOI":"10.1074\/jbc.271.47.29612","article-title":"The bZIP transcription factor Nrl stimulates rhodopsin promoter activity in primary retinal cell cultures","volume":"271","author":"Kumar","year":"1996","journal-title":"J. Biol. Chem."},{"key":"key\n\t\t\t\t20170522160107_DDP484C41","doi-asserted-by":"crossref","first-page":"9662","DOI":"10.1523\/JNEUROSCI.18-23-09662.1998","article-title":"Survival of purified rat photoreceptors in vitro is stimulated directly by fibroblast growth factor-2","volume":"18","author":"Fontaine","year":"1998","journal-title":"J. Neurosci."},{"key":"key\n\t\t\t\t20170522160107_DDP484C42","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1111\/j.1471-4159.2008.05765.x","article-title":"Developmental and daily expression of the Pax4 and Pax6 homeobox genes in the rat retina: localization of Pax4 in photoreceptor cells","volume":"108","author":"Rath","year":"2009","journal-title":"J. Neurochem."},{"key":"key\n\t\t\t\t20170522160107_DDP484C43","doi-asserted-by":"crossref","first-page":"25877","DOI":"10.1074\/jbc.M201407200","article-title":"The rod cGMP-phosphodiesterase beta-subunit promoter is a specific target for Sp4 and is not activated by other Sp proteins or CRX","volume":"277","author":"Lerner","year":"2002","journal-title":"J. Biol. Chem."},{"key":"key\n\t\t\t\t20170522160107_DDP484C44","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1242\/dev.128.8.1313","article-title":"Roles of homeobox and bHLH genes in specification of a retinal cell type","volume":"128","author":"Hatakeyama","year":"2001","journal-title":"Development"},{"key":"key\n\t\t\t\t20170522160107_DDP484C45","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/j.ydbio.2004.03.039","article-title":"Genetic analysis of the homeodomain transcription factor Chx10 in the retina using a novel multifunctional BAC transgenic mouse reporter","volume":"271","author":"Rowan","year":"2004","journal-title":"Dev. Biol."},{"key":"key\n\t\t\t\t20170522160107_DDP484C46","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/S0925-4773(99)00049-0","article-title":"Expression of the optx2 homeobox gene during mouse development","volume":"83","author":"Toy","year":"1999","journal-title":"Mech. Dev."},{"key":"key\n\t\t\t\t20170522160107_DDP484C47","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1093\/hmg\/ddi084","article-title":"Natural antisense transcripts associated with genes involved in eye development","volume":"14","author":"Alfano","year":"2005","journal-title":"Hum. Mol. Genet."},{"key":"key\n\t\t\t\t20170522160107_DDP484C48","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/S0092-8674(00)80439-0","article-title":"Crx, a novel otx-like homeobox gene, shows photoreceptor-specific expression and regulates photoreceptor differentiation","volume":"91","author":"Furukawa","year":"1997","journal-title":"Cell"},{"key":"key\n\t\t\t\t20170522160107_DDP484C49","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.1093\/hmg\/10.15.1571","article-title":"Temporal and spatial expression patterns of the CRX transcription factor and its downstream targets. Critical differences during human and mouse eye development","volume":"10","author":"Bibb","year":"2001","journal-title":"Hum. Mol. Genet."},{"key":"key\n\t\t\t\t20170522160107_DDP484C50","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1016\/0014-4835(92)90148-L","article-title":"Photoreceptor-specific mRNAs in mice carrying different allelic combinations at the rd and rds loci","volume":"54","author":"Viczian","year":"1992","journal-title":"Exp. Eye Res."},{"key":"key\n\t\t\t\t20170522160107_DDP484C51","doi-asserted-by":"crossref","first-page":"2633","DOI":"10.1021\/bi00709a025","article-title":"Ribonucleic acid isolated by cesium chloride centrifugation","volume":"13","author":"Glisin","year":"1974","journal-title":"Biochemistry"},{"key":"key\n\t\t\t\t20170522160107_DDP484C52","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1089\/cmb.1994.1.191","article-title":"TRANSFAC retrieval program: a network model database of eukaryotic transcription regulating sequences and proteins","volume":"1","author":"Knuppel","year":"1994","journal-title":"J. Comput. Biol."},{"key":"key\n\t\t\t\t20170522160107_DDP484C53","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1093\/nar\/24.1.238","article-title":"TRANSFAC: a database on transcription factors and their DNA binding sites","volume":"24","author":"Wingender","year":"1996","journal-title":"Nucleic Acids Res."},{"key":"key\n\t\t\t\t20170522160107_DDP484C54","doi-asserted-by":"crossref","first-page":"3576","DOI":"10.1093\/nar\/gkg585","article-title":"MATCH: A tool for searching transcription factor binding sites in DNA sequences","volume":"31","author":"Kel","year":"2003","journal-title":"Nucleic Acids Res."},{"key":"key\n\t\t\t\t20170522160107_DDP484C55","doi-asserted-by":"crossref","first-page":"W578","DOI":"10.1093\/nar\/gkl193","article-title":"PromAn: an integrated knowledge-based web server dedicated to promoter analysis","volume":"34","author":"Lardenois","year":"2006","journal-title":"Nucleic Acids Res."},{"key":"key\n\t\t\t\t20170522160107_DDP484C56","doi-asserted-by":"crossref","first-page":"5794","DOI":"10.1073\/pnas.77.10.5794","article-title":"Isolation and partial characterization of the Drosophila alcohol dehydrogenase gene","volume":"77","author":"Goldberg","year":"1980","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"key\n\t\t\t\t20170522160107_DDP484C57","doi-asserted-by":"crossref","first-page":"4743","DOI":"10.1021\/bi00640a033","article-title":"RNA molecular weight determinations by gel electrophoresis under denaturing conditions, a critical reexamination","volume":"16","author":"Lehrach","year":"1977","journal-title":"Biochemistry"},{"key":"key\n\t\t\t\t20170522160107_DDP484C58","first-page":"398","article-title":"Optimizing the northern blot procedure","volume":"8","author":"Rosen","year":"1990","journal-title":"Biotechniques"},{"key":"key\n\t\t\t\t20170522160107_DDP484C59","doi-asserted-by":"crossref","first-page":"8357","DOI":"10.1073\/pnas.95.14.8357","article-title":"Normal retina releases a diffusible factor stimulating cone survival in the retinal degeneration mouse","volume":"95","author":"Mohand-Said","year":"1998","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"key\n\t\t\t\t20170522160107_DDP484C60","doi-asserted-by":"crossref","first-page":"1675","DOI":"10.1038\/nbt1296-1675","article-title":"Expression monitoring by hybridization to high-density oligonucleotide arrays","volume":"14","author":"Lockhart","year":"1996","journal-title":"Nat. Biotechnol."},{"key":"key\n\t\t\t\t20170522160107_DDP484C61","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1093\/bioinformatics\/btm556","article-title":"RReportGenerator: automatic reports from routine statistical analysis using R","volume":"24","author":"Raffelsberger","year":"2008","journal-title":"Bioinformatics"},{"key":"key\n\t\t\t\t20170522160107_DDP484C62","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1186\/1471-2164-9-208","article-title":"RETINOBASE: a web database, data mining and analysis platform for gene expression data on retina","volume":"9","author":"Kalathur","year":"2008","journal-title":"BMC Genomics"},{"key":"key\n\t\t\t\t20170522160107_DDP484C63","first-page":"61","article-title":"Expression analysis of murine genes using in situ hybridization with radioactive and nonradioactively labeled RNA probes","volume":"326","author":"Chotteau-Lelievre","year":"2006","journal-title":"Methods Mol. Biol."},{"key":"key\n\t\t\t\t20170522160107_DDP484C64","doi-asserted-by":"crossref","first-page":"1978","DOI":"10.1093\/emboj\/21.8.1978","article-title":"Interferon-gamma-induced chromatin remodeling at the CIITA locus is BRG1 dependent","volume":"21","author":"Pattenden","year":"2002","journal-title":"Embo. J."},{"key":"key\n\t\t\t\t20170522160107_DDP484C65","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1074\/jbc.M509470200","article-title":"CHX10 targets a subset of photoreceptor genes","volume":"281","author":"Dorval","year":"2006","journal-title":"J. Biol. Chem."}],"container-title":["Human Molecular Genetics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/hmg\/article-pdf\/19\/2\/250\/17249824\/ddp484.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,12]],"date-time":"2021-10-12T17:11:55Z","timestamp":1634058715000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/hmg\/article-lookup\/doi\/10.1093\/hmg\/ddp484"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,10,20]]},"references-count":65,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2009,10,20]]},"published-print":{"date-parts":[[2010,1,15]]}},"URL":"https:\/\/doi.org\/10.1093\/hmg\/ddp484","relation":{},"ISSN":["1460-2083","0964-6906"],"issn-type":[{"value":"1460-2083","type":"electronic"},{"value":"0964-6906","type":"print"}],"subject":[],"published":{"date-parts":[[2009,10,20]]}}}