{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T14:23:23Z","timestamp":1791815003919,"version":"4.3.4"},"reference-count":71,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,1,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Cultivated chrysanthemum (Chrysanthemum \u00d7 morifolium Ramat.) is a beloved ornamental crop due to the diverse capitula types among varieties, but the molecular mechanism of capitulum development remains unclear. Here, we report a 2.60 Gb chromosome-scale reference genome of C. lavandulifolium, a wild Chrysanthemum species found in China, Korea and Japan. The evolutionary analysis of the genome revealed that only recent tandem duplications occurred in the C. lavandulifolium genome after the shared whole genome triplication (WGT) in Asteraceae. Based on the transcriptomic profiling of six important developmental stages of the radiate capitulum in C. lavandulifolium, we found genes in the MADS-box, TCP, NAC and LOB gene families that were involved in disc and ray floret primordia differentiation. Notably, NAM and LOB30 homologs were specifically expressed in the radiate capitulum, suggesting their pivotal roles in the genetic network of disc and ray floret primordia differentiation in chrysanthemum. The present study not only provides a high-quality reference genome of chrysanthemum but also provides insight into the molecular mechanism underlying the diverse capitulum types in chrysanthemum.<\/jats:p>","DOI":"10.1093\/hr\/uhab022","type":"journal-article","created":{"date-parts":[[2022,1,18]],"date-time":"2022-01-18T01:54:07Z","timestamp":1642470847000},"source":"Crossref","is-referenced-by-count":55,"title":["The\n                    <i>Chrysanthemum lavandulifolium<\/i>\n                    genome and the molecular mechanism underlying diverse capitulum types"],"prefix":"10.1093","volume":"9","author":[{"given":"Xiaohui","family":"Wen","sequence":"first","affiliation":[{"name":"Beijing Forestry University Beijing Key Laboratory of Ornamental Plants Germplasm Innovation & Molecular Breeding, National Engineering Research Center for Floriculture, Beijing Laboratory of Urban and Rural Ecological Environment, Key Laboratory of Genetics and Breeding in Forest Trees and Ornamental Plants of the Ministry of Education, School of Landscape Architecture, , No. 35 East Qinghua Road, Beijing 100083, China"},{"name":"Zhejiang University Genomics and Genetic Engineering Laboratory of Ornamental Plants, Department of Horticulture, College of Agriculture and Biotechnology, , No. 866 Yuhangtang Road, Hangzhou 310058, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junzhuo","family":"Li","sequence":"additional","affiliation":[{"name":"Beijing Forestry University Beijing Key Laboratory of Ornamental Plants Germplasm Innovation & Molecular Breeding, National Engineering Research Center for Floriculture, Beijing Laboratory of Urban and Rural Ecological Environment, Key Laboratory of Genetics and Breeding in Forest Trees and Ornamental Plants of the Ministry of Education, School of Landscape Architecture, , No. 35 East Qinghua Road, Beijing 100083, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lili","family":"Wang","sequence":"additional","affiliation":[{"name":"Biomarker Technologies Co., Ltd , No. 12 Fuqian Street, Shunyi District, Beijing 101300, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenfei","family":"Lu","sequence":"additional","affiliation":[{"name":"Beijing Forestry University Beijing Key Laboratory of Ornamental Plants Germplasm Innovation & Molecular Breeding, National Engineering Research Center for Floriculture, Beijing Laboratory of Urban and Rural Ecological Environment, Key Laboratory of Genetics and Breeding in Forest Trees and Ornamental Plants of the Ministry of Education, School of Landscape Architecture, , No. 35 East Qinghua Road, Beijing 100083, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiang","family":"Gao","sequence":"additional","affiliation":[{"name":"Zhejiang University Genomics and Genetic Engineering Laboratory of Ornamental Plants, Department of Horticulture, College of Agriculture and Biotechnology, , No. 866 Yuhangtang Road, Hangzhou 310058, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Xu","sequence":"additional","affiliation":[{"name":"Chinese Academy of Sciences State Key Laboratory of Systematic and Evolutionary Botany, Institute of Botany, , No. 20 Nanxincun, Beijing 100093, China"},{"name":"University of Chinese Academy of Sciences , No.19(A) Yuquan Road, Beijing 100049, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya","family":"Pu","sequence":"additional","affiliation":[{"name":"Beijing Forestry University Beijing Key Laboratory of Ornamental Plants Germplasm Innovation & Molecular Breeding, National Engineering Research Center for Floriculture, Beijing Laboratory of Urban and Rural Ecological Environment, Key Laboratory of Genetics and Breeding in Forest Trees and Ornamental Plants of the Ministry of Education, School of Landscape Architecture, , No. 35 East Qinghua Road, Beijing 100083, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiuling","family":"Zhang","sequence":"additional","affiliation":[{"name":"Beijing Forestry University Beijing Key Laboratory of Ornamental Plants Germplasm Innovation & Molecular Breeding, National Engineering Research Center for Floriculture, Beijing Laboratory of Urban and Rural Ecological Environment, Key Laboratory of Genetics and Breeding in Forest Trees and Ornamental Plants of the Ministry of Education, School of Landscape Architecture, , No. 35 East Qinghua Road, Beijing 100083, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Hong","sequence":"additional","affiliation":[{"name":"Beijing Forestry University Beijing Key Laboratory of Ornamental Plants Germplasm Innovation & Molecular Breeding, National Engineering Research Center for Floriculture, Beijing Laboratory of Urban and Rural Ecological Environment, Key Laboratory of Genetics and Breeding in Forest Trees and Ornamental Plants of the Ministry of Education, School of Landscape Architecture, , No. 35 East Qinghua Road, Beijing 100083, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luo","family":"Hong","sequence":"additional","affiliation":[{"name":"Beijing Forestry University Beijing Key Laboratory of Ornamental Plants Germplasm Innovation & Molecular Breeding, National Engineering Research Center for Floriculture, Beijing Laboratory of Urban and Rural Ecological Environment, Key Laboratory of Genetics and Breeding in Forest Trees and Ornamental Plants of the Ministry of Education, School of Landscape Architecture, , No. 35 East Qinghua Road, Beijing 100083, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"He","family":"Huang","sequence":"additional","affiliation":[{"name":"Beijing Forestry University Beijing Key Laboratory of Ornamental Plants Germplasm Innovation & Molecular Breeding, National Engineering Research Center for Floriculture, Beijing Laboratory of Urban and Rural Ecological Environment, Key Laboratory of Genetics and Breeding in Forest Trees and Ornamental Plants of the Ministry of Education, School of Landscape Architecture, , No. 35 East Qinghua Road, Beijing 100083, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huaigen","family":"Xin","sequence":"additional","affiliation":[{"name":"Biomarker Technologies Co., Ltd , No. 12 Fuqian Street, Shunyi District, Beijing 101300, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyun","family":"Wu","sequence":"additional","affiliation":[{"name":"Beijing Forestry University Beijing Key Laboratory of Ornamental Plants Germplasm Innovation & Molecular Breeding, National Engineering Research Center for Floriculture, Beijing Laboratory of Urban and Rural Ecological Environment, Key Laboratory of Genetics and Breeding in Forest Trees and Ornamental Plants of the Ministry of Education, School of Landscape Architecture, , No. 35 East Qinghua Road, Beijing 100083, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongru","family":"Kang","sequence":"additional","affiliation":[{"name":"Henan University State Key Laboratory of Crop Stress Adaptation and Improvement, Plant Germplasm Resources and Genetic Laboratory, Kaifeng Key Laboratory of Chrysanthemum Biology, School of Life Sciences, School of Agriculture, , Jinming Road, Kaifeng 475004, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kang","family":"Gao","sequence":"additional","affiliation":[{"name":"Beijing Forestry University Beijing Key Laboratory of Ornamental Plants Germplasm Innovation & Molecular Breeding, National Engineering Research Center for Floriculture, Beijing Laboratory of Urban and Rural Ecological Environment, Key Laboratory of Genetics and Breeding in Forest Trees and Ornamental Plants of the Ministry of Education, School of Landscape Architecture, , No. 35 East Qinghua Road, Beijing 100083, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yajun","family":"Li","sequence":"additional","affiliation":[{"name":"Beijing Forestry University Beijing Key Laboratory of Ornamental Plants Germplasm Innovation & Molecular Breeding, National Engineering Research Center for Floriculture, Beijing Laboratory of Urban and Rural Ecological Environment, Key Laboratory of Genetics and Breeding in Forest Trees and Ornamental Plants of the Ministry of Education, School of Landscape Architecture, , No. 35 East Qinghua Road, Beijing 100083, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaofeng","family":"Ma","sequence":"additional","affiliation":[{"name":"Beijing Forestry University Beijing Key Laboratory of Ornamental Plants Germplasm Innovation & Molecular Breeding, National Engineering Research Center for Floriculture, Beijing Laboratory of Urban and Rural Ecological Environment, Key Laboratory of Genetics and Breeding in Forest Trees and Ornamental Plants of the Ministry of Education, School of Landscape Architecture, , No. 35 East Qinghua Road, Beijing 100083, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuming","family":"Li","sequence":"additional","affiliation":[{"name":"Biomarker Technologies Co., Ltd , No. 12 Fuqian Street, Shunyi District, Beijing 101300, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongkun","family":"Zheng","sequence":"additional","affiliation":[{"name":"Biomarker Technologies Co., Ltd , No. 12 Fuqian Street, Shunyi District, Beijing 101300, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zicheng","family":"Wang","sequence":"additional","affiliation":[{"name":"Henan University State Key Laboratory of Crop Stress Adaptation and Improvement, Plant Germplasm Resources and Genetic Laboratory, Kaifeng Key Laboratory of Chrysanthemum Biology, School of Life Sciences, School of Agriculture, , Jinming Road, Kaifeng 475004, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuannian","family":"Jiao","sequence":"additional","affiliation":[{"name":"Chinese Academy of Sciences State Key Laboratory of Systematic and Evolutionary Botany, Institute of Botany, , No. 20 Nanxincun, Beijing 100093, China"},{"name":"University of Chinese Academy of Sciences , No.19(A) Yuquan Road, Beijing 100049, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liangsheng","family":"Zhang","sequence":"additional","affiliation":[{"name":"Zhejiang University Genomics and Genetic Engineering Laboratory of Ornamental Plants, Department of Horticulture, College of Agriculture and Biotechnology, , No. 866 Yuhangtang Road, Hangzhou 310058, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silan","family":"Dai","sequence":"additional","affiliation":[{"name":"Beijing Forestry University Beijing Key Laboratory of Ornamental Plants Germplasm Innovation & Molecular Breeding, National Engineering Research Center for Floriculture, Beijing Laboratory of Urban and Rural Ecological Environment, Key Laboratory of Genetics and Breeding in Forest Trees and Ornamental Plants of the Ministry of Education, School of Landscape Architecture, , No. 35 East Qinghua Road, Beijing 100083, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,1,20]]},"reference":[{"key":"2022060111180486900_ref1","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1038\/s41438-020-0333-1","article-title":"High-density genetic map construction and identification of loci controlling flower-type traits in chrysanthemum (chrysanthemum \u00d7 morifolium Ramat.)","volume":"7","author":"Song","year":"2020","journal-title":"Horticulture Research"},{"key":"2022060111180486900_ref2","first-page":"1","article-title":"High quality genome of Erigeron breviscapus provides a reference for herbal plants in Asteraceae","volume":"00","author":"He","year":"2020","journal-title":"Mol Ecol Resour"},{"key":"2022060111180486900_ref3","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.1016\/j.molp.2018.10.003","article-title":"The chrysanthemum nankingense genome provides insights into the evolution and diversification of chrysanthemum flowers and medicinal traits","volume":"11","author":"Song","year":"2018","journal-title":"Mol Plant"},{"key":"2022060111180486900_ref4","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1093\/dnares\/dsy048","article-title":"De novo whole-genome assembly in chrysanthemum seticuspe, a model species of chrysanthemums, and its application to genetic and gene discovery analysis","volume":"26","author":"Hirakawa","year":"2019","journal-title":"DNA Res"},{"key":"2022060111180486900_ref5","first-page":"519","article-title":"Gene networks controlling the initiation of flower development","volume-title":"Trends 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