{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T03:58:35Z","timestamp":1773979115535,"version":"3.50.1"},"reference-count":39,"publisher":"Oxford University Press (OUP)","issue":"Supplement_2","license":[{"start":{"date-parts":[[2023,8,31]],"date-time":"2023-08-31T00:00:00Z","timestamp":1693440000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/100000060","name":"NIAID","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["UM1AI068634"],"award-info":[{"award-number":["UM1AI068634"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["UM1 AI068636"],"award-info":[{"award-number":["UM1 AI068636"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["UM1AI106701"],"award-info":[{"award-number":["UM1AI106701"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,8,31]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Prospective evaluations of long COVID in outpatients with coronavirus disease 2019 (COVID-19) are lacking. We aimed to determine the frequency and predictors of long COVID after treatment with the monoclonal antibody bamlanivimab in ACTIV-2\/A5401.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Data were analyzed from participants who received bamlanivimab 700 mg in ACTIV-2 from October 2020 to February 2021. Long COVID was defined as the presence of self-assessed COVID symptoms at week 24. Self-assessed return to pre-COVID health was also examined. Associations were assessed by regression models.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Among 506 participants, median age was 51 years. Half were female, 5% Black\/African American, and 36% Hispanic\/Latino. At 24 weeks, 18% reported long COVID and 15% had not returned to pre-COVID health. Smoking (adjusted risk ratio [aRR], 2.41 [95% confidence interval {CI}, 1.34\u2013 4.32]), female sex (aRR, 1.91 [95% CI, 1.28\u20132.85]), non-Hispanic ethnicity (aRR, 1.92 [95% CI, 1.19\u20133.13]), and presence of symptoms 22\u201328 days posttreatment (aRR, 2.70 [95% CI, 1.63\u20134.46]) were associated with long COVID, but nasal severe acute respiratory syndrome coronavirus 2 RNA was not.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Long COVID occurred despite early, effective monoclonal antibody therapy and was associated with smoking, female sex, and non-Hispanic ethnicity, but not viral burden. The strong association between symptoms 22\u201328 days after treatment and long COVID suggests that processes of long COVID start early and may need early intervention.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Clinical Trials Registration<\/jats:title>\n                  <jats:p>NCT04518410.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/infdis\/jiad286","type":"journal-article","created":{"date-parts":[[2023,8,31]],"date-time":"2023-08-31T07:34:10Z","timestamp":1693467250000},"page":"S126-S135","source":"Crossref","is-referenced-by-count":4,"title":["Long COVID After Bamlanivimab Treatment"],"prefix":"10.1093","volume":"228","author":[{"given":"Teresa H","family":"Evering","sequence":"first","affiliation":[{"name":"Department of Medicine, Weill Cornell Medicine , New York, New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlee B","family":"Moser","sequence":"additional","affiliation":[{"name":"Center for Biostatistics in AIDS Research, Harvard T. 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Chan School of Public Health , Boston, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Davey M","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of California, San Diego , La Jolla"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kara W","family":"Chew","sequence":"additional","affiliation":[{"name":"Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"for the ACTIV-2\/A5401 Study 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