{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T15:41:32Z","timestamp":1770997292380,"version":"3.50.1"},"reference-count":66,"publisher":"Oxford University Press (OUP)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Antimicrobial Chemotherapy"],"published-print":{"date-parts":[[2014,2,1]]},"DOI":"10.1093\/jac\/dkt359","type":"journal-article","created":{"date-parts":[[2013,9,20]],"date-time":"2013-09-20T06:56:56Z","timestamp":1379660216000},"page":"476-482","source":"Crossref","is-referenced-by-count":24,"title":["Differences in nevirapine biotransformation as a factor for its sex-dependent dimorphic profile of adverse drug reactions"],"prefix":"10.1093","volume":"69","author":[{"given":"A. T.","family":"Marinho","sequence":"first","affiliation":[]},{"given":"P. M.","family":"Rodrigues","sequence":"additional","affiliation":[]},{"given":"U.","family":"Caixas","sequence":"additional","affiliation":[]},{"given":"A. M. M.","family":"Antunes","sequence":"additional","affiliation":[]},{"given":"T.","family":"Branco","sequence":"additional","affiliation":[]},{"given":"S. G.","family":"Harjivan","sequence":"additional","affiliation":[]},{"given":"M. M.","family":"Marques","sequence":"additional","affiliation":[]},{"given":"E. C.","family":"Monteiro","sequence":"additional","affiliation":[]},{"given":"S. A.","family":"Pereira","sequence":"additional","affiliation":[]}],"member":"286","published-online":{"date-parts":[[2013,9,19]]},"reference":[{"issue":"6","key":"1_33080679","doi-asserted-by":"publisher","first-page":"884","DOI":"10.1200\/JCO.2008.19.6626","volume":"27","year":"2009","journal-title":"Journal of Clinical Oncology","ISSN":"https:\/\/id.crossref.org\/issn\/0732-183X","issn-type":"print"},{"issue":"1","key":"3_10428782","doi-asserted-by":"publisher","first-page":"9","DOI":"10.2165\/00019053-200018010-00002","volume":"18","author":"Ades","year":"2000","journal-title":"PharmacoEconomics","ISSN":"https:\/\/id.crossref.org\/issn\/1170-7690","issn-type":"print"},{"issue":"2","key":"4_23468977","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1056\/NEJMoa062876","volume":"356","author":"Lockman","year":"2007","journal-title":"New England Journal of Medicine","ISSN":"https:\/\/id.crossref.org\/issn\/0028-4793","issn-type":"print"},{"issue":"2","key":"5_31517815","first-page":"110","volume":"10","author":"Medrano","year":"2008","journal-title":"AIDS reviews","ISSN":"https:\/\/id.crossref.org\/issn\/1139-6121","issn-type":"print"},{"issue":"2","key":"7_38599565","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1086\/520242","volume":"29","year":"1999","journal-title":"Clinical Infectious Diseases","ISSN":"https:\/\/id.crossref.org\/issn\/1058-4838","issn-type":"print"},{"issue":"4","key":"8_30722052","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1111\/j.1468-1293.2008.00552.x","volume":"9","author":"De Lazzari","year":"2008","journal-title":"HIV medicine","ISSN":"https:\/\/id.crossref.org\/issn\/1464-2662","issn-type":"print"},{"issue":"6","key":"9_45608387","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1258\/095646206777323346","volume":"17","author":"Taiwo","year":"2006","journal-title":"International Journal of STD & AIDS","ISSN":"https:\/\/id.crossref.org\/issn\/0956-4624","issn-type":"print"},{"issue":"15","key":"11_6226356","doi-asserted-by":"publisher","first-page":"2082","DOI":"10.1097\/00002030-199815000-00026","volume":"12","author":"Ho","year":"1998","journal-title":"AIDS (London, England)","ISSN":"https:\/\/id.crossref.org\/issn\/0269-9370","issn-type":"print"},{"issue":"12","key":"12_11279109","doi-asserted-by":"publisher","first-page":"1579","DOI":"10.1097\/00002030-200108170-00018","volume":"15","author":"Antinori","year":"2001","journal-title":"AIDS (London, England)","ISSN":"https:\/\/id.crossref.org\/issn\/0269-9370","issn-type":"print"},{"issue":"1","key":"13_38252733","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1086\/317536","volume":"32","year":"2001","journal-title":"Clinical Infectious Diseases","ISSN":"https:\/\/id.crossref.org\/issn\/1058-4838","issn-type":"print"},{"issue":"1","key":"14_18720845","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1097\/00002030-200501030-00014","volume":"19","author":"Martin","year":"2005","journal-title":"AIDS (London, England)","ISSN":"https:\/\/id.crossref.org\/issn\/0269-9370","issn-type":"print"},{"issue":"10","key":"15_39765085","doi-asserted-by":"publisher","first-page":"1271","DOI":"10.1097\/QAD.0b013e32834779df","volume":"25","author":"Yuan","year":"2011","journal-title":"AIDS (London, England)","ISSN":"https:\/\/id.crossref.org\/issn\/0269-9370","issn-type":"print"},{"issue":"7","key":"16_41756530","doi-asserted-by":"publisher","first-page":"833","DOI":"10.1097\/QAD.0b013e328351a521","volume":"26","author":"Dong","year":"2012","journal-title":"AIDS (London, England)","ISSN":"https:\/\/id.crossref.org\/issn\/0269-9370","issn-type":"print"},{"issue":"3","key":"17_37634570","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1001\/jama.2010.1004","volume":"304","author":"Thompson","year":"2010","journal-title":"JAMA","ISSN":"https:\/\/id.crossref.org\/issn\/0098-7484","issn-type":"print"},{"issue":"5-6","key":"18_17823460","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1007\/s00228-003-0613-3","volume":"59","author":"de Maat","year":"2003","journal-title":"European journal of clinical pharmacology","ISSN":"https:\/\/id.crossref.org\/issn\/0031-6970","issn-type":"print"},{"issue":"16","key":"19_17867507","doi-asserted-by":"publisher","first-page":"2399","DOI":"10.1097\/00002030-200311070-00018","volume":"17","author":"Regazzi","year":"2003","journal-title":"AIDS (London, England)","ISSN":"https:\/\/id.crossref.org\/issn\/0269-9370","issn-type":"print"},{"issue":"7","key":"20_18290469","doi-asserted-by":"publisher","first-page":"716","DOI":"10.1089\/0889222041524670","volume":"20","author":"Almond","year":"2004","journal-title":"AIDS research and human retroviruses","ISSN":"https:\/\/id.crossref.org\/issn\/0889-2229","issn-type":"print"},{"issue":"4","key":"21_19278686","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1177\/135965350501000404","volume":"10","author":"Kappelhoff","year":"2005","journal-title":"Antiviral therapy","ISSN":"https:\/\/id.crossref.org\/issn\/1359-6535","issn-type":"print"},{"issue":"6","key":"22_29939410","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1310\/hct0806-391","volume":"8","author":"Hall","year":"2007","journal-title":"HIV clinical trials","ISSN":"https:\/\/id.crossref.org\/issn\/1528-4336","issn-type":"print"},{"issue":"12","key":"23_6377514","doi-asserted-by":"crossref","first-page":"1488","DOI":"10.1016\/S0090-9556(24)14960-4","volume":"27","author":"Erickson","year":"1999","journal-title":"Drug Metabolism and Disposition","ISSN":"https:\/\/id.crossref.org\/issn\/0090-9556","issn-type":"print"},{"issue":"8","key":"24_10902201","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1016\/S0090-9556(24)15239-7","volume":"27","author":"Riska","year":"1999","journal-title":"Drug Metabolism and Disposition","ISSN":"https:\/\/id.crossref.org\/issn\/0090-9556","issn-type":"print"},{"issue":"9","key":"25_31815990","doi-asserted-by":"publisher","first-page":"1862","DOI":"10.1021\/tx800177k","volume":"21","author":"Chen","year":"2008","journal-title":"Chemical research in toxicology","ISSN":"https:\/\/id.crossref.org\/issn\/0893-228X","issn-type":"print"},{"issue":"1","key":"26_35681812","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1124\/dmd.109.028688","volume":"38","year":"2010","journal-title":"Drug Metabolism and Disposition","ISSN":"https:\/\/id.crossref.org\/issn\/0090-9556","issn-type":"print"},{"issue":"5","key":"27_37117114","doi-asserted-by":"publisher","first-page":"888","DOI":"10.1021\/tx900443z","volume":"23","author":"Antunes","year":"2010","journal-title":"Chemical research in toxicology","ISSN":"https:\/\/id.crossref.org\/issn\/0893-228X","issn-type":"print"},{"key":"28_46530656","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.tox.2012.06.013","volume":"301","year":"2012","journal-title":"Toxicology","ISSN":"https:\/\/id.crossref.org\/issn\/0300-483X","issn-type":"print"},{"key":"29_46530657","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1021\/tx4000107","volume":"26","year":"2013","journal-title":"Chemical research in toxicology","ISSN":"https:\/\/id.crossref.org\/issn\/0893-228X","issn-type":"print"},{"issue":"11","key":"30_38071295","doi-asserted-by":"publisher","first-page":"1714","DOI":"10.1021\/tx100186t","volume":"23","author":"Antunes","year":"2010","journal-title":"Chemical research in toxicology","ISSN":"https:\/\/id.crossref.org\/issn\/0893-228X","issn-type":"print"},{"issue":"7","key":"31_34579234","doi-asserted-by":"publisher","first-page":"1557","DOI":"10.1124\/dmd.108.024851","volume":"37","year":"2009","journal-title":"Drug Metabolism and Disposition","ISSN":"https:\/\/id.crossref.org\/issn\/0090-9556","issn-type":"print"},{"key":"32_46530658","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1021\/tx400098z","volume":"26","year":"2013","journal-title":"Chemical research in toxicology","ISSN":"https:\/\/id.crossref.org\/issn\/0893-228X","issn-type":"print"},{"issue":"22","key":"33_40925427","doi-asserted-by":"publisher","first-page":"7822","DOI":"10.1039\/c1ob06052j","volume":"9","author":"Antunes","year":"2011","journal-title":"Organic & biomolecular chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/1477-0520","issn-type":"print"},{"key":"34_46530659","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1002\/jhet.5570370203","volume":"37","year":"2000","ISSN":"https:\/\/id.crossref.org\/issn\/0022-152X","issn-type":"print"},{"issue":"3","key":"36_11265769","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1080\/109158101317097728","volume":"20","author":"Miller","year":"2001","journal-title":"International Journal of Toxicology","ISSN":"https:\/\/id.crossref.org\/issn\/1091-5818","issn-type":"print"},{"key":"37_32295783","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/S0074-7742(08)00001-9","volume":"83","author":"Anderson","year":"2008","journal-title":"International review of neurobiology","ISSN":"https:\/\/id.crossref.org\/issn\/0074-7742","issn-type":"print"},{"issue":"2","key":"38_29268930","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1016\/S1550-8579(07)80025-8","volume":"4","author":"Ofotokun","year":"2007","ISSN":"https:\/\/id.crossref.org\/issn\/1550-8579","issn-type":"print"},{"issue":"2","key":"39_22423703","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1517\/17425255.2.2.273","volume":"2","author":"Umeh","year":"2006","ISSN":"https:\/\/id.crossref.org\/issn\/1742-5255","issn-type":"print"},{"issue":"3-4","key":"40_31741053","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1016\/j.phrs.2008.07.007","volume":"58","author":"Floridia","year":"2008","journal-title":"Pharmacological research : the official journal of the Italian Pharmacological Society","ISSN":"https:\/\/id.crossref.org\/issn\/1043-6618","issn-type":"print"},{"issue":"4","key":"41_17294652","doi-asserted-by":"publisher","first-page":"378","DOI":"10.1046\/j.1365-2125.2002.01657.x","volume":"54","author":"de Maat","year":"2002","journal-title":"British journal of clinical pharmacology","ISSN":"https:\/\/id.crossref.org\/issn\/0306-5251","issn-type":"print"},{"issue":"6","key":"42_39546598","doi-asserted-by":"publisher","first-page":"1332","DOI":"10.1093\/jac\/dkr087","volume":"66","year":"2011","journal-title":"Journal of Antimicrobial Chemotherapy","ISSN":"https:\/\/id.crossref.org\/issn\/0305-7453","issn-type":"print"},{"issue":"1","key":"43_30507503","doi-asserted-by":"publisher","first-page":"65","DOI":"10.2174\/157016208783571946","volume":"6","author":"Kiertiburanakul","year":"2008","journal-title":"Current HIV research","ISSN":"https:\/\/id.crossref.org\/issn\/1570-162X","issn-type":"print"},{"issue":"4","key":"44_30454943","doi-asserted-by":"publisher","first-page":"914","DOI":"10.1093\/jac\/dkn029","volume":"61","year":"2008","journal-title":"Journal of Antimicrobial Chemotherapy","ISSN":"https:\/\/id.crossref.org\/issn\/0305-7453","issn-type":"print"},{"issue":"5","key":"45_18282108","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1007\/s00228-004-0769-5","volume":"60","author":"Dailly","year":"2004","journal-title":"European journal of clinical pharmacology","ISSN":"https:\/\/id.crossref.org\/issn\/0031-6970","issn-type":"print"},{"key":"46_46530661","doi-asserted-by":"crossref","first-page":"266","DOI":"10.2174\/1874613601206010266","volume":"6","year":"2012","ISSN":"https:\/\/id.crossref.org\/issn\/1874-6136","issn-type":"print"},{"issue":"5","key":"47_31859979","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1177\/135965350801300507","volume":"13","author":"Stohr","year":"2008","journal-title":"Antiviral therapy","ISSN":"https:\/\/id.crossref.org\/issn\/1359-6535","issn-type":"print"},{"issue":"4","key":"49_31252849","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1517\/17425255.4.4.413","volume":"4","author":"Scandlyn","year":"2008","ISSN":"https:\/\/id.crossref.org\/issn\/1742-5255","issn-type":"print"},{"issue":"5","key":"50_31641786","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1177\/0960327107082224","volume":"27","author":"Sinues","year":"2008","journal-title":"Human and Experimental Toxicology","ISSN":"https:\/\/id.crossref.org\/issn\/0960-3271","issn-type":"print"},{"issue":"11","key":"51_40629715","doi-asserted-by":"publisher","first-page":"721","DOI":"10.1097\/FPC.0b013e32834a522e","volume":"21","author":"Lehr","year":"2011","ISSN":"https:\/\/id.crossref.org\/issn\/1744-6872","issn-type":"print"},{"issue":"7","key":"53_31427294","doi-asserted-by":"publisher","first-page":"1443","DOI":"10.1021\/tx8000972","volume":"21","author":"Antunes","year":"2008","journal-title":"Chemical research in toxicology","ISSN":"https:\/\/id.crossref.org\/issn\/0893-228X","issn-type":"print"},{"key":"54_46530663","doi-asserted-by":"crossref","first-page":"4955","DOI":"10.3390\/molecules18054955","volume":"18","year":"2013","journal-title":"Molecules (Basel, Switzerland)","ISSN":"https:\/\/id.crossref.org\/issn\/1420-3049","issn-type":"print"},{"issue":"1","key":"55_17991371","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1007\/s00210-003-0826-0","volume":"369","author":"Glatt","year":"2004","journal-title":"Naunyn-Schmiedeberg's archives of pharmacology","ISSN":"https:\/\/id.crossref.org\/issn\/0028-1298","issn-type":"print"},{"issue":"3","key":"56_42964941","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1124\/pr.111.005553","volume":"64","author":"Michaud","year":"2012","journal-title":"Pharmacological Reviews","ISSN":"https:\/\/id.crossref.org\/issn\/0031-6997","issn-type":"print"},{"issue":"6","key":"57_21692638","doi-asserted-by":"publisher","first-page":"2084","DOI":"10.1124\/mol.105.019240","volume":"69","year":"2006","journal-title":"Molecular Pharmacology","ISSN":"https:\/\/id.crossref.org\/issn\/0026-895X","issn-type":"print"},{"issue":"3","key":"58_38934551","doi-asserted-by":"publisher","first-page":"187","DOI":"10.3109\/00498254.2010.535923","volume":"41","author":"Alnouti","year":"2011","journal-title":"Xenobiotica; the fate of foreign compounds in biological systems","ISSN":"https:\/\/id.crossref.org\/issn\/0049-8254","issn-type":"print"},{"issue":"2","key":"59_22330094","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1093\/toxsci\/kfl050","volume":"93","year":"2006","journal-title":"Toxicological Sciences","ISSN":"https:\/\/id.crossref.org\/issn\/1096-6080","issn-type":"print"},{"issue":"1-2","key":"60_43410024","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1016\/j.mrgentox.2012.07.002","volume":"749","author":"Suzuki","year":"2012","journal-title":"Mutation Research","ISSN":"https:\/\/id.crossref.org\/issn\/0027-5107","issn-type":"print"},{"issue":"Pt 3","key":"61_11181317","doi-asserted-by":"publisher","first-page":"891","DOI":"10.1042\/0264-6021:3560891","volume":"356","author":"Tsoi","year":"2001","journal-title":"The Biochemical journal","ISSN":"https:\/\/id.crossref.org\/issn\/0264-6021","issn-type":"print"},{"issue":"3","key":"62_11068239","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1016\/S0378-4274(01)00263-6","volume":"119","author":"Wu","year":"2001","journal-title":"Toxicology letters","ISSN":"https:\/\/id.crossref.org\/issn\/0378-4274","issn-type":"print"},{"issue":"1","key":"63_16450789","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/S0022-3565(25)20978-8","volume":"279","author":"Liu","year":"1996","journal-title":"Journal of Pharmacology and Experimental Therapeutics","ISSN":"https:\/\/id.crossref.org\/issn\/0022-3565","issn-type":"print"},{"issue":"6","key":"64_6033434","first-page":"598","volume":"26","author":"Dunn II","year":"1998","journal-title":"Drug Metabolism and Disposition","ISSN":"https:\/\/id.crossref.org\/issn\/0090-9556","issn-type":"print"},{"key":"65_46530664","doi-asserted-by":"crossref","first-page":"15","DOI":"10.3109\/03602532.2012.748794","volume":"45","year":"2013","journal-title":"Drug metabolism reviews","ISSN":"https:\/\/id.crossref.org\/issn\/0360-2532","issn-type":"print"},{"key":"66_46530665","first-page":"387","volume":"214","year":"2012","journal-title":"HANDBK EXP PHARMACOL"},{"issue":"12","key":"67_38031224","doi-asserted-by":"publisher","first-page":"2204","DOI":"10.1124\/dmd.110.035345","volume":"38","year":"2010","journal-title":"Drug Metabolism and Disposition","ISSN":"https:\/\/id.crossref.org\/issn\/0090-9556","issn-type":"print"},{"issue":"Pt 2","key":"68_17128305","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1042\/BJ20020044","volume":"365","author":"Fuda","year":"2002","journal-title":"The Biochemical journal","ISSN":"https:\/\/id.crossref.org\/issn\/0264-6021","issn-type":"print"},{"issue":"1","key":"69_11463234","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1097\/00008571-200201000-00003","volume":"12","author":"Xu","year":"2002","journal-title":"Pharmacogenetics","ISSN":"https:\/\/id.crossref.org\/issn\/0960-314X","issn-type":"print"},{"issue":"11","key":"70_17654257","doi-asserted-by":"publisher","first-page":"1787","DOI":"10.1016\/S0006-2952(03)00421-0","volume":"65","author":"Xu","year":"2003","journal-title":"Biochemical pharmacology","ISSN":"https:\/\/id.crossref.org\/issn\/0006-2952","issn-type":"print"},{"issue":"1","key":"71_17601986","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/1521654031000072148","volume":"55","author":"Venkatachalam","year":"2003","journal-title":"IUBMB life","ISSN":"https:\/\/id.crossref.org\/issn\/1521-6543","issn-type":"print"},{"issue":"1","key":"72_39095930","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/2042-6410-2-1","volume":"2","author":"Voskuhl","year":"2011","ISSN":"https:\/\/id.crossref.org\/issn\/2042-6410","issn-type":"print"}],"container-title":["Journal of Antimicrobial Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jac\/article-pdf\/69\/2\/476\/2100449\/dkt359.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T14:47:01Z","timestamp":1746024421000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jac\/article-lookup\/doi\/10.1093\/jac\/dkt359"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9,19]]},"references-count":66,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2014,1,9]]},"published-print":{"date-parts":[[2014,2,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jac\/dkt359","relation":{},"ISSN":["0305-7453","1460-2091"],"issn-type":[{"value":"0305-7453","type":"print"},{"value":"1460-2091","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,9,19]]}}}