{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T14:03:44Z","timestamp":1773065024429,"version":"3.50.1"},"reference-count":27,"publisher":"Oxford University Press (OUP)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,11]]},"DOI":"10.1093\/mollus\/eys018","type":"journal-article","created":{"date-parts":[[2012,9,26]],"date-time":"2012-09-26T08:33:55Z","timestamp":1348648435000},"page":"343-348","source":"Crossref","is-referenced-by-count":5,"title":["Molecular characterization of Adh3 from the mollusc Nucella lapillus: tissue gene expression after tributyltin and retinol exposure"],"prefix":"10.1093","volume":"78","author":[{"given":"In\u00eas","family":"Coelho","sequence":"first","affiliation":[]},{"given":"Daniela","family":"Lima","sequence":"additional","affiliation":[]},{"given":"Ana","family":"Andr\u00e9","sequence":"additional","affiliation":[]},{"given":"Carlos","family":"Melo","sequence":"additional","affiliation":[]},{"given":"Raquel","family":"Ruivo","sequence":"additional","affiliation":[]},{"given":"Maria Armanda","family":"Reis-Henriques","sequence":"additional","affiliation":[]},{"given":"Miguel Machado","family":"Santos","sequence":"additional","affiliation":[]},{"given":"Lu\u00eds Filipe Costa","family":"Castro","sequence":"additional","affiliation":[]}],"member":"286","published-online":{"date-parts":[[2012,9,25]]},"reference":[{"key":"key\n\t\t\t\t20170721010602_EYS018C1","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.cbi.2008.09.017","article-title":"Identification of Aldh1a, Cyp26 and RAR orthologs in protostomes pushes back the retinoic acid genetic machinery in evolutionary time to the bilaterian ancestor","volume":"178","author":"ALBALAT","year":"2009","journal-title":"Chemical-Biological Interactions"},{"key":"key\n\t\t\t\t20170721010602_EYS018C2","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/j.envint.2007.09.005","article-title":"Environmental levels, toxicity and human exposure to tributyltin (TBT)-contaminated marine environment. A review","volume":"34","author":"ANTIZAR-LADISLAO","year":"2008","journal-title":"Environmental International"},{"key":"key\n\t\t\t\t20170721010602_EYS018C3","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/j.marenvres.2004.03.042","article-title":"A cDNA microarray technique applied for analysis of global gene expression profiles in tributyltin-exposed ascidians","volume":"58","author":"AZUMI","year":"2004","journal-title":"Marine Environmental Research"},{"key":"key\n\t\t\t\t20170721010602_EYS018C4","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1007\/BF02367105","article-title":"TBT-induced imposex in marine neogastropods is mediated by an increasing androgen level","volume":"50","author":"BETTIN","year":"1996","journal-title":"Helgol\u00e4nder Meeresuntersuchungen"},{"key":"key\n\t\t\t\t20170721010602_EYS018C5","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1093\/toxsci\/kfn030","article-title":"Fifteen years after \u201cWingspread\u201d environmental endocrine disrupters and human and wildlife health: where we are today and where we need to go","volume":"105","author":"BLYSTONE","year":"2008","journal-title":"Toxicological Science"},{"key":"key\n\t\t\t\t20170721010602_EYS018C6","doi-asserted-by":"crossref","first-page":"128","DOI":"10.2108\/zsj.27.128","article-title":"Oikopleura dioica alcohol dehydrogenase class 3 provides new insights into the evolution of retinoic acid synthesis in chordates","volume":"27","author":"CA\u00d1ESTRO","year":"2010","journal-title":"Zoological Science"},{"key":"key\n\t\t\t\t20170721010602_EYS018C7","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1046\/j.1525-142X.2003.03022.x","article-title":"Comparative expression analysis of Adh3 during arthropod, urochordate, cephalochordate, and vertebrate development challenges its predicted housekeeping role","volume":"5","author":"CA\u00d1ESTRO","year":"2003","journal-title":"Evolution and Development"},{"key":"key\n\t\t\t\t20170721010602_EYS018C8","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.aquatox.2007.07.016","article-title":"Imposex induction is mediated through the Retinoid X Receptor signalling pathway in the neogastropod Nucella lapillus","volume":"85","author":"CASTRO","year":"2007","journal-title":"Aquatic Toxicology"},{"key":"key\n\t\t\t\t20170721010602_EYS018C9","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1111\/j.1440-169X.1993.00357.x","article-title":"Specific developmental defects in molluscs after treatment with retinoic acid during gastrulation","volume":"35","author":"CR\u00c9TON","year":"1993","journal-title":"Development, Growth & Differentiation"},{"key":"key\n\t\t\t\t20170721010602_EYS018C10","article-title":"Endocrine disruption in invertebrates: endocrinology, testing, and assessment","volume-title":"Proceedings of the workshops on endocrine disruption in invertebrates","author":"DEFUR","year":"1999"},{"key":"key\n\t\t\t\t20170721010602_EYS018C11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3109\/10408449609089891","article-title":"Ecotoxicology of organotin compounds","volume":"26","author":"FENT","year":"1996","journal-title":"Critical Reviews in Toxicology"},{"key":"key\n\t\t\t\t20170721010602_EYS018C12","doi-asserted-by":"crossref","first-page":"e35138","DOI":"10.1371\/journal.pone.0035138","article-title":"Retinol metabolism in the mollusk Osilinus lineatus indicates an ancient origin for retinyl ester storage capacity","volume":"7","author":"GESTO","year":"2012","journal-title":"PLoS ONE"},{"key":"key\n\t\t\t\t20170721010602_EYS018C13","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1017\/S0025315400048414","article-title":"Reproductive failure in populations of the dog-whelk, Nucella lapillus, caused by imposex induced by tributyltin from antifouling paints","volume":"66","author":"GIBBS","year":"1986","journal-title":"Journal of the Marine Biological Association of the United Kingdom"},{"key":"key\n\t\t\t\t20170721010602_EYS018C14","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1017\/S0025315400027260","article-title":"The use of dogwhelk (Nucella lapillus) as an indicator of TBT contamination","volume":"67","author":"GIBBS","year":"1987","journal-title":"Journal of the Marine Biological Association of the United Kingdom"},{"key":"key\n\t\t\t\t20170721010602_EYS018C15","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.cbpb.2006.11.007","article-title":"Analysis of planarian Adh3 supports an intron-rich architecture and tissue-specific expression for the urbilaterian ancestral form","volume":"146","author":"GODOY","year":"2007","journal-title":"Comparative Biochemistry and Physiology\u2014Part B: Biochemistry & Molecular Biology"},{"key":"key\n\t\t\t\t20170721010602_EYS018C16","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1038\/sj.hdy.6800723","article-title":"Merging protein, gene and genomic data: the evolution of the MDR-ADH family","volume":"95","author":"GONZ\u00c0LEZ-DUARTE","year":"2005","journal-title":"Heredity"},{"key":"key\n\t\t\t\t20170721010602_EYS018C17","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1124\/mol.104.008409","article-title":"Organotin compounds promote adipocyte DIFFERENTIATION as agonists of the peroxisome proliferator-activated receptor gamma\/retinoid X receptor pathway","volume":"67","author":"KANAYAMA","year":"2005","journal-title":"Molecular Pharmacology"},{"key":"key\n\t\t\t\t20170721010602_EYS018C18","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.aquatox.2010.09.022","article-title":"Tributyltin-induced imposex in marine gastropods involves tissue-specific modulation of the retinoid X receptor","volume":"101","author":"LIMA","year":"2011","journal-title":"Aquatic Toxicology"},{"key":"key\n\t\t\t\t20170721010602_EYS018C19","doi-asserted-by":"crossref","first-page":"5337","DOI":"10.1073\/pnas.082093299","article-title":"Stimulation of retinoic acid production and growth by ubiquitously expressed alcohol dehydrogenase Adh3","volume":"99","author":"MOLOTKOV","year":"2002","journal-title":"Proceedings of the National Academy of Sciences of the USA"},{"key":"key\n\t\t\t\t20170721010602_EYS018C20","doi-asserted-by":"crossref","first-page":"269","DOI":"10.2131\/jts.33.269","article-title":"Endocrine disruption induced by organotin compounds; organotins function as a powerful agonist for nuclear receptors rather than an aromatase inhibitor","volume":"33","author":"NAKANISHI","year":"2008","journal-title":"Journal of Toxicological Sciences"},{"key":"key\n\t\t\t\t20170721010602_EYS018C21","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1007\/s00227-005-0210-3","article-title":"Imposex in marine gastropods may be caused by binding of organotins to retinoid X receptor","volume":"149","author":"NISHIKAWA","year":"2006","journal-title":"Marine Biology"},{"key":"key\n\t\t\t\t20170721010602_EYS018C22","doi-asserted-by":"crossref","first-page":"6271","DOI":"10.1021\/es049593u","article-title":"Involvement of the retinoid X receptor in the development of imposex caused by organotins in gastropods","volume":"38","author":"NISHIKAWA","year":"2004","journal-title":"Environmental Science and Technology"},{"key":"key\n\t\t\t\t20170721010602_EYS018C23","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/j.chemosphere.2008.12.066","article-title":"Organotin levels in seafood from Portuguese markets and the risk for consumers","volume":"75","author":"SANTOS","year":"2009","journal-title":"Chemosphere"},{"key":"key\n\t\t\t\t20170721010602_EYS018C24","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1007\/s10646-009-0397-z","article-title":"Environmental-endocrine control of reproductive maturation in gastropods: implications for the mechanism of tributyltin-induced imposex in prosobranchs","volume":"19","author":"STERNBERG","year":"2010","journal-title":"Ecotoxicology"},{"key":"key\n\t\t\t\t20170721010602_EYS018C25","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1021\/es702381g","article-title":"Synchronized expression of retinoid X receptor mRNA with reproductive tract recrudescence in an imposex-susceptible mollusc","volume":"42","author":"STERNBERG","year":"2008","journal-title":"Environmental Science and Technology"},{"key":"key\n\t\t\t\t20170721010602_EYS018C26","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1002\/aheh.200400555","article-title":"Endocrine disrupters in the aquatic environment: an overview","volume":"33","author":"SUMPTER","year":"2005","journal-title":"Acta Hydrochimica et Hydrobiologica"},{"key":"key\n\t\t\t\t20170721010602_EYS018C27","doi-asserted-by":"crossref","first-page":"10868","DOI":"10.1074\/jbc.270.18.10868","article-title":"Cloning of the mouse class IV alcohol dehydrogenase (retinol dehydrogenase) cDNA and tissue-specific expression patterns of the murine ADH gene family","volume":"270","author":"ZGOMBI\u0106-KNIGHT","year":"1995","journal-title":"Journal of Biological Chemistry"}],"container-title":["Journal of Molluscan Studies"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/mollus\/article-pdf\/78\/4\/343\/18790214\/eys018.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,8,23]],"date-time":"2017-08-23T19:13:11Z","timestamp":1503515591000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/mollus\/article-lookup\/doi\/10.1093\/mollus\/eys018"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,9,25]]},"references-count":27,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2012,9,25]]},"published-print":{"date-parts":[[2012,11]]}},"URL":"https:\/\/doi.org\/10.1093\/mollus\/eys018","relation":{},"ISSN":["0260-1230","1464-3766"],"issn-type":[{"value":"0260-1230","type":"print"},{"value":"1464-3766","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,9,25]]}}}