{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T17:50:41Z","timestamp":1775065841207,"version":"3.50.1"},"reference-count":40,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2020,5,26]],"date-time":"2020-05-26T00:00:00Z","timestamp":1590451200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Healthway Health Promotion Foundation of Western Australia","award":["6018 1998 2000"],"award-info":[{"award-number":["6018 1998 2000"]}]},{"name":"National Health and Medical Research Council of Australia","award":["254627"],"award-info":[{"award-number":["254627"]}]},{"name":"National Health and Medical Research Council of Australia","award":["303169"],"award-info":[{"award-number":["303169"]}]},{"name":"Fond de Recherche du Qu\u00e9bec en Sant\u00e9","award":["#35837"],"award-info":[{"award-number":["#35837"]}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["GNT1151246"],"award-info":[{"award-number":["GNT1151246"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,8,27]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Many older women demonstrate an age-related accelerating rate of renal decline that is associated with increased rates of bone disease, cardiovascular disease and mortality. Population-based protein restriction has been studied principally in patients with reduced renal function. In this investigation, we examined the hypothesis of a differential effect of plant-derived protein compared with animal-derived protein on renal function in older women.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We assessed dietary intake from a validated food frequency questionnaire and the estimated glomerular filtration rate (eGFR) (using the Chronic Kidney Disease Epidemiology Collaboration creatinine and cystatin C equation) at baseline, 5 and 10\u2009years in the Longitudinal Study of Aging Women cohort. We tested the association between plant- and animal-sourced protein intake and kidney function using linear mixed modeling.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A total of 1374 Caucasian women [mean (standard deviation, SD) age\u2009=\u200975\u2009years (2.7) and mean (SD) baseline eGFR\u2009=\u200965.6\u2009mL\/min\/1.73\u2009m2 (13.1)] contributed to the analysis. The average decline in eGFR was 0.64\u2009mL\/min\/1.73\u2009m2\/year [95% confidence interval (CI) 0.56\u20130.72]. Higher intakes of plant-sourced protein were associated with slower declines in eGFR after adjusting for covariates including animal protein and energy intake (P\u2009=\u20090.03). For each 10\u2009g of plant protein, the yearly decline in eGFR was reduced by 0.12\u2009mL\/min\/1.73\u2009m2 (95% CI 0.01\u20130.23), principally associated with fruit-, vegetable- and nut-derived protein. The intake of animal protein was not associated with eGFR decline (P\u2009=\u20090.84).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Older women consuming a diet that is richer in plant-sourced protein have a slower decline in kidney function. These data extend support for the health benefits of plant-rich diets in the general population to maintain kidney health.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ndt\/gfaa081","type":"journal-article","created":{"date-parts":[[2020,3,26]],"date-time":"2020-03-26T12:09:57Z","timestamp":1585224597000},"page":"1640-1647","source":"Crossref","is-referenced-by-count":39,"title":["Dietary plant and animal protein intake and decline in estimated glomerular filtration rate among elderly women: a 10-year longitudinal cohort study"],"prefix":"10.1093","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2357-6876","authenticated-orcid":false,"given":"Am\u00e9lie","family":"Bernier-Jean","sequence":"first","affiliation":[{"name":"Centre for Kidney Research, Children\u2019s Hospital at Westmead, School of Public Health, Sydney Medical School, The University of Sydney, Sydney, Australia"}]},{"given":"Richard L","family":"Prince","sequence":"additional","affiliation":[{"name":"Medical School, University of Western Australia, Perth, Australia"},{"name":"Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Perth, Australia"}]},{"given":"Joshua R","family":"Lewis","sequence":"additional","affiliation":[{"name":"Centre for Kidney Research, Children\u2019s Hospital at Westmead, School of Public Health, Sydney Medical School, The University of Sydney, Sydney, Australia"},{"name":"Medical School, University of Western Australia, Perth, Australia"},{"name":"School of Medical and Health Sciences, Edith Cowan University, Joondalup, Australia"}]},{"given":"Jonathan C","family":"Craig","sequence":"additional","affiliation":[{"name":"College of Medicine and Public Health, Flinders University, Adelaide, Australia"}]},{"given":"Jonathan M","family":"Hodgson","sequence":"additional","affiliation":[{"name":"Medical School, University of Western Australia, Perth, Australia"},{"name":"School of Medical and Health Sciences, Edith Cowan University, Joondalup, Australia"}]},{"given":"Wai H","family":"Lim","sequence":"additional","affiliation":[{"name":"Medical School, University of Western Australia, Perth, Australia"},{"name":"Department of Renal Medicine, Sir Charles Gairdner Hospital, Perth, Australia"}]},{"given":"Armando","family":"Teixeira-Pinto","sequence":"additional","affiliation":[{"name":"Centre for Kidney Research, Children\u2019s Hospital at Westmead, School of Public Health, Sydney Medical School, The University of Sydney, Sydney, Australia"}]},{"given":"Germaine","family":"Wong","sequence":"additional","affiliation":[{"name":"Centre for Kidney Research, Children\u2019s Hospital at Westmead, School of Public Health, Sydney Medical School, The University of Sydney, Sydney, 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