{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T11:20:11Z","timestamp":1762082411387,"version":"build-2065373602"},"reference-count":70,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001862","name":"FORMAS","doi-asserted-by":"crossref","award":["215-2012-1319"],"award-info":[{"award-number":["215-2012-1319"]}],"id":[{"id":"10.13039\/501100001862","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100002805","name":"Carl Trygger Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002805","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001725","name":"Royal Swedish Academy of Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001725","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Linnaeus University Centre for Ecology and Evolution in Microbial model Systems"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Vitamin B1 (thiamin) is primarily produced by bacteria, phytoplankton and fungi in aquatic food webs and transferred to higher trophic levels by ingestion. However, much remains unknown regarding the dynamics this water-soluble, essential micronutrient; e.g. how it relates to macronutrients (carbon, nitrogen and phosphorous). Nutrient limitation has been found to be related to periods of thiamin deficiency as well as in models. Hence, thiamin transfer to copepods from three phytoplankton species from different taxa was investigated, along with the effect of various nutrient regimes on thiamin content. Nutrient levels did not affect thiamin content of phytoplankton nor the transfer to copepods. Instead, phytoplankton displayed species-specific thiamin and macronutrient contents and whilst a higher thiamin content in the prey lead to higher levels in copepods, the transfer was lower for Skeletonema compared to Dunaliella and Rhodomonas. In all, thiamin transfer to copepods is not only dependent on thiamin content of the prey, but also the edibility and\/or digestibility is of importance. Thiamin is essential for all organisms, and this study offers insights into the limited effect of macronutrients on the dynamics and transfer of thiamin in the aquatic food webs.<\/jats:p>","DOI":"10.1093\/plankt\/fbad004","type":"journal-article","created":{"date-parts":[[2023,2,2]],"date-time":"2023-02-02T00:56:18Z","timestamp":1675299378000},"page":"360-371","source":"Crossref","is-referenced-by-count":3,"title":["Limited effects of macro-nutrient ratios on thiamin content and transfer in phytoplankton and copepods"],"prefix":"10.1093","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4871-7441","authenticated-orcid":false,"given":"Emil","family":"Fridolfsson","sequence":"first","affiliation":[{"name":"Department of Biology and Environmental Sciences , Centre for Ecology and Evolution in Microbial model Systems \u2013 EEMiS, , Kalmar SE-39182 , Sweden"},{"name":"Linnaeus University , Centre for Ecology and Evolution in Microbial model Systems \u2013 EEMiS, , Kalmar SE-39182 , Sweden"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0183-2314","authenticated-orcid":false,"given":"Sanna","family":"Majaneva","sequence":"additional","affiliation":[{"name":"Department of Biology and Environmental Sciences , Centre for Ecology and Evolution in Microbial model Systems \u2013 EEMiS, , Kalmar SE-39182 , Sweden"},{"name":"Linnaeus University , Centre for Ecology and Evolution in Microbial model Systems \u2013 EEMiS, , Kalmar SE-39182 , Sweden"},{"name":"Norwegian University of Science and Technology, Department of Biology \/ Trondhjem Biological Station , Trondheim NO-7491 , Norway"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3740-5998","authenticated-orcid":false,"given":"Samuel","family":"Hylander","sequence":"additional","affiliation":[{"name":"Department of Biology and Environmental Sciences , Centre for Ecology and Evolution in Microbial model Systems \u2013 EEMiS, , Kalmar SE-39182 , Sweden"},{"name":"Linnaeus University , Centre for Ecology and Evolution in Microbial model Systems \u2013 EEMiS, , Kalmar SE-39182 , Sweden"}]}],"member":"286","published-online":{"date-parts":[[2023,2,1]]},"reference":[{"volume-title":"Algal Culturing Techniques","year":"2005","author":"Andersen","key":"2023040123201945200_"},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1007\/BF00351346","article-title":"Succession and growth limitation of phytoplankton in the Gulf of Bothnia (Baltic Sea)","volume":"126","author":"Andersson","year":"1996","journal-title":"Mar. Biol."},{"key":"2023040123201945200_","article-title":"gridExtra: miscellaneous functions for \"grid\" graphics","author":"Auguie","year":"2017","journal-title":"R package version 2.3 ed"},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"12001","DOI":"10.1073\/pnas.0902903106","article-title":"Wild birds of declining European species are dying from a thiamine deficiency syndrome","volume":"106","author":"Balk","year":"2009","journal-title":"PNAS"},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"38821","DOI":"10.1038\/srep38821","article-title":"Widespread episodic thiamine deficiency in northern hemisphere wildlife","volume":"6","author":"Balk","year":"2016","journal-title":"Sci. Rep."},{"key":"2023040123201945200_","first-page":"2","article-title":"Reproductive disturbances in Baltic fish: a synopsis of the FiRe project","volume":"28","author":"Bengtsson","year":"1999","journal-title":"Ambio"},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1046\/j.1529-8817.2001.01052.x","article-title":"Evolution of an artificial seawater medium: improvements in enriched seawater, artificial water over the last two decades","volume":"37","author":"Berges","year":"2001","journal-title":"J. Phycol."},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1002\/iroh.200811066","article-title":"Nutritional limitation travels up the food chain","volume":"93","author":"Boersma","year":"2008","journal-title":"Internat Rev Hydrobiol"},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1023\/A:1020395526898","article-title":"Some ecological properties in relation to eutrophication in the Baltic Sea","volume":"475\/476","author":"Bonsdorff","year":"2002","journal-title":"Hydrobiologia"},{"key":"2023040123201945200_","first-page":"1","volume-title":"Redovisning Av M74-f\u00f6rekomsten i svenska kompensationsodlade laxstammar fr\u00e5n \u00d6stersj\u00f6n f\u00f6r 2016","author":"B\u00f6rjesson","year":"2016"},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1046\/j.1365-2427.1997.00220.x","article-title":"The role of highly unsaturated fatty acids in aquatic foodweb processes","volume":"38","author":"Brett","year":"1997","journal-title":"Freshw. Biol."},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1023\/A:1008075903578","article-title":"The vitamin content of microalgae used in aquaculture","volume":"11","author":"Brown","year":"1999","journal-title":"J. Appl. Phycol."},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1111\/j.1529-8817.1970.tb02406.x","article-title":"Production of vitamin B12, thiamine and biotin by phytoplankton","volume":"6","author":"Carlucci","year":"1970","journal-title":"J. Phycol."},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1073\/pnas.0806649105","article-title":"Trophic cascades promote threshold-like shifts in pelagic marine ecosystems","volume":"106","author":"Casini","year":"2009","journal-title":"PNAS"},{"volume-title":"The Vitamins","year":"2012","author":"Combs","key":"2023040123201945200_"},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1128\/EC.00097-06","article-title":"Algae need their vitamins","volume":"5","author":"Croft","year":"2006","journal-title":"Eukaryot. Cell"},{"key":"2023040123201945200_","first-page":"323","article-title":"Requirement for thiamine among some marine and supra-Littoral Protista","volume-title":"J Mar Biol Assoc","author":"Droop","year":"1958"},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"10045","DOI":"10.1038\/s41598-019-46422-2","article-title":"Modeling vitamin B1 transfer to consumers in the aquatic food web","volume":"9","author":"Ejsmond","year":"2019","journal-title":"Sci. Rep."},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"e0227201","DOI":"10.1371\/journal.pone.0227201","article-title":"Severe thiamine deficiency in eastern Baltic cod (Gadus morhua)","volume":"15","author":"Engelhardt","year":"2020","journal-title":"PLoS One"},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1577\/1548-8667(1995)007<0269:PABMOT>2.3.CO;2","article-title":"Pathological and behavioral manifestations of the \"Cayuga syndrome,\" a thiamine deficiency in larval landlocked Atlantic salmon","volume":"7","author":"Fisher","year":"1995","journal-title":"J. Aquat. Anim. Health"},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1007\/s00227-019-3520-6","article-title":"Seasonal variation and species-specific concentrations of the essential vitamin B1 (thiamin) in zooplankton and seston","volume":"166","author":"Fridolfsson","year":"2019","journal-title":"Mar. Biol."},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"2423","DOI":"10.1002\/lno.10949","article-title":"Thiamin (vitamin B1) content in phytoplankton and zooplankton in the presence of filamentous cyanobacteria","volume":"63","author":"Fridolfsson","year":"2018","journal-title":"Limnol. Oceanogr."},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1093\/plankt\/fbaa015","article-title":"Species-specific content of thiamin (vitamin B1) in phytoplankton and the transfer to copepods","volume":"42","author":"Fridolfsson","year":"2020","journal-title":"J. Plankton Res."},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"2809","DOI":"10.1111\/1462-2920.14133","article-title":"Mosaic patterns of B-vitamin synthesis and utilization in a natural marine microbial community","volume":"20","author":"G\u00f3mez-Consarnau","year":"2018","journal-title":"Environ. Microbiol."},{"key":"2023040123201945200_","first-page":"142","article-title":"Nutrient limitation of primary production in the Baltic Sea area","volume":"19","author":"Graneli","year":"1990","journal-title":"Ambio"},{"key":"2023040123201945200_","first-page":"26","volume-title":"Culture of Marine Invertebrates","author":"Guillard","year":"1975"},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"234","DOI":"10.2216\/i0031-8884-32-3-234.1","article-title":"Stichochrysis immobilis is a diatom, not a chrysophyte","volume":"32","author":"Guillard","year":"1993","journal-title":"Phycologia"},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"e01459","DOI":"10.1128\/mBio.01459-17","article-title":"Globally important haptophyte algae use exogenous pyrimidine compounds more efficiently than Thiamin","volume":"8","author":"Gutowska","year":"2017","journal-title":"MBio"},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1086\/285546","article-title":"Cause-effect relationships in energy flow, trophic structure, and interspecific interactions","volume":"142","author":"Hairston","year":"1993","journal-title":"Am. Nat."},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"2219","DOI":"10.4319\/lo.2013.58.6.2219","article-title":"Ecological stoichiometry: an elementary approach using basic principles","volume":"58","author":"Hessen","year":"2013","journal-title":"Limnol. Oceanogr."},{"key":"2023040123201945200_","article-title":"Report of the Baltic Salmon and Trout assessment working group (WGBAST)","volume":"2","author":"ICES","year":"2020","journal-title":"ICES Scientific Reports"},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/BF00349475","article-title":"Effects of food quality on the reproductive success of Acartia tonsa and Acartia hudsonica: laboratory observations","volume":"121","author":"J\u00f3nasd\u00f3ttir","year":"1994","journal-title":"Mar. Biol."},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1146\/annurev.biochem.78.072407.102340","article-title":"The structural and biochemical foundations of thiamin biosynthesis","volume":"78","author":"Jurgenson","year":"2009","journal-title":"Annu. Rev. Biochem."},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"125690","DOI":"10.1016\/j.limno.2019.125690","article-title":"The stoichiometric ratios (C:N:P) in a pelagic food web under experimental conditions","volume":"77","author":"Karpowicz","year":"2019","journal-title":"Limnologica"},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1093\/icesjms\/fss041","article-title":"The thiamine deficiency syndrome M74, a reproductive disorder of Atlantic salmon (Salmo salar) feeding in the Baltic Sea, is related to the fat and thiamine content of prey fish","volume":"69","author":"Kein\u00e4nen","year":"2012","journal-title":"ICES J. Mar. Sci."},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1086\/692168","article-title":"Competition for vitamin B1 (thiamin) structures numerous ecological interactions","volume":"92","author":"Kraft","year":"2017","journal-title":"Q. Rev. Biol."},{"issue":"Suppl 3","key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1007\/s13280-015-0662-8","article-title":"Interannual variability of phyto-bacterioplankton biomass and production in coastal and offshore waters of the Baltic Sea","volume":"44","author":"Legrand","year":"2015","journal-title":"Ambio"},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"189","DOI":"10.4319\/lo.2003.48.1.0189","article-title":"Beyond bulk properties: responses of coastal summer plankton communities to nutrient enrichment in the northern Baltic Sea","volume":"48","author":"Lignell","year":"2003","journal-title":"Limnol. Oceanogr."},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"e0227714","DOI":"10.1371\/journal.pone.0227714","article-title":"Deficiency syndromes in top predators associated with large-scale changes in the Baltic Sea ecosystem","volume":"15","author":"Majaneva","year":"2020","journal-title":"PLoS One"},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"2062","DOI":"10.4319\/lo.2007.52.5.2062","article-title":"Nutrient limitation of primary producers affects planktivorous fish condition","volume":"52","author":"Malzahn","year":"2007","journal-title":"Limnol. Oceanogr."},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1021\/bi401618y","article-title":"Thiamin function, metabolism, uptake, and transport","volume":"53","author":"Manzetti","year":"2014","journal-title":"Biochemistry"},{"key":"2023040123201945200_","first-page":"135","volume-title":"Chemically Induced Alterations in Functional Development and Reproduction of Fishes","author":"Marcquenski","year":"1997"},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"2134","DOI":"10.1093\/icesjms\/fsr156","article-title":"Relationships between fish stock changes in the Baltic Sea and the M74 syndrome, a reproductive disorder of Atlantic salmon (Salmo salar)","volume":"68","author":"Mikkonen","year":"2011","journal-title":"ICES J. Mar. Sci."},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1093\/plankt\/fbi022","article-title":"Predator\u2013prey interactions: is \u2018ecological stoichiometry\u2019 sufficient when good food goes bad?","volume":"27","author":"Mitra","year":"2005","journal-title":"J. Plankton Res."},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1093\/icesjms\/fsm197","article-title":"Effects of climate and overfishing on zooplankton dynamics and ecosystem structure: regime shifts, trophic cascade, and feedback loops in a simple ecosystem","volume":"65","author":"M\u00f6llmann","year":"2008","journal-title":"ICES J. Mar. Sci."},{"key":"2023040123201945200_","first-page":"235","article-title":"The functional role of planktonic mixotrophs in altering seston stoichiometry","volume-title":"Aquat Microb Ecol","author":"Moorthi","year":"2017"},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"15","DOI":"10.3354\/meps266015","article-title":"Phosphorus dynamics during the transition from nitrogen to phosphate limitation in the Central Baltic Sea","volume":"266","author":"Nausch","year":"2004","journal-title":"Mar. Ecol. Prog. Ser."},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"77","DOI":"10.3354\/meps221077","article-title":"Zooplankton growth, diet and reproductive success compared in simultaneous diatom- and flagellate-microzooplankton-dominated plankton blooms","volume":"221","author":"Nejstgaard","year":"2001","journal-title":"Mar Ecol Progr Ser"},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"5940","DOI":"10.1038\/s41598-018-24321-2","article-title":"Carboxythiazole is a key microbial nutrient currency and critical component of thiamin biosynthesis","volume":"8","author":"Paerl","year":"2018","journal-title":"Sci. Rep."},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"E10447","DOI":"10.1073\/pnas.1806425115","article-title":"Prevalent reliance of bacterioplankton on exogenous vitamin B1 and precursor availability","volume":"115","author":"Paerl","year":"2018","journal-title":"PNAS"},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1111\/j.1600-0706.2009.18545.x","article-title":"To be or not to be what you eat: regulation of stoichiometric homeostasis among autotrophs and heterotrophs","volume":"119","author":"Persson","year":"2010","journal-title":"Oikos"},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1006\/bbrc.2002.6438","article-title":"Simultaneous detection of thiamine and its phosphate esters from microalgae by HPLC","volume":"291","author":"Pinto","year":"2002","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"283","DOI":"10.3354\/meps129283","article-title":"Nitrogen and phosphorus as production limiting factors in the estuarine waters of the eastern gulf of Finland","volume":"129","author":"Pitk\u00e4nen","year":"1995","journal-title":"Mar Ecol Progr Ser"},{"key":"2023040123201945200_","first-page":"49","article-title":"Phytoplankton composition in Dutch coastal waters responds to changes in riverine nutrient loads","volume-title":"J Sea Res","author":"Prins","year":"2012"},{"volume-title":"R: A Language and Environment for Statistical Computing","year":"2019","author":"R Core Team","key":"2023040123201945200_"},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1111\/j.1529-8817.1980.tb03065.x","article-title":"Optimum N:P ratios and coexistence of planktonic algae","volume":"16","author":"Rhee","year":"1980","journal-title":"J. Phycol."},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1577\/T06-210.1","article-title":"Phylogenetic and ecological characteristics associated with thiaminase activity in Laurentian Great Lakes fishes","volume":"137","author":"Riley","year":"2008","journal-title":"Trans. Am. Fish. Soc."},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1146\/annurev-marine-120710-100912","article-title":"The role of B vitamins in marine biogeochemistry","volume":"6","author":"Sa\u00f1udo-Wilhelmy","year":"2014","journal-title":"Annu. Rev. Mar. Sci."},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"e0050321","DOI":"10.1128\/jb.00503-21","article-title":"Exchange of vitamin B1 and its biosynthesis intermediates shapes the composition of synthetic microbial cocultures and reveals complexities of nutrient sharing","volume":"204","author":"Sathe","year":"2022","journal-title":"J. Bacteriol."},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"754","DOI":"10.4319\/lo.1980.25.4.0754","article-title":"Determination of total dissolved phosphorus and particulate phosphorus in natural waters1","volume":"25","author":"Sol\u00f3rzano","year":"1980","journal-title":"Limnol. Oceanogr."},{"volume-title":"Water Quality - Determination of Phosphorus - Ammonium Molybdate Spectrometric Method (ISO 6878:2004)","year":"2005","author":"SS-EN ISO 6878:2005","key":"2023040123201945200_"},{"volume-title":"Ecological stoichiometry: the biology of elements from molecules to the biosphere","year":"2002","author":"Sterner","key":"2023040123201945200_"},{"key":"2023040123201945200_","doi-asserted-by":"crossref","DOI":"10.3389\/fmars.2020.606342","article-title":"Exploring vitamin B1 cycling and its connections to the microbial Community in the North Atlantic Ocean","volume":"7","author":"Suffridge","year":"2020","journal-title":"Front. Mar. Sci."},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1007\/s00248-012-0156-1","article-title":"The thiamine content of phytoplankton cells is affected by abiotic stress and growth rate","volume":"65","author":"Sylvander","year":"2013","journal-title":"Microb. Ecol."},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"121","DOI":"10.3354\/meps340121","article-title":"Seasonal phytoplankton nutrient limitation patterns as revealed by bioassays over Baltic Sea gradients of salinity and eutrophication","volume":"340","author":"Tamminen","year":"2007","journal-title":"Mar Ecol Progr Ser"},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"20756","DOI":"10.1073\/pnas.1009566107","article-title":"Most harmful algal bloom species are vitamin B1 and B12 auxotrophs","volume":"107","author":"Tang","year":"2010","journal-title":"PNAS"},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1146\/annurev.es.13.110182.002025","article-title":"Phytoplankton community ecology: the role of limiting nutrients","volume":"13","author":"Tilman","year":"1982","journal-title":"Ann Rev Ecol Syst"},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1023\/B:hydr.0000018206.02271.2b","article-title":"Growth and C:N:P ratios in copepods grazing on N- or Si-limited phytoplankton blooms","volume":"514","author":"Van Nieuwerburgh","year":"2004","journal-title":"Hydrobiologia"},{"key":"2023040123201945200_","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1039\/b703105j","article-title":"Elucidating biosynthetic pathways for vitamins and cofactors","volume":"24","author":"Webb","year":"2007","journal-title":"Nat. Prod. Rep."},{"key":"2023040123201945200_","doi-asserted-by":"crossref","DOI":"10.1007\/978-0-387-98141-3","volume-title":"ggplot2: Elegant Graphics for Data Analysis","author":"Wickham","year":"2009"}],"container-title":["Journal of Plankton Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/plankt\/article-pdf\/45\/2\/360\/49720435\/fbad004.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/plankt\/article-pdf\/45\/2\/360\/49720435\/fbad004.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,4]],"date-time":"2023-12-04T10:37:20Z","timestamp":1701686240000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/plankt\/article\/45\/2\/360\/7021941"}},"subtitle":[],"editor":[{"given":"Xabier","family":"Irigoien","sequence":"additional","affiliation":[]}],"short-title":[],"issued":{"date-parts":[[2023,2,1]]},"references-count":70,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2023,2,1]]},"published-print":{"date-parts":[[2023,4,1]]}},"URL":"https:\/\/doi.org\/10.1093\/plankt\/fbad004","relation":{},"ISSN":["0142-7873","1464-3774"],"issn-type":[{"type":"print","value":"0142-7873"},{"type":"electronic","value":"1464-3774"}],"subject":[],"published-other":{"date-parts":[[2023,3]]},"published":{"date-parts":[[2023,2,1]]}}}